After 86 episodes of TWiV, I am still loving every minute of the podcast and I am constantly impressed with how much I learn. For example, I have been mentoring an undergraduate student in the lab and we have had a rough two week stret... Read More
Looks like the polio outbreak in the Congo is pretty bad.
http://www.unicef.org/me... Read More
Some viruses that infect bacteria (bacteriophages) deliver their DNA into the host cell with an amazing injection machine. The tailed bacteriophages (such as T4, illustrated) store their DNA in a capsid attached to a long tail tube that is surrounded by a sheath. At the bottom of the tube is a b... Read More
The novel human retrovirus XMRV has been associated with prostate cancer and chronic fatigue syndrome. The nucleotide sequence of XMRV isolated from humans indicates that the virus is nearly identical with XMRV produced from a human prostate tumor cell line called 22Rv1. This cell line was deriv... Read More
Hi Vince and the rest of the TWIV-cast!
You might have come across this news already, but it would be interesting to hear the TWIV gang's take on this study done by Fouchier's group from the Netherlands.
Recent research has suggested a new method of flu prevention and treatment: the administration of granulocyte macrophage-colony stimulating factor (GM-CSF) to the lungs of mice significantly reduced flu symptoms and prevented mortality after a lethal dose of influenza virus. GM-CSF helps the bod... Read More
I think this image from www.3d4medical.com is great!
This is a cool app for the iPad. This would make a great pick of the week
Julian writes:<... Read More
Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):
It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More
This teleconference is sponsored by the American Society for Microbiology and will review the history and importance of methicillin-resistant Staphylococcus aureus (MRSA) with a primary focus on the emergence of community-associated MRSA (CA-MRSA). The phenotypic and molecular identification of ... Read More
First, I love your podcasts.
You guys are constantly grousing about the lack of research funding.
I was curious.
NIH, funding has risen every year since 2000, from $17B to the current $31B (supports 325,000 researchers)
NSF... Read More
An article by Alan Derman, Project Scientist in Joe Pogliano’s lab at the University of California at San Diego, published on the Small Things Considered blog presents a point-by-point analysis of a paper "Quantitative genome-scale analysis of protein localization in an asymmetric bacterium" pub... Read More
A laboratory in the Netherlands has identified a lethal influenza H5N1 virus strain that is transmitted among ferrets. These findings are under review by the National Science Advisory Board for Biosecurity (NSABB) to ensure that they do not constitute a threat to human health. Meanwhile both the... Read More
Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so ... Read More
A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More
Small Things Considered co-blogger Merry Youle has a post about the diversity of life in McKelvey Valley, a broad, glacially-carved pass just west of McMurdo Sound in Antarctica. Her writing is inspired in part by a recent paper from the University of Hong Kong (See Read More
This is a great online children's book about the role of bacteria in our lives by Dr. Mel Rosenberg for ages 3+. Read More
Hello TWiV hosts,
I'm currently working as a technician in the biochemistry and molecular biophysics department at Columbia, having just received my BA from here in the Spring. First of all, I'd like to join the chorus of praises ... Read More
Aaron J. Shatkin was well known for his work on reoviruses beginning in the 1960s in his laboratory at the Roche Institute of Molecular Biology in Nutley, NJ and then at Rutgers University. He was among the first to appreciate that virus particles contained many different enzymes, such as RNA po... Read More
The third annual installment of my virology course at Columbia University, Biology W3310, has begun, and all the lectures will be available online. Read More
A dairy cow in California is the fourth known American case of mad cow disease, which is caused by prions, infectious agents composed only of protein (the story hit the press the day after my lecture on this type of illness). Unlike viruses, prions have no nucleic acid and no protective coat. Bu... Read More