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The Dawn of Proteomics

Frederick C. Neidhardt, F.G. Novy Distinguished University Professor, Emeritus, Department of Microbiology and Immunology, University of Michigan Medical School at Ann Arbor, authors a post at the Small Things Considered blog on the dawn of proteomics, the large-scale study of proteins, with a f... Read More

Oddly Microbial: 86 Million Year-Old Deep Seabed Mystery Cells

Life in a high-pressured environment with practically nothing to eat might be ok for high-fashion models, but it’s an unlikely lifestyle choice for a single cell whose usual overriding goal is to become two cells. Yet the largest living ecosystem on Earth—the deep biosphere—is comprised of micro... Read More

The Microbial Weltanschauung

The figure for the number of prokaryotic cells on the planet, roughly 5x1030, is considerably greater than that of the estimated number of stars in the firmaments (3x1023). These two numbers have one thing in common: they both grew hugely and rather suddenly in recent human history.

Click "s... Read More

TWiV 98 Letters

James writes:


I'm just writing to clarify my question about the production of the flu vaccine if one of the other seasonal strains was removed as there seemed to be a bit of confusion about the point of it.


As I understand it one of the biggest holdups in seas... Read More

Trust science, not scientists

Whether or not the retrovirus XMRV is a human pathogen has been debated since the virus was first described in 2006. The answer is now clear: the results of Blood XMRV Scientific Research Group, along with a partial retraction of the 2009 Science paper describing identification of the retrovirus... Read More

Genes, malevolent and beneficial pathogens and autoantibodies in HIV-1/AIDS

Certain viral infections are known to increase or decrease HIV-1 replication or viral load, perhaps by competing with the same receptors, or via immune and other effects.Many autoantibodies in HIV-1 infection also target the immune network and this may well contribute to pathology. Read More

World Tuberculosis Day 2009

Today is World Tuberculosis Day.

"World TB Day, 24 March 2009, is about celebrating the lives and stories of people affected by TB: women, men and children who have taken TB treatment; nurses; doctors; researchers; community workers--anyone who has contributed towards the global fight agains... Read More

Genome of arsenic bacterium sequenced

The genome nucleotide sequence has been determined of the bacterium GFAJ-1, which has been suggested to survive in high levels of arsenic and in fact incorporate arsenic into macromolecules. The sequence does not address the controversy over whether the bacterium can utilize arsenic. I suppose t... Read More

El podcast del Microbio Nº 233. Bacterias come-sushi (sushi-eater bacteria)



























El podcast del microbio Nº 233 summarize the findings by Handeman et al (Nature, 464: 908-912.) on the transfer of carbohydrate-... Read More

TWiV 153 Letters

Jim Pipas writes:


1. Geographic Breakdown. The data can be broken down by location if you download Table S2. It is in the last column. We didn't discuss the data by location because for this paper we took a single sample from each site. Thus, this is a snapshot of vir... Read More

ASM's Peer-Reviewed Collection of K-12 Outreach Classroom Activities

The American Society for Microbiology Committee on K-12 Education publishes peer-reviewed resources that convey important scientific concepts from the microbial world, such as microbial processes, methods used to study microorganisms and other general science topics. The activities are student-c... Read More

Aurintricarboxylic acid (ATA) may be an effective antiviral against Influenzaviruses

The hunt continues for novel antiviral agents especially against the pandemic H1N1 virus. In this article, a drug that has been used to fight HIV infection and vesicular stomatitis now appears to have the potential to block influenzavirus infection by inhibiting neuraminidase. This may be yet ... Read More

It's Raining Viruses

It’s true! Each year it rains viruses, more than a trillion of them per acre over thousands of forested acres in the USA. This is the work of the airborne arm of the USDA Forest Service, part of their efforts to reduce the devastation to hardwood forests caused by the imported gypsy moth, Lymant... Read More

A Giant Among Giants

Merry Youle from the Small Things Considered blog ponders the potential size a virus can be:

"With such fascinating stories being told by Mimivirus and the other giants, people are now looking for them in more environments. Modified techniques are called for, as those used previously to spot ... Read More

Collection of microbe-themed blogs and podcasts

A collection of links to blogs and podcasts that either focus entirely on microbes or partially on microbes. Other suggestions wanted. Read More

El podcast del Microbio Nº 230: Pequeña Micro-Pila de Energía (New Micro-Fuel Cell)



























El podcast del microbio Nº 230 summarize the work by Li et al. and published in Biotechnology Bioengineering about Microbial el... Read More

Tree of Life Blog: Overselling the microbiome award #2: The Marshall Protocol

A discussion of the "Marshall Protocol" which is a claimed treatment for all sorts of ailments. The article discusses how the MP backers suggests not only that microbes cause a wide diversity of ailments, but that a specific protocol can cure these ailments. The article discusses the lack of e... Read More

TWiV 160 Letters

Neva writes:


Hi fellas,


Great programs as always. I look forward to each one: TWIV, TWIM & TWIP. .....Lots of TWIT too. ;-)


Here is a list of top science apps forwarded by William Gunn on G+.


Mendeley and PLoS staff both vo... Read More

TWiV 55

Kevin writes:


Dear TWIVvers,


I was listening to TWIV episode #50, concerning the recent article from Ila Singh’s group about the prostate cancer – XMRV connection, on the same day the NY Times reported a study from Judy Mikowitz et al., finding an association between ... Read More

Comments on the “Synthetic Cell”

"The now famous announcement by the Venter group is based on their paper in Science entitled Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome. We applaud this work for its impressive technical achievement and we acknowledge its future potential. However, we find the ter... Read More
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