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Norton Zinder, 1928-2012

Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More

TWiV 162 Letters

Sarah writes:


Hello to the TWiV crew,


Here are a couple of picks I thought would be good for provoking thought and generating discussion...


While working on a project, I came across some papers attempting to define what "critical thinking" means. I app... Read More

TWiV 163 Letters

Ronnie writes:


Hello Professor Vincent,


First of all, thank you for your wonderful podcasts! I'm a CFS sufferer and also a student Applied Science so I'm interested in many of the topics discussed for those two reasons and always learning new things.


I... Read More

The Rise of Genomic Superspreaders

One hundred million years ago the earth’s climate was much warmer than today and vast inland seas stretched across entire continents. The land was dominated by charismatic megafauna that would one day serve as inspiration for Sir Arthur Conan Doyle’s novel The Lost World. This period is commonly... Read More

Genome Wide Manipulation of the Bacterial Chromosome in Vivo

On the Small Things Considered blog, Michael Schmidt, Professor and Vice Chairman of Microbiology and Immunology at the Medical University of South Carolina, reviews a recent paper entitled "Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement" by Church and colleagu... Read More

Podcast del Microbio Nº190 y 191. El Cuarto Dominio (The Fourth Domain)



























El podcast del Microbio Nº190 and 191 describes the recent metagenomic results that point towards the existence of a 4th do... Read More

What Happened to Our Friendly Enterococci?

Enterococci had been generally regarded as benign commensals, a part of our healthy intestinal microbiota. They were even invited in, being used as probiotics. But then, in the late 1970s, the first multiple drug-resistant strains appeared, and vancomycin-resistant strains followed in 1981. In r... Read More

TWiV 140 Letters

from @Lafrenchfille on Twitter:


French listen to your very cool podcast. So I can confirm, "Mimi" is french !


Peter writes:


Regarding the podcasting advice from the fellow in Israel.


Explain st... Read More

TWiV 90 Letters

Eric writes:


Hi Vincent,


After 86 episodes of TWiV, I am still loving every minute of the podcast and I am constantly impressed with how much I learn. For example, I have been mentoring an undergraduate student in the lab and we have had a rough two week stret... Read More

El podcast del Microbio Nº 243: Sexo, neardentales y sistema inmune (Sex, neandertals and immune system)



























El podcast del microbio Nº 243 summarize the Science article by Abi-Rached et al. about the interbreeding between neandhertal an... Read More

Influenza H5N1 virus versus ferrets, round two

The second of two papers on avian influenza H5N1 virus that caused such a furor in the past year was published today in the journal Science. I have carefully read the paper by Fouchier and colleagues, and I assure you that it does not enable the production of a deadly biological weapon. The resu... Read More

The Lazarus virus

There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the p... Read More

TWiV 115 Letters

Vinayaka writes:


Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):


It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More

El podcast del microbio Nº 109: Derrames de petróleo



























The Nº 109 of the "El podcast del microbio" deals with the recent oil spill in the Gulf of Mexico caused by the accident in the Deepwater Hor... Read More

TWiV 101 Letters

Russ writes:


I think this image from www.3d4medical.com is great!


This is a cool app for the iPad. This would make a great pick of the week


Russ


Julian writes:<... Read More

TWiV 139 Letters

Norma writes:


Some time ago I emailed you about transcribing an episode of TWiV and have finally finished episode 60. Let me join the chorus of appreciative listeners in praise for your podcast! I've learned a lot from it I was inspired by your generosity... Read More

El podcast del Microbio Nº 206. Estromatolitos antárticos



























El podcast del Microbio Nº206 is dedicated to the recent discovery of stromatolites in deep of Antartic lake Untersee. El p... Read More

The Dawn of Proteomics

Frederick C. Neidhardt, F.G. Novy Distinguished University Professor, Emeritus, Department of Microbiology and Immunology, University of Michigan Medical School at Ann Arbor, authors a post at the Small Things Considered blog on the dawn of proteomics, the large-scale study of proteins, with a f... Read More

The Microbial Weltanschauung

The figure for the number of prokaryotic cells on the planet, roughly 5x1030, is considerably greater than that of the estimated number of stars in the firmaments (3x1023). These two numbers have one thing in common: they both grew hugely and rather suddenly in recent human history.

Click "s... Read More

Aurintricarboxylic acid (ATA) may be an effective antiviral against Influenzaviruses

The hunt continues for novel antiviral agents especially against the pandemic H1N1 virus. In this article, a drug that has been used to fight HIV infection and vesicular stomatitis now appears to have the potential to block influenzavirus infection by inhibiting neuraminidase. This may be yet ... Read More

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