I've been having an enjoyable time on my commute lately catching up with TWiV. Today I listened to #26 (Poxviruses), which included a discussion of Tysabri and PML. I work at Millipore which sells many products that go into a MAb production train, includ... Read More
Some viruses that infect bacteria (bacteriophages) deliver their DNA into the host cell with an amazing injection machine. The tailed bacteriophages (such as T4, illustrated) store their DNA in a capsid attached to a long tail tube that is surrounded by a sheath. At the bottom of the tube is a b... Read More
If you know anything about snakes you might be familiar with snake inclusion body disease, or IBD. This transmissible and fatal disease affects snakes of a variety of species but has been best studied in boas. The name comes from the presence of large masses (inclusions) in the cytoplasm of cell... Read More
Glenn Rall, a virologist at Fox Chase Cancer Center, sent me the following note:
Baruch S. Blumberg, Nobel Laureate in 1976 for discovery of Hepatitis B (and the eventual development of the vaccine, which probably has saved hundreds of thousands of lives since its introduction), died this pas... Read More
In TWIV 173, you talked about a study on antibody levels to bird flu (H5N1) in various populations, and related this to infections that don't cause serious enough illness to send someone to the hospital, or perhaps to get them teste... Read More
The novel human retrovirus XMRV has been associated with prostate cancer and chronic fatigue syndrome. The nucleotide sequence of XMRV isolated from humans indicates that the virus is nearly identical with XMRV produced from a human prostate tumor cell line called 22Rv1. This cell line was deriv... Read More
Does the same concern that you discussed with suppressed immunity after a transplant apply to folks who undergo chemotherapy for cancer? (re strongyloides)
Hi V... Read More
This episode: Our archaeal ancestors may have been more important to us than bacterial!
Hello fellow virus lovers,
I first want to comment about Vincent's pick of the week a few weeks back, the book "Polio" by David Oshinsky. I am currently studying poliovirus in Julie Pfeiffer's lab (as you revealed many moons ago with a previous ... Read More
Re the letter you got about a Spanish version of TWIV: ASM already has a nice Spanish microbiology podcast, called Mundos de los Microbios. Your TWIM co-host Elio has been on that podcast at least once that I’ve heard. Perhaps you could p... Read More
Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so ... Read More
The CDC has just published "Preparing for the Flu: A Communication Toolkit for Child Care and Early Childhood Programs." A .pdf document that provides information and communication resources to help center-based and home-based child care programs, Head Start programs, and other early childhood p... Read More
This 2000 paper, published in Chest, shows that chicken soup is capable of inhibiting neutrophil chemotaxis in vitro, thus providing some evidence for the soup's traditional role as a home cure for respiratory infections.
Helpfully, the soup recipe used in the study is also included. And it ... Read More
A listener pick - since I know you all really enjoy the visualization of science!
Dear TWiV hosts,
I'm sure you've already heard about this, but I was curious what your take on this study is.
I love your show very much and this is not my first comment. I load firewood and paint as I listen to you guys, thanks so much for the inspiration over what is becoming years. I'm not an audio learner, though my mind is quite stimulated by what I hear. ... Read More
One of two papers on avian influenza H5N1 virus that caused such a furor in the past six months was published today in the journal Nature. I have read it, and I can assure you that the results do not enable the construction of a deadly biological weapon. Instead, they illuminate important requir... Read More
A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More