There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the p... Read More
Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):
It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More
I think this image from www.3d4medical.com is great!
This is a cool app for the iPad. This would make a great pick of the week
Julian writes:<... Read More
Some time ago I emailed you about transcribing an episode of TWiV and have finally finished episode 60. Let me join the chorus of appreciative listeners in praise for your podcast! I've learned a lot from it I was inspired by your generosity... Read More
Frederick C. Neidhardt, F.G. Novy Distinguished University Professor, Emeritus, Department of Microbiology and Immunology, University of Michigan Medical School at Ann Arbor, authors a post at the Small Things Considered blog on the dawn of proteomics, the large-scale study of proteins, with a f... Read More
El podcast del Microbio Nº206 is dedicated to the recent discovery of stromatolites in deep of Antartic lake Untersee. El p... Read More
The figure for the number of prokaryotic cells on the planet, roughly 5x1030, is considerably greater than that of the estimated number of stars in the firmaments (3x1023). These two numbers have one thing in common: they both grew hugely and rather suddenly in recent human history.
Click "s... Read More
India has been free of polio for over one year. This is a remarkable accomplishment, considering that just 30 years ago the country recorded 200,000 cases of the disease annually, or one every three minutes. With polio endemic in two neighboring countries, Pakistan and Afghanistan, and in the mo... Read More
The hunt continues for novel antiviral agents especially against the pandemic H1N1 virus. In this article, a drug that has been used to fight HIV infection and vesicular stomatitis now appears to have the potential to block influenzavirus infection by inhibiting neuraminidase. This may be yet ... Read More
The National Foundation for Infectious Diseases (NFID)has announced the availability of two new resources designed to support pneumococcal disease prevention efforts on NFID’s website, Adultvaccination.org:
• a professional practice toolkit for healthcare professionals (HCPs)
Th... Read More
Certain viral infections are known to increase or decrease HIV-1 replication or viral load, perhaps by competing with the same receptors, or via immune and other effects.Many autoantibodies in HIV-1 infection also target the immune network and this may well contribute to pathology. Read More
Thanks again for all the effort and care you invest into your podcasts. I'm writing today to suggest a pick of the week: The Nature of Things with David Suzuki. Suzuki, one of Canada's scientist/rock-stars, hosts... Read More
Looks like the polio outbreak in the Congo is pretty bad.
http://www.unicef.org/me... Read More
Renowned influenza virologist Peter Palese has penned an opinion column for the science journal Nature in which he uses his experience in reconstructing the 1918 pandemic influenza virus strain to question the censoring of H5N1 results by the National Science Advisory Board for Biosecurity (NSAB... Read More
TWiV listeners have spent their valuable time writing comments about the podcast on iTunes, and it's a shame that most people don't see them. I'm putting them here as a way of thanking them for their time, and for listening. This i... Read More
The American Society for Microbiology Committee on K-12 Education publishes peer-reviewed resources that convey important scientific concepts from the microbial world, such as microbial processes, methods used to study microorganisms and other general science topics. The activities are student-c... Read More
El podcast del Microbio Nº200 is dedicated to the memory of Baruch Blumberg (1925-2011). El podcast del Microbio Nº200 está... Read More
Merry Youle of Small Things Considered has authored a post that looks at Thiomargarita spp.
"Non-motile Thiomargarita was first discovered in 1999 off the Namibian coast, thus was named T. namibiensis. Its cells are large spheres, arranged in chains, each chain enclosed in a mucous sheath. Av... Read More
Life in a high-pressured environment with practically nothing to eat might be ok for high-fashion models, but it’s an unlikely lifestyle choice for a single cell whose usual overriding goal is to become two cells. Yet the largest living ecosystem on Earth—the deep biosphere—is comprised of micro... Read More
Whether or not the retrovirus XMRV is a human pathogen has been debated since the virus was first described in 2006. The answer is now clear: the results of Blood XMRV Scientific Research Group, along with a partial retraction of the 2009 Science paper describing identification of the retrovirus... Read More