The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells.
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Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.
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Welcome back to Dispatches from ASM Microbe! Today we’ll continue Microbe 2016 highlights of the microbiome, focusing on the non-human microbiome research being presented during the conference.
As mentioned yesterday, commencement of the National Microbiome Initiative was met with great exci... Read More
mSphereDirect is an exciting new pathway to publish your research! This groundbreaking new submission path puts you in control of getting your original research reviewed and published as soon as possible. We’ve prepared the most important things to keep in mind while preparing your manuscript s... Read More
No matter the niche field a scientist pursues, there is one aspect of almost all career paths that scientists have in common: teaching. Whether lecturing a quorum of undergraduates about bacterial genetics, mentoring a research fellow as they learn the lab protocols, or presenting an invited lec... Read More
Many mBiosphere readers will know that the influenza A virus infects multiple species, and this ability to infect birds, humans, and other mammals such as pigs is one of the ways virions can exchange genetic information, leading to new viruses able to cause major outbreaks. However, few mBiosphe... Read More
So far in this series I’ve written a good deal about our work on Zika virus, but I have said little about the people who are doing the science.
My lab at Columbia University Medical Center is very small, consisting of three people—Amy Rosenfeld, Audrey Warren, and me. Let me tell you about ... Read More
I like to encourage my students to explore the intersection between art and microbiology. Science + art = awesome! In any event, in this blog post, I describe two microbial art competitions in my microbiology course at the University of Puget Sound. I think my micronauts did some remarkable w... Read More
For years, researchers have struggled to get a handle on Group B streptococcus (GBS), in the hopes of improving neonatal outcomes. GBS are a bacteria commonly found in the vagina, rectum, and urinary tract of women. In healthy women, the bacteria are commensal, simply living without causing dise... Read More
Food microbiology is an important issue we cover on this blog, because food safety is vital to prevent foodborne illness. The use of technologies like whole-genome sequencing help identify and pinpoint the source of microbial contaminants, but how do microbes become contaminants in the first pla... Read More
In a new paper, researchers debunk the common myth that in the human microbiome, bacteria outnumber human cells 10-to-1. By examining the colon, the researchers estimate that the total number of bacteria in the human microbiome is 38 trillion (for the average 70-kg man). For comparison, the auth... Read More
This episode: Algae growing in Arctic snow make red pigments that heat up their surroundings!
(6.8 MB, 7.5 minutes)
Ne... Read More
It was a peer review request that got Alessia Ruggieri and her group at University of Heidelberg to look more closely at how Dengue virus manipulates the cellular translation and stress machineries during infection.
In a previous study, Ruggieri showed that Hepatitis C virus infection induced... Read More
The hamlet of Resolute Bay is a tiny Arctic village in the Nunavut territory of Canada with a population that hovers at or below 300. Over hundreds of perhaps even thousands of years, the traditional Inuit diet in Resolute Bay and elsewhere has been dictated by the Arctic environment. The diet i... Read More
"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
ACKNOWLEDGMEN... Read More
The TWiV academia discuss induction of diarrhea by the capsid protein of an astrovirus, and association of a fungal RNA virus with white-nose syndrome of North American bats.
It has been assumed that mothers pass on gut microbes to their infants during and just after delivery, a process called vertical transmission, but because of technical restraints, the evidence of this occurring has been limited. Previous cultivation-free studies have observed the same microbial ... Read More
How do chronic infections change over time? This is the broad question addressed in recent research published in the Journal of Virology. In their study, a team of scientists headed by Fabio Luciani investigated a hepatitis B virus infection over a course of 15 years.
Hepatitis B virus (HBV) ... Read More
I hope we have all had an opportunity over the past holiday weekend to give thanks for what we have—it is important to step back and reflect from time to time on the many benefits and advantages we have. It can help us realize what we have achieved, and the multitude of people and resources that... Read More
Microbial infection is implicated in an ever-growing number of types of cancer. Adding to the already long list of microbial-associated cancers, an increasing body of evidence suggests breast cancer may also be associated with a specific microbial milieu. A report in Applied and Environmental Mi... Read More