First, I love your podcasts.
You guys are constantly grousing about the lack of research funding.
I was curious.
NIH, funding has risen every year since 2000, from $17B to the current $31B (supports 325,000 researchers)
NSF... Read More
El podcast del Microbio Nº217 describes the symbiosis between the squid Euprymna scolopes and the bacteria Vibrio fischeri.... Read More
Hi Dr Racaniello,
I am a long time listener of TWIV and really enjoy the informal scientific discussions. I listen to TWIV while working in the lab and am trying to catch up on TWIM and TWIP episodes too.
I have been dill... Read More
Hello People of TWIV!
Thanks for all the information you give and how you make me think. I really liked your discussions on TWIV 136 - exit XMRV, not as much for the science ( which was cool) but for the discussio... Read More
Recent research has suggested a new method of flu prevention and treatment: the administration of granulocyte macrophage-colony stimulating factor (GM-CSF) to the lungs of mice significantly reduced flu symptoms and prevented mortality after a lethal dose of influenza virus. GM-CSF helps the bod... Read More
The epidemiology episode with Michael Walsh was great. I loved the philosophical detour into counterfactual statements, time travel, and the meaning of causation. TWiV may indeed be viral, but from listening to it I fee... Read More
An article by Alan Derman, Project Scientist in Joe Pogliano’s lab at the University of California at San Diego, published on the Small Things Considered blog presents a point-by-point analysis of a paper "Quantitative genome-scale analysis of protein localization in an asymmetric bacterium" pub... Read More
A type of human encephalitis – an infection of the brain – has been known to affect the indigenous people living in the Sakha Republic of Russia since the mid-1800s. The available clinical and epidemiological evidence suggests that the disease is caused by a pathogen, but proving this has been d... Read More
After 86 episodes of TWiV, I am still loving every minute of the podcast and I am constantly impressed with how much I learn. For example, I have been mentoring an undergraduate student in the lab and we have had a rough two week stret... Read More
A dairy cow in California is the fourth known American case of mad cow disease, which is caused by prions, infectious agents composed only of protein (the story hit the press the day after my lecture on this type of illness). Unlike viruses, prions have no nucleic acid and no protective coat. Bu... Read More
A laboratory in the Netherlands has identified a lethal influenza H5N1 virus strain that is transmitted among ferrets. These findings are under review by the National Science Advisory Board for Biosecurity (NSABB) to ensure that they do not constitute a threat to human health. Meanwhile both the... Read More
Rich Condit found an article highly critical of the original Wakefield study (claiming a link between MMR vaccine and autism) which was published in the same issue of Lancet. He asked the publisher, Elsevier, to open up the article to non-subscribers so he could recommend it as a pick of the wee... Read More
A second virophage has been identified. The name does not signify a virus that infects another virus – it means virus eater.
Small Things Considered co-blogger Merry Youle has a post about the diversity of life in McKelvey Valley, a broad, glacially-carved pass just west of McMurdo Sound in Antarctica. Her writing is inspired in part by a recent paper from the University of Hong Kong (See Read More
A salt-loving (halophilic) bacterium which can grow in medium containing arsenic instead of phosphorus has been selected from the microbial community of Mono Lake in California. Arsenic (As) is a chemical analog of phosphorus and is usually toxic because it can enter metabolic pathways in the pl... Read More
This is a great online children's book about the role of bacteria in our lives by Dr. Mel Rosenberg for ages 3+. Read More
When infection with hepatitis C virus goes from acute to chronic, severe liver disease may occur which requires organ transplantation. Nearly 200 million people are chronically infected with HCV, necessitating approaches to preventing and treating infections. No HCV vaccine is available, and cur... Read More
Aaron J. Shatkin was well known for his work on reoviruses beginning in the 1960s in his laboratory at the Roche Institute of Molecular Biology in Nutley, NJ and then at Rutgers University. He was among the first to appreciate that virus particles contained many different enzymes, such as RNA po... Read More
Science writer Carl Zimmer writes a masterful blog piece tracing the history of the study of ecosystems, from lakes to the human microbiome. Just one interesting fact: In their lifetimes, individual humans will produce about five elephants worth of microbes. Read More
Yesterday the Chicago Tribune published my reaction to the four papers on the retrovirus XMRV published this week in the journal Retrovirology. I was quoted as saying ”These four papers are probably the beginning of the end of XMRV and CFS”. I wish to retract this statement and explain my reason... Read More