TWiM 4 Letters

Aric writes:

I just stumbled upon your podcasts last week and wanted to say that I enjoy them all (TWiV, TWiP, and TWiM). While listening to episode one of TWiM I began to think about the significance of finding human DNA in a bacterial genome. While this discovery is certainly very exciting I do have one question, doesn't the nature of LINEs make this discovery somewhat less remarkable? They are reverse transcriptases, which are built to copy and insert themselves into host DNA. I think this discovery may be due to the fact that LINE elements are very mobile sequences, and N. gonorrhoeae may be the 'victim' in this case. What are your thoughts on this? And would you feel different if the DNA found in the bacterial genome contained a gene for a membrane protein (or other random human gene) instead of a LINE?


Allie writes:

TWIV, TWIP, and now - of all things TWIM? it just doesn't get any better. As an adult 'back to schooler' and beginning-again science learner, I can't believe my luck at beginning my ed adventure into science and beyond, during the era of the "Axis of unsee-able"  - the TW's. Once I listen to a TW discussion, the book (especially those dratted ch's on microbe-human interactions and all the replication stuff - aarrggh) comes alive. Here I was last week wishing you TW guys had a microbiology podcast, and poof - my prayers are answered! I thought my ears would pop out of my head as I listened along to TWIM #1, and actually understood stuff! This makes learning fun! You guys have a somehow magical combination of hard-core geek-ism, humor, loopbacks to clarify things for the "LlL's" (less learned listeners), and way too cool: all the heavy hitters seem to be gettin' together to chit chat - thanks a 10(-)7th mol or something like that (clearly more to learn!) Let's vote you folks along with  Sal Khan as "egalitarian educators" of the year(s)..

(by the way the piece of human DNA stuck in there on Ng thing was really "eerie", as Sal Khan of Khan Academy would probably say. And, the copper thing - why can't microbes eventually get around that, like they get around everything else eventually  - temp, salinity, pH, penicillin? Years from now I'll realize this was a dumb question, but for now it has Viagra me wondering).



Kenneth writes:

Hi Vince, was just about to download TWiV when I saw that you have actually released the first episode to TWiM on the microbeworld website and I just can't stop jubilating. I strongly hope this podcast would be successful as TWiV and TWiP and I appreciate your help very much Vincent..You really helping some of us and I just cant thank you enough.

I pray for long life, happiness and good health for you, your family and all your friends helping you out to bring such an imparting tool in our lives and you all will be blessed anytime someone listens to any of your wonderful podcasts. This is just a thank you message and my questions will be following next.

All the best and goodluck.

Best Regards,

Ken (BioCrowd) in case you've forgotten me.

Stephen writes:

Here's a couple of ideas for signing off the show: "Another TWIM is added to the culture." "Another TWIM enters the culture." - Stephen

Atila writes:

Dear twimers,

First of all, congratulations to professor Racaniello and Racaniello Media Corporation for this new initiative. I am a regular TWiV and TWiP listener from Brazil, and just when I had listened to all episodes, you release this new podcast. Now I can only expect This Week in Vertebrates, or This Week in Plants. Until then, let me make my first TWiM question:

Many times I have heard the explanation that the smell that comes after the rain is caused by antibiotics produced by actinomycetes and other bacteria in a silent war for space. But I have never seen a decent reference to support this. People always say it but do not cite any source. Is it true, and do you have a good source for this?

Thank you all for making another fantastic podcast. I hope you inspire other researchers to do the same, or else Racaniello corp. will end up having 10 or more podcasts, and this is monopoly! Best, Atila Iamarino

p.s. thanks also for introducing Futures in Biotech, its a great podcast too and I am impressed. I'm listening to old episodes, from 2006 to 2008 and many of the discussions are about research that I have only heard last year. I'm anxious to get to the new episodes and know what will be published in 2015.


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