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C. elegans micro-injection

This video shows the process of injecting a a construct with gene manipulated DNA into a C. elegans worm. The outcome in this case was the rolling worm with the green fluorescent protein in it that localized to the body wall muscle, giving the worm the four green stripes along his body. Read More

Green Algae

The most clearly plant-like algae, this species gets its namesake hue from high levels of chlorophyll.


Their cell walls are made up of cellulose, the same material that makes up the cell walls in larger, multicellular plants. Like plants, they store the food they make through photosyn... Read More

TWiV special: MERS-coronavirus in dromedary camels

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Host: Vincent Racaniello


Guests: Read More

TWiV 414: Zika in the guys with Diamond

Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication.


Hosts:  Read More

Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More

MMP #16: Insights into Toxoplasma gondii parasites

Host: Jeff Fox with special guest, Emma Wilson.


Emma H. Wilson of the University of California, Riverside, talks with Jeff Fox about efforts, with her collaborators to determine more precisely how Toxoplasma gondii parasites disrupt the mammalian brain—in this case, the brains of mice... Read More

Predicting UTI antibiotic resistance

By now, the news of a colistin-resistant E. coli isolate from a patient in the United States is widespread, with many major news sources covering the story. Most outlets highlighted the ease of future transfer of the plamid-borne mcr-1 gene between bacteria, the role of agricultural antibiotic u... Read More

TWiM #146: Viral arbitrium

Vincent, Elio and Michael discuss the finding of a prion in bacteria, and how communication between bacteria guides the decision between lysis and lysogeny.


Hosts Vincent Racaniello Read More

TWiV 244: Back in the CVVR

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Hosts: Vincent Racaniello and Read More

Monitoring H1N1 with Twitter--interview with Philip Polgreen of the University of Iowa

Micro-blogging via Twitter is being evaluated as a means for tracking infectious diseases. The 2009 outbreak of H1N1 provided them an opportunity for testing Twitter as an approach for tracking disease outbreaks. From the end of April, researchers at the University of Iowa began collecting Twitt... Read More

TWiV 304: Given X, solve for EBOV

 The TWiV team consults an epidemiologist to forecast the future scope of the Ebola virus epidemic in West Africa.


Hosts: Vincent Racaniello Read More

XMRV infection is enhanced by prostatic protein fragments

Fragments of an abundant protein produced by the prostate form amyloid fibrils that enhance infection of cells by human immunodeficiency virus type 1. These fibrils, called semen-derived enhancer of virus infection (SEVI), have been found to boost infection of prostate cells by the retrovirus XM... Read More

TWiV 413: Partnerships not Parachutes

From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases.


Hosts:  Read More

TWiV 222: Jumpin' Jack Flash, it's a GAS GAS GAS

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Hosts: Vincent Racaniello, Rich Condit Read More

An Ebolavirus vaccine in Africa

An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More

TWiM #141: Nutritional immunity and polymicrobial infections

Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.


Hosts: Vincent Racaniello, ... Read More

Art and Microbiology

A collection of funny images about microbiology. Although the text is in Spanish language, it can be easily understood. Read More

Gut microbes influence defense against influenza

The bacteria in our intestines outnumber by tenfold the 100 trillion cells that comprise the human body. This gut microbiota has many beneficial functions, including the production of vitamins and hormones, fermentation, regulation of gut development, and shaping intestinal immune responses. The... Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More

TWiV 402: The plight of the bumblebee

Polio returns to Nigeria, Zika virus spreads in Miami, and virus infection of plants attracts bumblebees for pollination, from the virus gentlepeople at TWiV.


Hosts: Vincent Racaniello Read More

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