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TWiV 155 Letters

Kim writes:


To the TWiVerati Intelligencia,


Each week you begin your show with the tagline, "This Week in Virology: The podcast about viruses, the kind that make you sick."


I recognize that viruses have been responsible for some of the biggest epidemic... Read More

Frank Fenner, MD, 1914-2010

Australian virologist Frank Fenner, MD was born in Ballarat, Victoria in 1914. He earned a Doctor of Medicine in 1942 at the University of Adelaide, and from 1940 – 1946 he worked on the malaria parasite in Egypt and Papua New Guinea as an officer in the Australian Army Medical Corps. He subsequ... Read More

Norton Zinder, 1928-2012

Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More

XMRV and CFS – It’s not the end

Yesterday the Chicago Tribune published my reaction to the four papers on the retrovirus XMRV published this week in the journal Retrovirology. I was quoted as saying ”These four papers are probably the beginning of the end of XMRV and CFS”. I wish to retract this statement and explain my reason... Read More

Genome Wide Manipulation of the Bacterial Chromosome in Vivo

On the Small Things Considered blog, Michael Schmidt, Professor and Vice Chairman of Microbiology and Immunology at the Medical University of South Carolina, reviews a recent paper entitled "Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement" by Church and colleagu... Read More

10 Genes, Furiously Evolving

This is a great article by Carl Zimmer in the NY Times (@carlzimmer on Twitter) about the evolution process of viruses.

"Some viruses use DNA, like we do, to encode their genes. Others, like the influenza virus, use single-strand RNA. But viruses all have one thing in common, said Roland Wolk... Read More

Building the perfect bug

This past February I was interviewed by the Australian Broadcasting Company on the topic of the Fouchier and Kawaoka experiments on avian influenza virus H5N1. The video, Building the Perfect Bug, has been released by Journeyman Pictures and includes interviews with S.T. Lai, Laurie Garrett, Mic... Read More

Microbial Movers - A Small Things Considered Post

Elio Schaechter of Small Things Considered has authored an interesting post today about the motility of bacteria, specifically Paenibacillus, although he does highlight several other strains that swarm, glide or twitch.

"Microbes get around. They can be carried by the wind, by insects, or by ... Read More

Whole genome sequence of Borrelia burgdorferi...

Human Lyme disease is caused by a number of related Borrelia burgdorferi sensu lato species. We report here the complete genome sequence of Borrelia sp. isolate SV1 from Finland. Read More

The dwindling American science majors

According to the New York Times (Why Science Majors Change Their Minds), the decline in the number of science majors in the United States has come about in part because the subject matter is too difficult. If this explanation is true, then we have not properly prepared these students in grades K... Read More

The Rise of Genomic Superspreaders

One hundred million years ago the earth’s climate was much warmer than today and vast inland seas stretched across entire continents. The land was dominated by charismatic megafauna that would one day serve as inspiration for Sir Arthur Conan Doyle’s novel The Lost World. This period is commonly... Read More

TWiV 139 Letters

Norma writes:


Some time ago I emailed you about transcribing an episode of TWiV and have finally finished episode 60. Let me join the chorus of appreciative listeners in praise for your podcast! I've learned a lot from it I was inspired by your generosity... Read More

Health Alert Map Mash-up with Infectious Disease

This is a really cool Google Maps mash up that geo-locates breaking health news on a map. You can sort by official government announcements, news wires, infectious disease types, zoom to countries, local areas and more. Great for looking at Swine Flu reporting as it happens. Read More

Viral bioinformatics: Introduction + Homology

First, you may be asking yourself – Why viral bioinformatics? Good question! Although it’s true that much in the world of bioinformatics can be applied to all manner of protein and DNA sequences, there are a number of resources that are specific for viruses and there are a number of analyses tha... Read More

PLoS Journals Projected to be 100% Self-Sufficient by 2010

The Public Library of Science's open access journals just release its 2009 June Progress Report in which they project "a publishing business model projected to be 100% self-sufficient in 2010."

"PLoS journals use a business model that recovers expenses — including administration of peer revie... Read More

Happy as a clam? Maybe not.

The expression “Happy as a Clam” comes with new meaning as hepatitis A virus has been detected in clams, mussels, and oysters in markets for human consumption. As bivalve shellfish are excellent bio-accumulators of contaminants and chemicals, it is no surprise that they also harbor waterborne vi... Read More

TWiV 98 Letters

James writes:


I'm just writing to clarify my question about the production of the flu vaccine if one of the other seasonal strains was removed as there seemed to be a bit of confusion about the point of it.


As I understand it one of the biggest holdups in seas... Read More

The Three Faces of Thiomargarita

Merry Youle of Small Things Considered has authored a post that looks at Thiomargarita spp.

"Non-motile Thiomargarita was first discovered in 1999 off the Namibian coast, thus was named T. namibiensis. Its cells are large spheres, arranged in chains, each chain enclosed in a mucous sheath. Av... Read More

El Podcast del Microbio Nº 174 y 175. La Historia de Alice Catherine Evans. /The Story of Alice Catherine Evans)



























El podcast del Microbio Nº174 and 175 are dedicated to Alice Catherine Evans, one of the first women microbiologists. Los ... Read More

Alzheimer''s disease plaques and tangles: Repositories of a herpes simplex/immune system battle leading to neuronal destruction

The protein components of the plaques and tangles seen in the Alzheimer's disease brain offer a clue to the origins of the disease: It turns out that they are heavily enriched in human proteins used by herpes simplex during its life cycle: Many immune system related proteins are also found in th... Read More
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