Spongiform encephalopathies are neurodegenerative diseases caused by misfolding of normal cellular prion proteins. A 2014 case of variant Creutzfeldt-Jacob prion disease in the United States was probably caused by eating beef from animals with bovine spongiform encephalopathy (BSE), or mad cow d... Read More
This episode: Marine worms and their microbial symbionts can live on the toxic gas carbon monoxide!
Reminder: this is the last episode for at least a few weeks while I am wrapping up my PhD. See you again when I'm done!
(11.1 MB, 12.1 minutes)
This episode: When digesting wood, shipworms outsource their microbial symbionts from gut to gills!
(9.7 MB, 10.6 minutes)
Host: Vincent Racaniello
Guest: Ileana Cristea
Vincent meets up with Ileana at Princeton University to talk abou... Read More
This episode: Of genes that are similar in yeast and humans, almost half of the yeast versions are functional when replaced with the human version!
(7.9 MB, 8.5 minutes)
This episode: Bacterial ghosts could make good vaccines for different things!
(9.8 MB, 10.7 minutes)
A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More
I am a big fan of TWIP. You do so many things right, that a little problem in your TWiP94 broadcast is not a big deal. As you may already know all three drugs in the Nutman et al. study are small molecules, not monoclonals, the... Read More
This slideshow outlines the work of WHOI scientists Tracy Mincer and Kristen Whalen in the quest to beat antibiotic resistance through bioprospecting in the ocean. Read More
Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More
Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Read More
The TWiP trifecta solves the case of the Professor Who Went to Brazil, and discuss an amazing case of a tapeworm that turned into a tumor in an AIDS patient.
Hosts: Read More
Watch the pilot episode of BioFilms in which we explore some creepy microbes just in time for Halloween. Learn how algae can suffocate a pond of all its life, discover the vampire bacterium known as Vampirococcus who literally sucks the life out its victims, and watch out for those sweet Hall... Read More
Here's my summary of ASM2015, an exciting weekend full of science.
(11.5 MB, 12.5 minutes)
This episode: Cable bacteria and algae set up electric grid in sediments!
(6 MB, 6.5 minutes)