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Getting Started with MicrobeWorld

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BacterioFiles 248 - Tiny Travelers Transport Toxin Trashers

This episode: Bacteria that swarm around in groups carry other bacteria with them that can be helpful for degrading toxins!


(14.2 MB, 15.5 minutes)


Show notes: 
Read More

TWiV 385: Failure

Hosts: Vincent Racaniello and Dickson Despommier


Guest: Stuart Firestein Read More

Identifying milk components that promote a healthy infant microbiome

Breast milk provides an inexpensive, nutrient-filled source of food for babies. Because of this, the American Academy of Pediatrics and the WHO recommend new mothers to exclusively breast feed their babies for the first six months of life, and continue up to two years (supplemented with other fo... Read More

Zika virus, like all other viruses, is mutating

Not long after the appearance of an outbreak of viral disease, first scientists, and then newswriters, blame it all on mutation of the virus. It happened during the Ebolavirus outbreak in West Africa, and now it’s happening with Zika virus.

The latest example is by parasitologist Peter Hotez,... Read More

MdlM117: Chagas, una infección olvidada...., por los países industrializados con Michael Levy

Hoy tenemos la suerte de contar con la compañía de Michael Z. Levy, Catedrático Asistente de Epidemiología en el Departamento de Bioestadística y Epidemiología de la Universidad de Pennsylvania, EE.UU.


Michael ha sido un incansable trabajador en el area de control/eliminación del vect... Read More

Phage diffusion on a bacterial lawn: not all plaques are created equal

Like us, bacteria have their own microbial attackers, in the form of bacteria-specific viruses called bacteriophage, or phage. These phage come in a variety of flavors but can be broadly categorized into virulent, which immediately begin to replicate and lyse (burst) the infected cell quickly, a... Read More

TWiP 107: Parasites leave a bad taste in my gut

The TWiPtastic trio solves the case of the Surfer from Switzerland, and reveal how taste-chemosensory tuft cells in the gut regulate immune responses to parasites.


Hosts: Vincent Racaniello,&n... Read More

BacterioFiles 247 - Animalcule Acetate Ameliorates Asthma

This episode: Feeding mice high-fiber diets reduces their risk of allergic airway disease, even across generations!


(12.1 MB, 13.2 minutes)


Show notes: 
Read More

TWiV 384: Agent 003, a view to a fish kill

Hosts: Vincent RacanielloDickson DespommierAlan Dove and  Read More

MMP #11: Reexamining the emergence of land plants based on an analysis of the cell walls of charophycean green algae.

Host: Jeff Fox with special guests, Øjvind Moestrup, Peter Ulvskov, and Jesper Harholt.


Øjvind Moestrup and Peter Ulvskov, both at the University of Copenhagen and Jesper Harholt at Carlsberg Laboratory, also in Copenhagen, Denmark, talk with Jeff Fox about their hypothesis about terr... Read More

Structure and genome of Zika virus

Group: Group IV ((+) ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Species: Zika virus

Structure of Zika Virus
•The virion is approximately 40 nm in diameter with surface projections that measure roughly 5-10 nm.
•Nucleocapsid is 25-30 nm in diameter surrounded by a host-membrane derive... Read More

A virus-like particle vaccine against RSV is safe and effective in mice

Pneumonia remains a serious worldwide problem, especially among the young, elderly, and immunocompromised. Over 900,000 children die each year due to the disease, and respiratory syncytial virus (RSV) is the most common viral cause (Streptococcus pneumoniae and Haemophilus influenzae type b bein... Read More

TWiM #125: A minimal cell operating system

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.


Hosts: Vincent Racaniello, Read More

TWiM 125 Letters

Inspired by William:


Dear TWiMers;
Greetings from Berkeley where miracle March (water-wise) was perhaps half a miracle, but that is definitely better than none. At least we will not run out of water this summer.


I found this quasi-synthetic biology result... Read More

Targeting the gut microbiome to fight heart disease

Is the way to treat heart disease through a person's stomach? According to a new study, the answer is yes. Researchers have found that a compound found in red wine, resveratrol, reduces the risk of heart disease by changing the gut microbiome.

Cardiovascular disease remains the leading cause ... Read More

International Team Fishes New Virus Out of the Sea of Galilee

In 2009, fish in Israel began dying in droves. And not just any fish, but the St. Peter’s fish, tilapia in the Sea of Galilee—the fish famed in the Bible for feeding the multitudes and paying the temple tax for St. Peter.

As head of the fish disease laboratory for Israel’s Ministry of Agricul... Read More

Does the hologenome address the whole picture?

How do we define the genetic makeup of an individual? Is it the genetic material found in each cell of that individual (that’s not entirely accurate; mutations and recombinatorial differences can lead to multiple genomes in one individual). And what about the genes carried by our microbiome? The... Read More

BacterioFiles 246 - Prowling Protist Predator Packs

This episode: Amoebas in soil gang up on and eat much larger roundworms!


(10.5 MB, 11.3 minutes)


Show notes: 
Journal Paper
... Read More

A minimal cell operating system

If the DNA sequence of a cell is like the operating system of a computer, then the smallest cellular OS has just been written. Called Syn3.0, it encodes everything needed to make a viable, autonomously replicating cell.

Mycoplasma is a genus of bacteria that are the smallest known free-living... Read More

TWiV 383: A zillion Zika papers and a Brazilian


Hosts: Vincent RacanielloDickson DespommierAlan Dove and  Read More

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