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TWiM #136: Diderms and then monoderms

The TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.


Hosts: Vincent Racaniello, El... Read More

Antibiotic stewardship - a community effort

As we highlighted in our previous blog, antibiotic stewardship – the careful use of appropriate antibiotic administration – can have positive effects. A small change from a difference in clinical lab reporting led to less drug use, which led to fewer drug-resistant infections. When we think of a... Read More

Microbes Found on New York City ATM Keypads Mostly from Human Skin, Food

Mapping and identifying all the microbes across New York City is no small feat. Just ask Jane Carlton. About three years ago, Carlton, director of the Center for Genomics and Systems Biology, and professor of biology, at New York University and colleagues won an NYU grand challenge grant for the... Read More

New promise for treatment of enterovirus infection

Feeling a bit under the weather? There’s a decent chance you’re suffering from an infection with an enterovirus. Enteroviruses are a commonly encountered virus, especially in the summer and fall. They can cause a variety of symptoms, from cold-like symptoms such as runny nose or fever to more se... Read More

BacterioFiles 275 - Building Bacterial Batteries

This episode: Scientists build a battery out of microbes and electrodes that can store and release electricity repeatedly!


(7.5 MB, 8.1 minutes)


Show notes: 


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TWiV 404: Not found

From the twiVivants, follow up on FluMist and Zoster vaccines, Zika virus update, and isolation of a multicomponent animal virus from mosquitoes.


Hosts: Vincent Racaniello Read More

Microbial Identification and Tracking: the Next Generation

How do you identify an unknown microbe? If you’ve taken an introductory microbiology lab course in the past twenty years, chances are you were assigned an unknown bacterium that you had to identify through differential media and biochemical assays. Newer techniques like qPCR are being standardiz... Read More

Tracking Bacterial Imbalance in the ICU

The human microbiome is the diverse population of microorganisms that live on and in the body. Many thrive on the skin and in the mouth, but the majority live in the intestines. Over the last decade or so, microbiologists have become increasingly aware of how a person's microbial mix likely play... Read More

Ancient clay remedy proves its antibacterial powers in the lab

Near Kisameet Bay on the central coast of British Columbia sits a deposit of clay that covers 5 acres and spans a depth up to 42 feet in places. This vast smear formed 10,000 years ago as glacial melt filled a granite basin and fine minerals silted out.

The ancient clay likely holds secrets t... Read More

TWiM #139: Frackibacter and sticky fingers

The TWiM team discusses microbial DNA found on ATM machines in New York City, and how hydraulic fracturing, or fracking, alters microbial ecosystems deep in the Earth.


Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson.


{audio}This Week in Mi... Read More

Microbiology Myths Debunked: Scientific Analysis of the Five Second Rule

While walking through your house, you drop a granola bar you were eating. Quick – do you pick it up and eat it? Is the ground too dirty to eat from? Does the amount of time the food sits on the ground matter? Will more microbes gather onto the snack as you decide whether or not to continue noshi... Read More

The classic and current studies of bacterial endospore morphology

Recently, one of the Journal of Bacteriology Classic Spotlight series highlighted the numerous studies on bacterial spores that have been published in the journal throughout the years. Bacterial endospores, the resilient and relatively quiescent bacterial structures first identified in the 1800s... Read More

BacterioFiles 276 - Single-cell Slime School

This episode: Individual slime molds show the ability to learn about their environment!


(8.8 MB, 9.6 minutes)


Show notes: 


News item... Read More

TWiV 415: Ebola pipettors and the philosopher's clone

Jeremy, Aaron, and Ted join the TWiV team to discuss their work on identifying a single amino acid change in the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells.


Hosts:  Read More

TWiV 414: Zika in the guys with Diamond

Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication.


Hosts:  Read More

Targeting the gut microbiome to fight heart disease

Is the way to treat heart disease through a person's stomach? According to a new study, the answer is yes. Researchers have found that a compound found in red wine, resveratrol, reduces the risk of heart disease by changing the gut microbiome.

Cardiovascular disease remains the leading cause ... Read More

BacterioFiles 267 - Crust Color Cooks Communities

This episode: Cyanobacteria in biocrusts produce pigments that heat their surroundings up to 10 degrees hotter!


(7 MB, 7.6 minutes)


Show notes: 
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Environmental disturbances decrease the variability of microbial populations

A central pursuit of microbial ecology is to accurately model changes in microbial community composition in response to environmental factors. This goal requires a thorough understanding of the drivers of variability in microbial populations. However, most microbial ecology studies focus on the ... Read More

Enhanced virus transduction may lead to more effective gene therapy

A benefit of the voluminous wealth of research produced is that it allows us to stand on the shoulders of giants – we can take advantage of established facts, tools, and datasets. This may mean using a mutant library to find genes in your organism that are important for the process you study; ac... Read More

And they're off! An overview of ASM resources on Olympic-related infectious disease reports

The opening ceremony for the Summer Olympics 2016 will be held this Friday, marking the onset of two weeks of competition between the world’s best athletes. The world has been focused on Brazil and its preparedness – not only for the infrastructure required for the games, but also for any potent... Read More
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