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Motility mechanism of malaria pathogens explained

How do one-celled parasites move from the salivary gland of a mosquito through a person's skin into red blood cells? What molecular mechanisms form the basis for this very important movement of the protozoa? A team of researchers headed by Dr. Friedrich Frischknecht, head of a research group at ... Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

TWiV 309: Ebola email

The TWiVocytes answer questions about Ebola virus, including mode of transmission, quarantine, incubation period, immunity, and much more.


 Hosts: Vincent Racaniello Read More

Human infections with influenza H5N1 virus: How many?

The lethality of avian influenza H5N1 infections in humans has been a matter of extensive debate. The >50% case fatality rate established by WHO is high, but the lethality of the virus might be lower if there are many infections accompanied by mild or no disease. One way to answer this question ... Read More

TWiM 103 Letters

Bailey writes:


Hey Vincent, Elio, Michele and Michael!


I'm a first year microbiology graduate student at UC Berkeley and an avid listener of twim. Elio's snippet from the most recent podcast reminded me of a personal anecdote that might be useful to share with... Read More

TWiV 332: Vanderbilt virology

Host: Vincent Racaniello


Guests: Seth BordensteinJames Crowe... Read More

TWiV 289: Vinny and the capsids

Vinny and the capsids answer listener questions about the definition of life, state vaccination laws, the basic science funding problem, viral ecology, inactivation of viruses by pressure, and much more.


Hosts:  Read More

BacterioFiles Micro Edition 30 - Successful Synthetic Sequences

This episode: Artificial proteins actually function in bacteria!


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TWiP 77 letters

Andy writes:


Dear Professors,


I have been following TWIP for several years. I am a software engineer and parasitology is only an avocation. As an undergraduate in the early 80's I discovered my love of history of science and ecology, although I continued the p... Read More

TWiV 329: Pox in the balance

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

8th grader petri dishes - seeking help to identify colonies

I did a study of hand washing and hand sanitizer. Is anyone on the list willing to help me identify what grew from my unwashed and even washed hands? I attach three photos representing the yellow, white and orange growths found after several days on agar plates. Thank you so much in advance. Read More

Bonnie Bassler on the secret, social lives of bacteria

This recent talk at TED by Bonnie Bassler on bacterial communication (aka quorum sensing) was a viral hit among the science geeks on Twitter. It is a very educational and well thought out presentation that is great for personal viewing or showing in the classroom. It's a must watch! Read More

TWiV 283: No Reston for the weary

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

 Hosts: Vincent RacanielloAlan Dove Read More

Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate

Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown to have ... Read More

TWiV 125 Letters

Todd writes:


Hey Docs!


I'm a computer programmer who listens to podcasts on my long commute. The highest science education that I've had was college Chemistry. As an Electrical Engineer the science classes we took tended to not be biology oriented, so while so... Read More

Inside the Mind's Eye: Communicating Science in a New Media Era (MWV41)

Blogs, podcasts, and other new media outlets have changed the way people get their news. Immediate access to information presents new opportunities as well as challenges for science communication. Watch Carl Zimmer, science wr... Read More

TWiM 100 Letters

Matt Daugherty writes:


I just listened to the latest TWiM. Thanks for covering our horizontal gene transfer paper! It was great to hear you all talk about it and give your thoughts.


With regards to the selective pressure for retention of the Dae’s in genomes o... Read More

XMRV not detected in seminal plasma

How XMRV, the new human retrovirus associated with prostate cancer and chronic fatigue syndrome, might be transmitted among humans is unknown. The finding that the virus can be detected in prostate cancer cells, and in prostatic secretions of men with prostate cancer suggests that it could be se... Read More

TWiP 79 letters


Jesse writes:


Doctors TWiP,


I came across this paper and thought it sounded interesting for a discussion on TWiP:


Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Read More

TWiV 59

Nick writes:


I’m a bit behind in my Twiv listening, but I’d like to comment on something you said in Twiv 47. You have reminded us several times in the past that “viruses are not alive” and you embellished on this during Twiv 47 by saying that if they are not alive, they can’... Read More

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