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Google Flu Trends

Each week, millions of users around the world search for health information online. Google has found a close relationship between how many people search for flu-related topics and how many people actually have flu symptoms. Of course, not every person who searches for "flu" is actually sick, but... Read More

TWiM #49 transcript

Here is a transcript of TWiM episode #49, "Grape-like clusters". Thanks to Frank Shinneman for transcription.

The transcript is also available as a pdf file - click... Read More

TWiM 80 Letters

Bob writes:

Dear TWIM hosts,

I enjoyed episode 76, "Genetic biopixels and a pathogenic sweet tooth". I really enjoyed hearing about the course that Dr. Schaechter teaches and in particular the work his students did in developing the biosensor. I would like to ... Read More

Green Algae

The most clearly plant-like algae, this species gets its namesake hue from high levels of chlorophyll.

Their cell walls are made up of cellulose, the same material that makes up the cell walls in larger, multicellular plants. Like plants, they store the food they make through photosyn... Read More

Deep sequencing reveals viral vaccine contaminants

Use of the rotavirus vaccine Rotarix in the US has been temporarily suspended because the vaccine was found to be contaminated with porcine circovirus 1 DNA. The discovery was made in the laboratory of Dr. Eric Delwart, who has provided insight into what was found in Rotarix, and why he was anal... Read More

TWiV 289: Vinny and the capsids

Vinny and the capsids answer listener questions about the definition of life, state vaccination laws, the basic science funding problem, viral ecology, inactivation of viruses by pressure, and much more.

Hosts:  Read More

A Guide to Malaria

In observation of World Malaria Day this April 25, 2009 Scientific American has published a great online resource for people interested in malaria. "The international community has just two years to meet the United Nations's 2010 goal of providing protection and treatment to every person threate... Read More

TWiV 195 Letters

[we began be re-reading part of Deena's email from TWiV 193]

Ben writes:

Hello TWIV Crew,

I must first ap... Read More

MMP #12: Hydrogen from ground rocks can furnish microbial ecosystems with energy to drive growth.

Host: Jeff Fox with special guest, Jon Telling.

Jon Telling of Bristol University in Bristol, United Kingdom talks with Jeff Fox about his findings suggesting that the grinding of glaciers over rocks can liberate hydrogen, which, in turn, drives the growth of methanogens within microb... Read More

The Wall of Polio, version 3.0

Back in 2013 I built a Wall of Polio in my laboratory – a large stack of six-well cell culture plates that have been used to measure the concentration of polioviruses in various samples by plaque assay. It became a focal point of the lab at which many guests came to have their photographs taken.... Read More

TWiM #6 transcript

Here is a transcript of TWiM episode #6, "Antibacterial therapy with bacteriophage: Fact or fiction?". Thanks to Steve Stokowski for transcription.

The transcript is also available as a pdf file - click here to download Read More

TWiM 102 Letters

Dave writes:

TWIM Comrades--
I first want to compliment you on one of my most listened to podcasts, and one that I actually know what is being presented most of the time.

Now about the term Talmudic.
Do we need a name that is a legal commentary on th... Read More

Why do we still use Sabin poliovirus vaccine?

The Sabin infectious, attenuated poliovirus vaccines are known to cause vaccine-associated paralysis in a small number of recipients. In contrast, the Salk inactivated vaccine does not cause poliomyelitis. Why are the Sabin vaccines still used globally? The answer to this question requires a bri... Read More

Streptococcus pyogenes

Throat swab of (5) years old child from emergency department for culture and sensitivity clinical summary scarlet fever.

Streptococcus pyogenes, or Group A Streptococcus, is a spherical, Gram-positive bacterium.[1] S. pyogenes displays streptococcal group A antigen on its cell wall and typic... Read More

Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?

This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More

TWiV special: MERS-coronavirus in dromedary camels

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Host: Vincent Racaniello

Guests: Read More

A retrovirus makes chicken eggshells blue

When you purchase chicken eggs at the market, they usually have white or brown shells. But some breeds of chicken produce blue or green eggs. The blue color is caused by insertion of a retrovirus into the chicken genome, which activates a gene involved in the production of blue eggs. Read More

TWiV 118: The virus always rings twice

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Read More

TWiP 84 letters


Jesse writes:

Doctors TWiP,

I liked the discussion of the interaction of bacteria and Leishmania in sandfly guts; it was very interesting! Here is another suggestion if you need a topic to discuss:

Delivery of a functional anti-trypanoso... Read More

Sanctuary chimps show high rates of drug-resistant staph

Chimpanzees from African sanctuaries carry drug-resistant, human-associated strains of the bacteria Staphlyococcus aureus, a pathogen that the infected chimpanzees could spread to endangered wild ape populations if they were reintroduced to their natural habitat, a new study shows.

The study ... Read More
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