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Disarming a pathogen's ability to cause disease

The anaerobic, Gram-positive Clostridium difficile is a big problem. It causes rampant diarrhea and tissue necrosis, with more than 150,000 annual cases in the United States alone. Many of the disease manifestations of C. difficile are mediated by two exotoxins that C. difficile produces: TcdA a... Read More

Mosquito saliva enhances virus replication and disease

Mosquito saliva, which is injected into the host as a mosquito probes for a blood vessel, contains a collection of chemicals which include anticoagulants to prevent blood clotting, vasodilators to keep blood vessels wide, and anesthetics to prevent us from sensing the mosquito. Saliva also conta... Read More

Dispatches from ASM Microbe - Saturday

Welcome back to Dispatches from ASM Microbe! Today we’ll continue Microbe 2016 highlights of the microbiome, focusing on the non-human microbiome research being presented during the conference.

As mentioned yesterday, commencement of the National Microbiome Initiative was met with great exci... Read More

Classic Spotlights: Penicillin for the masses

The Journal of Bacteriology is celebrating its centennial this year – one hundred years of valuable scientific discoveries! To illustrate the wide variety of noteworthy results published over the years, the journal is publishing a Classic Spotlight series, in which experts in the field highlight... Read More

ASMCUE Happenings 2016

No matter the niche field a scientist pursues, there is one aspect of almost all career paths that scientists have in common: teaching. Whether lecturing a quorum of undergraduates about bacterial genetics, mentoring a research fellow as they learn the lab protocols, or presenting an invited lec... Read More

MMP #17: How bacteria can change graphene to propel rotors.

Host: Jeff Fox with special guests, Julia Yeomans and Vikas Berry.


Julia Yeomans of Oxford University in the United Kingdom and chemical engineer
Vikas Berry of the University of Illinois, Chicago, talk with Jeff Fox about their separate, but in some ways similar, research effor... Read More

TWiV 411: Chicken runs

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses.


Hosts: Vincent Racaniel... Read More

A Tiny Zika Laboratory

So far in this series I’ve written a good deal about our work on Zika virus, but I have said little about the people who are doing the science.

My lab at Columbia University Medical Center is very small, consisting of three people—Amy Rosenfeld, Audrey Warren, and me. Let me tell you about ... Read More

Tracking how bacteria threaten newborns

For years, researchers have struggled to get a handle on Group B streptococcus (GBS), in the hopes of improving neonatal outcomes. GBS are a bacteria commonly found in the vagina, rectum, and urinary tract of women. In healthy women, the bacteria are commensal, simply living without causing dise... Read More

In search of a better diagnostic assay for emerging fungal pathogen Candida auris

Misdiagnosis can lead to severe consequences for patients, and is a serious clinical issue. The newly emerging Candida auris requires higher doses of antifungal medications to treat an infection than does C. albicans, highlighting the importance of proper diagnosis. Thus far, the most accurate d... Read More

Microbial Awards Season in Biology 350!

I like to encourage my students to explore the intersection between art and microbiology. Science + art = awesome! In any event, in this blog post, I describe two microbial art competitions in my microbiology course at the University of Puget Sound. I think my micronauts did some remarkable w... Read More

BacterioFiles 274 - Proteobacteria Purify Piscine Pee

This episode: Bacteria in the gills of fish help break down their metabolic wastes before they reach toxic levels!


(7.4 MB, 8.1 minutes)


Show notes: 


Read More

BacterioFiles 271 - Dictyostelium Delivers DNA Deathtraps

This episode: Slime molds have special cells that capture and kill bacteria using traps made of DNA!


(11.2 MB, 12.25 minutes)


Show notes: 



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Commonly Cited Stat of 10 Bacteria for Every 1 Human Cell Is Wrong

In a new paper, researchers debunk the common myth that in the human microbiome, bacteria outnumber human cells 10-to-1. By examining the colon, the researchers estimate that the total number of bacteria in the human microbiome is 38 trillion (for the average 70-kg man). For comparison, the auth... Read More

TWiV 410: Hurricane Zika

Sharon and Scott join the TWiV team to talk about their work on dengue antibody-dependent enhancement of Zika virus infection, and identifying the virus in mosquitoes from Miami.


Hosts: Vince... Read More

"The Amazing Adventures of the Virologists” Part One - Vaccines _ 6

"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
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ACKNOWLEDGMEN... Read More

Technological advances reveal finer details about chronic infection

How do chronic infections change over time? This is the broad question addressed in recent research published in the Journal of Virology. In their study, a team of scientists headed by Fabio Luciani investigated a hepatitis B virus infection over a course of 15 years.

Hepatitis B virus (HBV) ... Read More

New vaccines againts zika can prevent neurological disorders in newborn mice

Two vaccines against Zika virus developed at the University of Pittsburgh School of Medicine have successfully conveyed immunity from female mice to pups conceived weeks after the mother's vaccination.

When challenged with Zika virus within a week of their birth, both vaccines protected the p... Read More

Happy Luxmas 2015!

In this blogpost, I celebrate the microbiological season with some microbial merriment: ice nucleation bacteria, drawing with reporter gene bacteria, and painting with bioluminescent microbes. Every day is Luxmas to me! Read More

Chlorhexidine use may select for colistin resistance

Infection control is a vital part of maintaining a safe healthcare facility, and the use of biocides and disinfectants to eliminate potential pathogens is an important part of infection control strategy. Pathogens can spread among patients via transfer to surfaces like doors, floors, and counter... Read More
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