Water Lecture Series
John Mekalanos discusses the biology of cholera, driven by his investigations on the molecular genetics of the causative bacterial organism. With his many colleagues in Bangladesh, Haiti, and elsewhere, he has provided strong evidence for how this organism emerged as a hu... Read More
Trypanosome Lytic Factor (TLF) has emerged as a novel arm of innate immunity that is only present in humans and select non-human primates. TLF was originally discovered in human blood as a minor form of High-density lipoprotein (HDL), also known as a good cholesterol, that rapidly kills the Afri... Read More
This simulation shows a dynamic molecular model of the bacterial cytoplasm, giving us a spectacular glimpse of the crowded conditions of the interior of a cell over a brief 15-microsecond time span. The model includes 50 of the most abundant types of macromolecules reported in Escherichia coli, ... Read More
Hydraulic fracturing, or “fracking”, is the process of drilling and injecting fluid into the ground at a high pressure in order to fracture shale rocks to release natural gas inside. What effect does this process have on the microorganisms that naturally exist in the water in this process?
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Patients getting medical care can catch serious infections called healthcare-associated infections (HAIs). While most types of HAIs are declining, one -- caused by the bacterium Clostridium difficile --continues to grow. C. difficile causes diarrhea linked to 14,000 American deaths each year. Pa... Read More
There is much interest in the role of nutrients and micronutrients in the support of host defense against infections. However, there is controversy in the ability of supplements to help prevent or treat infections. Speakers discuss research on the role of vitamin D supplements to prevent and/or ... Read More
A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Then it stretches the cell forward, following the light like a horse trotting after a carrot on a stick. This new ligh... Read More
This video looks at the microbial origins of the Black Death.
Plants associated bacteria play a key role in host productivity and health. These bacteria are phylogenetically diverse and form interactions considered neutral, beneficial or detrimental. A better understanding of these interactions will have a direct impact in agriculture by promoting sustaina... Read More
Vincent, Rich, and Kathy and their guests Clodagh and Ron recorded this episode at the 33rd annual meeting of the American Society for Virology at Colorado State University in Ft. Collins, Colorado.
Biology researchers from the University of Sydney, working with colleagues from Paul Sabatier Université in Toulouse have found that the brainless slime mold Physarum polycephalum, is able to use its slime trail as a memory device. In their paper published in the Proceedings of the National Acad... Read More
Should we only consider bacteria as harmful to our bodies?
Bonnie Bassler is a molecular biologist who has made a stunning discovery: bacteria 'talk' to each other using chemical signals that enable them to act as a unit, mount attacks and coordinate defence. This phenomenon of bacterial com... Read More
Almost 1 out of every 3 people in the United States will develop shingles during their lifetime. Despite the approval and recommendation by the FDA of a shingles vaccine for adults over 50, only 16% of American seniors over 60 are vaccinated. Vaccinations are even lower for those aged 50-60. A... Read More
An Ebola outbreak has killed at least 59 people in Guinea, UNICEF said, as the deadly hemorrhagic fever has quickly spread from southern communities in the West African nation.
Experts in the country had been unable to identify the disease, whose symptoms -- diarrhea, vomiting and fever -- we... Read More
Bacteria, unlike people, get more orderly when they're in large crowds. In this computer simulation, a few E. coli bacteria start out oriented perpendicular to the walls of a container (blue rods). As they multiply, the growing mass arranges into tidy columns parallel to the container walls (red... Read More
In the current issue of Science, researchers at Michigan State University demonstrate how a new virus evolves, which sheds light on how easy it can be for diseases to gain dangerous mutations.
The scientists showed for the first time how the virus called "Lambda" evolved to find a new way to ... Read More
A quick demonstration of how my Microbial Mania can impact the holiday season! Read More
Microscopic pathogens have been causing mass coral die-offs around the world. But now researchers are using high-speed video to spy on the behavior of killer microbes and potentially learn how to better manage coral disease.
“We finally have the tools to watch how bacteria behave in the ocean... Read More
The emergence of human infections with avian influenza viruses (H7N9 and H5N1) have raised concerns about the virus gaining the ability to spread person-to-person, potentially causing a deadly pandemic. So far the number of human cases has been limited but the mortality rates have been high. ... Read More