Viruses that are harmless to humans might help fight the deadly scourge of bacteria that can't be treated with antibiotics, researchers say.
These viruses could be used in hand santizers, and to treat exposed surfaces in hospitals, which are hotbeds of antibiotic resistance, the researchers n... Read More
First of the three videos related to research article appearing in Lab on a Chip. I. H. Riedel-Kruse et al "Design, Engineering and Utility of Biotic Games". Read the article by clicking "source" above.
From the abstract:
Games are a significant and defining part of human culture, and thei... Read More
Jason Roberts, a virologist at the Victorian Infectious Disease Reference Laboratory in Melbourne, Australia, creates three-dimensional simulations of viruses showing how the molecules that make up the capsid and genome might move in very short periods of time. I visited Jason in his laboratory ... Read More
A new study led by researchers at the University of Minnesota has found a three-way link among antibiotic use in infants, changes in the gut bacteria, and disease later in life. The imbalances in gut microbes, called dysbiosis, have been tied to infectious diseases, allergies and other autoimmun... Read More
The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague — according to a citywide microbiome map published today by Weill Corne... Read More
Last Fall, the great Dr. Margaret McFall-Ngai "virtually visited" my freshman writing class at the University of Puget Sound to discuss symbiosis and Microbial Supremacy with my new students. I had my students read some papers by Dr. McFall-Ngai (including the wonderful "Animals in a Microbial ... Read More
Referenced dataset of host/pathogen interactions for Borrelia burgdorferi: linked to Kegg pathway interactome analysis Read More
Here is my annual blogpost using #MicrobialSupremacy to wish all readers a very, very happy holiday season. I do this GFP and prodiosin, as well as luciferase! Enjoy a tiny bit of microbial art, relevant to the season? Read More
Throat swab of (5) years old child from emergency department for culture and sensitivity clinical summary scarlet fever.
Streptococcus pyogenes, or Group A Streptococcus, is a spherical, Gram-positive bacterium. S. pyogenes displays streptococcal group A antigen on its cell wall and typic... Read More
Chronic wasting disease is a prion disease of cervids (deer, elk, moose) that is potentially a threat to human health. A role for environmental prion contamination in transmission is supported by the finding that plants can take up prions from the soil and transmit them to animals. Read More
A common denizen of the undergraduate microbiology laboratory, Serratia marcescens is well known for the production of a bright red pigment, prodigiosin. Prodigiosin has been investigated over many years for its possible antimicrobial, antifungal, and even antitumor effects. Still, the relevan... Read More
Virus populations do not consist of a single member with a defined nucleic acid sequence, but are dynamic distributions of nonidentical but related members called a quasispecies (illustrated at left). While next-generation sequencing methods have the capability of describing a quasispecies, the ... Read More
A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved.
Adenovirus CG0070, designed to treat bladder cancer, and adenovirus O... Read More
Rhinovirus is the most frequent cause of the common cold, and the virus itself is quite common: there are over 160 types, classified into 3 species. The cell receptor has just been identified for the rhinovirus C species, which can cause more severe illness than members of the A or B species: it... Read More
This one is a bit more tricky; both Giardia and Cryptosporidium are possible. The symptoms are more those of Cryptosporidium, so that would be my semi-educated guess. Most of that education comes through you, with some help of some CDC... Read More
In this blog post, I discuss making student designed artwork using bioluminescent bacteria as "paint." As student "buy in" is critical for any course, such fun "creative" approaches act synergistically to improve learning and outcomes. Feel free to vote on your top six images---the students ar... Read More
Viruses can be broadly classified according to whether or not the particle is enveloped – surrounded by a membrane taken from the host cell – or naked. Some naked viruses apparently are more modest than we believed. Read More
This study investigates how the overexpression of a specific ORF affects the virulence of E. faecalis. Read More
A new study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease. The report also finds what appear to be consistent differenc... Read More