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And now for something completely different: optimistic news from the world of antibiotic stewardship

There’s no way to avoid the news of a growing concern for drug-resistant infections. In both life-threatening and relatively superficial infections, the ability to successfully treat microbial infections with antimicrobials is decreasing. Our only recourse is to use the drugs we have carefully w... Read More

TWiV 421: Like flies on shot

The TWiVnauts present another example of an infectious but replication incompetent vaccine, an insect specific arborvirus bearing chikungunya virus structural proteins.


Hosts: Vincent Racaniello,&n... Read More

A chromosome in every cell: PprA funcitons in chromosome segregation after Deinococcus radiodurans irradiation

Exposure to reactive oxygen species, exposure to ionizing radiation, exposure to UV light – all of these are dangerous because of their potential to alter DNA sequences. Changes in DNA can affect a protein coding sequence, potentially influencing its function, but changes in regulatory regions c... Read More

False impressions in predatory publishing

Imitation may be the sincerest form of flattery, but it can also be the easiest way to make a buck. That’s the primary motivation for camouflaging within an already-established brand: Sunbucks, McDowell’s, and Mountain Lightening all rely on brand recognition – of a brand that isn’t their own. W... Read More

Researchers Identify Multidrug-resistant E. coli Bacteria from a New Jersey Patient

Antimicrobial resistance has been a growing concern in the health care community. But a publication by Chinese researchers in The Lancet Infectious Diseases last fall kicked things up a notch. The work found the mcr-1 gene, which confers resistance to the antibiotic colistin, in Escherichia coli... Read More

Zika Virus in the USA

On this episode of Virus Watch we cover three Zika virus stories: the first human trial of a Zika virus vaccine, the first local transmission of infection in the United States, and whether the virus is a threat to participants in the 2016 Summer Olympic and Paralympic Games. Read More

Unlocking cryptic Strepomyces genes in the search for potential new antibiotics

Actinobacteria are the bacterial phylum responsible for production of many clinically-relevant antibacterial compounds. Streptomyces is a soil-dwelling genus of actinobacteria that produces drugs like neomycin and chloramphenicol. Despite deriving many antibiotics already from Streptomyces, coul... Read More

Onward toward a Zika vaccine

On Monday, August 1, the US Centers for Disease Control and Prevention recommended that pregnant women not travel to Wynwood, a neighborhood north of downtown Miami, because health officials in Florida had found that mosquitoes there are actively transmitting Zika, a mosquito-borne virus that ca... Read More

Cross-respiration breathes life into a periodontal pathogen

Microbiome research has revealed that there are good guy and bad guy bacteria living together in complex communities on our skin, in our mouths, throughout our guts and pretty much everywhere in between. But what do you call a good guy bacterium that is aiding and abetting a disease culprit?

... Read More

ASM Members Deliver a Landslide Endorsement for Governance Change - Part I

Change does not come easily to most organizations, let alone to one with more than a century of history. Indeed, twice before ASM tried—and failed—to change its governance structure. This time, ASM members embraced change, realizing that ASM must become more modern and more nimble in its decisio... Read More

Is it safe to go into the ocean? Standardizing molecular methods for water safety surveillance

Have you ever gone to the beach, ready for a day of sun and sand, only to find a warning sign? One of the most common reasons beaches close is due to the presence of coliform bacteria. These indicator bacteria, such as Escherichia coli, are used as markers for fecal waste, since their presence c... Read More

#microMOOCSEM: the first microbiology massive online open course by Twitter (in Spanish)

Veintinueve profesores e investigadores de 20 universidades y centros de investigación van a colaborar para impartir el primer curso mundial online gratuito vía Twitter sobre microbiología. La iniciativa está coordinada y organizada por el grupo de Docencia y Difusión de la Microbiología de la S... Read More

Structure and genome of Zika virus

Group: Group IV ((+) ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Species: Zika virus

Structure of Zika Virus
•The virion is approximately 40 nm in diameter with surface projections that measure roughly 5-10 nm.
•Nucleocapsid is 25-30 nm in diameter surrounded by a host-membrane derive... Read More

TWiM #141: Nutritional immunity and polymicrobial infections

Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.


Hosts: Vincent Racaniello, ... Read More

Microbes in Raw Milk Influenced by Dairy Cow Environment

Raw milk collected from dairy farms has to travel to processing facilities before it is transformed into the delicious dairy products we consume. Because the milk from many dairy cows is collected together, any contamination issue from a single animal can lead to spoilage or contamination. How r... Read More

The Zika Effect

Having worked on viruses for over 40 years, I know a fair number of people in the field, and I am amazed at how many of them have started to work on Zika virus. What exactly is attracting virologists to this emerging virus?

There are probably many reasons why Zika virus would be of interest t... Read More

An Earth Day Shout-out to Microbes

So another Earth Day has come and gone. How did you spend yours? If you spent the entire day asleep, you used about half a kilogram of oxygen. Since I assume that you are alive and kicking, you probably consumed more oxygen than that. If you went about your normal business during the day, you pr... Read More

New tools to detect new virus

In fall 2015, a new human hepegivirus (HHpgV-1) was identified by using a novel, high throughput sequencing technique. Concerns were raised that this virus was found in blood to be used for transfusions, potentially passing on the infection. But without tools to test for its presence, there was ... Read More

TWiV 419: The selfless gene

The TWiVrific gang reveal how integration of a virophage into the nuclear genome of a marine protozoan enhances host survival after infection with a giant virus.


Hosts: Vincent Racaniello Read More

The inflammatory nature of a bad recycler

Being a bad recycler implies creating more waste because items aren’t being reincorporated into the production chain. Plastic water bottles can be broken down and turned into new plastic bottles, gardening gloves, or fleece – any of which means less oil needs to be harvested and refined to the p... Read More
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