The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV)... Read More
This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!
(10 MB, 10.8 minutes)
This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!
(7.7 MB, 8.4 minutes)
Read about Angelina Fanny Hesse, an unsung heroine of microbiology who helped make the isolation of bacteria possible in this Popular Science blog post by Christina Agapakis:
"In the earliest days of microbiology, scientists were stumped about how to isolate bacteria. That is, until the fami... Read More
Many people have a new awareness of the disease known as amyotrophic lateral sclerosis, or ALS, thanks to the Ice Bucket Challenge initiated by the ALS Association. Fewer might know that retroviruses have been proposed to play a role in the development of the disease. Read More
Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.
Host: Read More
Antigenic variation is a hallmark of influenza virus that allows the virus to evade host defenses. Consequently influenza vaccines need to be reformulated frequently to keep up with changing viruses. In contrast, antigenic variation is not a hallmark of poliovirus – the same poliovirus vaccines ... Read More
Six new cases of Heartland virus disease have been identified in residents of Missouri and Tennessee. The cause of this disease appears to be a member of the Phlebovirus genus in the Bunyaviridae family that was first identified in 2009 and appears to be transmitted by the Lone Star tick (Amblyo... Read More
The 1918 influenza pandemic was particularly lethal, not only for the very young and the very old (as observed for typical influenza), but unexpectedly also for young adults, 20 to 40 years of age (pictured). It has been suggested that the increased lethality in young adults occurred because the... Read More
In the spring of each year I teach a virology course to undergraduates and masters students at Columbia University. I produce video recordings of all my lectures not only for students in the course, but for anyone else who is interested in learning about viruses.
You can find my virology lect... Read More
This episode: Engineered phages can both kill bacteria and disrupt their communications!
(14.8 MB, 16.2 minutes)
Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More
Until we have "action figures" of scientists, I do what I can to recognize scientists that have had a large and lasting influence on my academic career. In this blog post, I praise Dr. Moselio Schaechter for his clear and insightful approaches to microbiology. His enthusiasm, breadth of interes... Read More
Given the extent of the Ebola virus outbreak in West Africa, transport of an infected individual to the US was bound to happen. The case is an adult who had contact with an Ebola virus-infected woman in Liberia, then traveled to Dallas. He had no symptoms before arriving in the US and therefore ... Read More
The coronavirus responsible for Middle East Respiratory Syndrome (MERS) is prevalent in camels throughout Saudi Arabia and has been around for at least 20 years, according to a study to be published in mBio®, the online open-access journal of the American Society for Microbiology.
“Our study ... Read More
This week’s virology question comes from Eric, who writes:
I’m working on an MPH and in one of my classes we are currently studying the influenza virus. I’d forgotten that the genome is in 8 separate parts. Curious, I’ve been searching but can’t find any information as to why that is?
What... Read More
DNA microarrays are widely used in biological research and were once thought to be a very promising gene discovery tool. However, since the advent of next generation DNA sequencing, the popularity of DNA microarrays has steadily declined. Compared to the sequencing, microarray behavior is unce... Read More
The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.
During the winter of 1962 in California, a new virus was isolated from the oropharynx of 4 children who had been hospitalized with respiratory disease that included pneumonia and bronchiolitis. On the basis of its physical, chemical, and biological properties, the virus was classified as an ente... Read More
A recent study by scientists at the Ludwig Center for Cancer Immunotherapy offers a new, multifaceted therapy for destroying tumors. A team of researchers led by Dmitriy Zamarin combined checkpoint blockade, a technique aimed at enhancing antitumor immune responses, with oncolytic viral therapy,... Read More