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Getting Started with MicrobeWorld

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Detecting viral proteins in infected cells or tissues by immunostaining

Many virological techniques are based on the specificity of the antibody-antigen reaction. Examples in our virology toolbox include western blot analysis and ELISA. While very useful, these methods cannot be used to visualize viral proteins in infected cells or tissues. To do that we must turn t... Read More

TWiV 173 Letters

Judi writes:


A listener pick - since I know you all really enjoy the visualization of science!


http:... Read More

TWiP 26 Letters

Jim writes:

Prof Dickson,


Does the same concern that you discussed with suppressed immunity after a transplant apply to folks who undergo chemotherapy for cancer? (re strongyloides)


Jim
Smithfield, VA


Spencer writes:


Hi V... Read More

TWiV 177 Letters

John writes:


Dear TWIVvers,


In TWIV 173, you talked about a study on antibody levels to bird flu (H5N1) in various populations, and related this to infections that don't cause serious enough illness to send someone to the hospital, or perhaps to get them teste... Read More

TWiV 165 Letters

Justin writes:


Are you, Alan Dove and Prof. Racaniello, saying you think Mikovits and/or others on the Lombardi paper lied about the results or blinding? I think circumspection is a natural human reaction to the allegations of theft that have been made against Dr. Mik... Read More

TWiV 160: Moore tumor viruses

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, R... Read More

WHO decides to keep smallpox stocks....for now

The World Health Organization has decided not to recommend destruction of the remaining stocks of smallpox virus. This debate has been ongoing since 1980, when the disease was declared eradicated. WHO has indicated that no new experiments on smallpox virus will be permitted, only conclusion of o... Read More

TWiV 142 Letters

TWiV 142


Marshall writes:


Dear TWiV hosts,


I'm sure you've already heard about this, but I was curious what your take on this study is.


Read More

Interesting Rhinovirus Study + Bonus Chicken Soup Recipe

This 2000 paper, published in Chest, shows that chicken soup is capable of inhibiting neutrophil chemotaxis in vitro, thus providing some evidence for the soup's traditional role as a home cure for respiratory infections.

Helpfully, the soup recipe used in the study is also included. And it ... Read More

The New Scientist's Swine Flu Resources Page

The New Scientist has put together a nice collection of articles and information about the swine flu on it's site. Read More

TWiV 180 Letters

Rohit writes:


Hi Dr Racaniello,


I am a long time listener of TWIV and really enjoy the informal scientific discussions. I listen to TWIV while working in the lab and am trying to catch up on TWIM and TWIP episodes too.


I have been dill... Read More

Baruch S. Blumberg, MD, 1925-2011

Glenn Rall, a virologist at Fox Chase Cancer Center, sent me the following note:

Baruch S. Blumberg, Nobel Laureate in 1976 for discovery of Hepatitis B (and the eventual development of the vaccine, which probably has saved hundreds of thousands of lives since its introduction), died this pas... Read More

A spike for piercing the cell membrane

Some viruses that infect bacteria (bacteriophages) deliver their DNA into the host cell with an amazing injection machine. The tailed bacteriophages (such as T4, illustrated) store their DNA in a capsid attached to a long tail tube that is surrounded by a sheath. At the bottom of the tube is a b... Read More

TWiV 172 Letters

Greg writes:


Dear TWiV,


The epidemiology episode with Michael Walsh was great. I loved the philosophical detour into counterfactual statements, time travel, and the meaning of causation. TWiV may indeed be viral, but from listening to it I fee... Read More

Tiny snow-makers

The Judges' Choice for The Scientist magazine's 2011 Labby Multimedia Awards is this cute video on how microbes are essential for snow formation.













Read More

TWiV 143 Letters



Judi writes:


Hello People of TWIV!


Thanks for all the information you give and how you make me think. I really liked your discussions on TWIV 136 - exit XMRV, not as much for the science ( which was cool) but for the discussio... Read More

XMRV is a recombinant virus from mice

The novel human retrovirus XMRV has been associated with prostate cancer and chronic fatigue syndrome. The nucleotide sequence of XMRV isolated from humans indicates that the virus is nearly identical with XMRV produced from a human prostate tumor cell line called 22Rv1. This cell line was deriv... Read More

TWiV 152: Viromes in the effluence of society

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Al... Read More

Kawaoka paper published on aerosol transmission of H5 influenza virus in ferrets

One of two papers on avian influenza H5N1 virus that caused such a furor in the past six months was published today in the journal Nature. I have read it, and I can assure you that the results do not enable the construction of a deadly biological weapon. Instead, they illuminate important requir... Read More

India polio-free for one year

A year has passed since the last reported case of poliomyelitis in India, which occurred on 13 January 2011 in a two year old girl in Howrah, West Bengal. Read More
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