First, you may be asking yourself – Why viral bioinformatics? Good question! Although it’s true that much in the world of bioinformatics can be applied to all manner of protein and DNA sequences, there are a number of resources that are specific for viruses and there are a number of analyses tha... Read More
There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the p... Read More
This past February I was interviewed by the Australian Broadcasting Company on the topic of the Fouchier and Kawaoka experiments on avian influenza virus H5N1. The video, Building the Perfect Bug, has been released by Journeyman Pictures and includes interviews with S.T. Lai, Laurie Garrett, Mic... Read More
Looks like the polio outbreak in the Congo is pretty bad.
http://www.unicef.org/me... Read More
I think this image from www.3d4medical.com is great!
This is a cool app for the iPad. This would make a great pick of the week
Julian writes:<... Read More
The protein components of the plaques and tangles seen in the Alzheimer's disease brain offer a clue to the origins of the disease: It turns out that they are heavily enriched in human proteins used by herpes simplex during its life cycle: Many immune system related proteins are also found in th... Read More
Thanks again for all the effort and care you invest into your podcasts. I'm writing today to suggest a pick of the week: The Nature of Things with David Suzuki. Suzuki, one of Canada's scientist/rock-stars, hosts... Read More
The Public Library of Science's open access journals just release its 2009 June Progress Report in which they project "a publishing business model projected to be 100% self-sufficient in 2010."
"PLoS journals use a business model that recovers expenses — including administration of peer revie... Read More
El podcast del Microbio Nº174 and 175 are dedicated to Alice Catherine Evans, one of the first women microbiologists. Los ... Read More
What is a vaccine, and why do we need them? How do vaccines work, and how were they developed? In this lesson, students gauge their previous knowledge about vaccines. They then explore the history and biology of vaccines and create educational posters on the nature of vaccines and public opinion... Read More
Julian Davies, Professor emeritus at the University of British Columbia and a Fellow of the Royal Society, has authored a humorous post on the Small Things Considered blog on the various methods an attendee of a scientific meeting can employ to enhance "maximum satisfaction and poise" one gets o... Read More
This is a great article by Carl Zimmer in the NY Times (@carlzimmer on Twitter) about the evolution process of viruses.
"Some viruses use DNA, like we do, to encode their genes. Others, like the influenza virus, use single-strand RNA. But viruses all have one thing in common, said Roland Wolk... Read More
The second of two papers on avian influenza H5N1 virus that caused such a furor in the past year was published today in the journal Science. I have carefully read the paper by Fouchier and colleagues, and I assure you that it does not enable the production of a deadly biological weapon. The resu... Read More
Elio Schaechter of Small Things Considered has authored an interesting post today about the motility of bacteria, specifically Paenibacillus, although he does highlight several other strains that swarm, glide or twitch.
"Microbes get around. They can be carried by the wind, by insects, or by ... Read More
On the Small Things Considered blog, Michael Schmidt, Professor and Vice Chairman of Microbiology and Immunology at the Medical University of South Carolina, reviews a recent paper entitled "Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement" by Church and colleagu... Read More
I just returned from a 17-day, 3,000 km road trip with my family in Europe. When I travel I’m always on the lookout for virus-related information and I found some at the Deutsches Museum in Munich, Germany. This museum showcases science and technology – it has over 100,000 objects illustrating t... Read More
I have heard recently that some types of herpes virus may protect us from bacterial infections. This made me remember of myxomavirus, viral oncotherapy and how tumor cells have a compromised immune response. Do you think it is possi... Read More
Some time ago I emailed you about transcribing an episode of TWiV and have finally finished episode 60. Let me join the chorus of appreciative listeners in praise for your podcast! I've learned a lot from it I was inspired by your generosity... Read More
El podcast del Microbio Nº190 and 191 describes the recent metagenomic results that point towards the existence of a 4th do... Read More