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TWiEVO 3: Recombination is for the birds

In episode #3 of the new science show This Week in Evolution, Nels and Vincent examine another important driver of evolution: recombination. The results of two papers in which the process is studied in finches and in yeast lead to the unexpected conclusion that recombination evolves more slowly ... Read More

TWiV 381: Add viruses and Zimmer

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiEVO 5: Looking at straw colored fruit bats through a straw

We have some virology for you on the latest episode of the science show This Week in Evolution. Nels and I are joined by Kartik Chandran and Sara Sawyer who talk about their work showing how the filovirus receptor NPC1 controls susceptibility of bats to Ebolavirus infection. They have found that... Read More

TWiEVO 2: Faster than a speeding virus

On episode #2 of the new science show This Week in Evolution, Nels and Vincent talk about how a cellular enzyme contributes to the very high mutation rate of human immunodeficiency virus type 1.

You can find TWiEVO #2 at microbe.tv/twievo. Read More

Francis Crick Portrait in Living Light!

This is as portrait of the late Francis Crick created by my wife Dr. Jennifer Quinn using "paint" of luminous bacteria. Photobacterium leignothi was grown in LB amended to 20g/l NaCl for a few hours until visible luminescence was detected visually. The liquid culture was painted onto amended L... Read More

Shiga toxin: no preassembly required

The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More

Assessing gram stain error rates

Because of its simplicity and the rapid time-to-result turnaround, gram staining plays an important role in clinical microbiology. Learning the cell structure helps eliminate potential disease etiologies: learning an isolate is a gram-negative rod doesn’t tell you what the diagnosis is, but it h... Read More

Researchers hope hybrid compounds can sensitize and inhibit malaria parasites in one blow

Because of its safety, efficacy, and affordability, chloroquine remains the treatment of choice for all Plasmodium species, except in regions with chloroquine-resistant P. falciparum. Chloroquine-resistant protists are treated with combination therapy, which includes artemisinin-derived molecule... Read More

Cities have individual microbial signatures

Greg Caporaso was sifting through blog posts on microbe.net, which covers the microbiology of built environments, when a study idea sparked for him and colleagues Jeff Siegel, Scott Kelley and Rob Knight.

“It became clear to me that there was a lot of interesting work being done to understand... Read More

New promise for treatment of enterovirus infection

Feeling a bit under the weather? There’s a decent chance you’re suffering from an infection with an enterovirus. Enteroviruses are a commonly encountered virus, especially in the summer and fall. They can cause a variety of symptoms, from cold-like symptoms such as runny nose or fever to more se... Read More

Toward development of microarrays to test water safety

Imagine taking an ocean-side vacation, with the sun, sand, and water lulling you to relaxed bliss. After day at the beach, you experience an intense bout of stomach cramps and – more delicately put – GI distress. A rare day off is ruined because of a bug you picked up. Next, imagine a situation ... Read More

Discovery of the Sixth DNA base?

Scientist has described the possible existence of sixth DNA base, the methyl-adenine (mA) this week.

Deoxyribonucleic acid (DNA) is a polymer of nucleotides, which encodes every genetic information of living existence. The entire genetic information are stored within DNA as the form of millio... Read More

TWiV 386: The dolphins did it

Hosts: Vincent RacanielloRich Condit, and  Read More

Communicating your science via social media

ASM aims to promote and advance the microbial sciences in a myriad of ways. In addition to promoting scientific education and discoveries, we also hope to engage the public with the diverse world of microbes! Last year, we held our first Agar Art contest, to highlight the often-overlooked beauty... Read More

Systems study of climate change effects, large and small

If there is a problem built for a systems-based research approach, climate change – with its complex carbon and nitrogen cycles, numerous species involvement, and interaction of geographical zones – would be an excellent candidate. Concurrent with the launch of the systems-based microbial resear... Read More

Diagnostic guidelines for bloodstream infections aim to shorten time to accurate therapy

One of the most dangerous places for an infection to occur is in the bloodstream. Septicemia, when microbes are present in the blood, not only allows bacteria access to other internal organs through the highway of our circulatory system, but also can cause a massive inflammatory response, leadin... Read More

Rubella virus and birth defects

Amidst the fear surrounding Zika virus, remember that there are over 100,000 children born each year with birth defects caused by infection with rubella virus.

Rubella virus is a member of the Togaviridae family, which also includes chikungunya virus. The genome is a 9.7 kilobase, positive st... Read More

Colors of Superbug !

Methicillin Resistant Staphylococcus aureus (MRSA) isolated from animals. The organism was grown on seven different agar medium. On blood agar (Centre), it forms small to medium sized colonies surrounded by weak beta-hemolysis. It shows diverse types of color in different chromogenic medium- pin... Read More

Fighting viruses - amazing new 21st century lab

Looking out of the window isn’t something most office workers would consider a luxury. But then, most people don’t work in a maximum security, biosafety level 4 high-containment research facility, working to protect the UK’s multi-billion pound agricultural industry from dangerous and highly inf... Read More

Meta-analysis of urine pre-analytic practice reveals need for rigorous studies

Evidence-based medicine is the approach used by doctors to make rational clinical decisions based on rigorous, well-controlled studies. By minimizing hunches, gut feelings, and anecdotal evidence, physicians and patients can follow recommendations that are most likely to have a positive outcome.... Read More
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