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Automating the survey of protein locations: the trials and tribulations

An article by Alan Derman, Project Scientist in Joe Pogliano’s lab at the University of California at San Diego, published on the Small Things Considered blog presents a point-by-point analysis of a paper "Quantitative genome-scale analysis of protein localization in an asymmetric bacterium" pub... Read More

Conserved amino acid markers from past influenza pandemic strains

A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More

TWiV 155: XXII Brazilian National Virology Meeting

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Hosts: Vincent Racaniello, Grant McFadden, Eurico de A... Read More

El podcast del Microbio Nº 217. La sepia y la bacteria (the squid and the bacteria)



























El podcast del Microbio Nº217 describes the symbiosis between the squid Euprymna scolopes and the bacteria Vibrio fischeri.... Read More

XMRV and CFS – It’s not the end

Yesterday the Chicago Tribune published my reaction to the four papers on the retrovirus XMRV published this week in the journal Retrovirology. I was quoted as saying ”These four papers are probably the beginning of the end of XMRV and CFS”. I wish to retract this statement and explain my reason... Read More

David and Goliath: How one cytokine may take down influenza

Recent research has suggested a new method of flu prevention and treatment: the administration of granulocyte macrophage-colony stimulating factor (GM-CSF) to the lungs of mice significantly reduced flu symptoms and prevented mortality after a lethal dose of influenza virus. GM-CSF helps the bod... Read More

Are there viruses of arsenic-utilizing bacteria?

A salt-loving (halophilic) bacterium which can grow in medium containing arsenic instead of phosphorus has been selected from the microbial community of Mono Lake in California. Arsenic (As) is a chemical analog of phosphorus and is usually toxic because it can enter metabolic pathways in the pl... Read More

A mad cow in America

A dairy cow in California is the fourth known American case of mad cow disease, which is caused by prions, infectious agents composed only of protein (the story hit the press the day after my lecture on this type of illness). Unlike viruses, prions have no nucleic acid and no protective coat. Bu... Read More

Cryptic Life in the Antarctic Dry Valleys

Small Things Considered co-blogger Merry Youle has a post about the diversity of life in McKelvey Valley, a broad, glacially-carved pass just west of McMurdo Sound in Antarctica. Her writing is inspired in part by a recent paper from the University of Hong Kong (See Read More

TWiV 150: Contaminated

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Hosts: Vincent RacanielloR... Read More

TWiV 160: Moore tumor viruses

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Hosts: Vincent Racaniello, R... Read More

Is Vilyuisk encephalitis a viral disease?

A type of human encephalitis – an infection of the brain – has been known to affect the indigenous people living in the Sakha Republic of Russia since the mid-1800s. The available clinical and epidemiological evidence suggests that the disease is caused by a pathogen, but proving this has been d... Read More

TWiV 149 Letters

John writes:


Re the letter you got about a Spanish version of TWIV: ASM already has a nice Spanish microbiology podcast, called Mundos de los Microbios. Your TWIM co-host Elio has been on that podcast at least once that I’ve heard. Perhaps you could p... Read More

El podcast del Microbio Nº194. Algas para limpiar un desastre (Algae for nuclear clean-up)



























El podcast del Microbio Nº194 is about the recent observation that the algae Closterium moniliferum could remove strontium... Read More

Interesting Rhinovirus Study + Bonus Chicken Soup Recipe

This 2000 paper, published in Chest, shows that chicken soup is capable of inhibiting neutrophil chemotaxis in vitro, thus providing some evidence for the soup's traditional role as a home cure for respiratory infections.

Helpfully, the soup recipe used in the study is also included. And it ... Read More

TWiV 173 Letters

Judi writes:


A listener pick - since I know you all really enjoy the visualization of science!


http:... Read More

A bad day for science

The virologists who carried out the contentious experiments on influenza H5N1 transmission in ferrets have agreed to remove certain details from their manuscript, according to ScienceInsider. This is a bad day for virology, and for science in general. The decision by the NSABB sets a precedent f... Read More

TWiV 112 Letters

Jennie writes:


I love your show very much and this is not my first comment. I load firewood and paint as I listen to you guys, thanks so much for the inspiration over what is becoming years. I'm not an audio learner, though my mind is quite stimulated by what I hear. ... Read More

Propose a Topic for asm2012 - 112th General Meeting of ASM

Are you interested in proposing an interdisciplinary topic with maximum appeal? Do you have an idea for a core colloquium or symposium of scientific significance? ASM's General Meeting Program Committee is soliciting suggestions to help build the program for asm2012 in San Francisco, June 16-1... Read More

Finding the key to strengthening the immune response to chronic infections

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as s... Read More

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