The TWiV gang answers follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus.
Vincent meets up with Janet Butel and Rick Lloyd at Baylor College of Medicine to talk about their work on polyomaviruses and virus induced stress.
Host: Vincent Racaniello
Guests... Read More
Is there such a thing as an obligatorily multicellular prokaryote? Merry Youle of the Small Things Considered blog reviews a recent paper published in the May issue of Applied and Environmental Microbiology that announces the finding of a new subgroup within magnetotactic multicellular prokaryot... Read More
Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More
Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).
Thick blood smears is de rigueur.
The Royal Society, founded in London in 1660 and one of the world's oldest scientific institutions, is marking the start of its 350th year by putting 60 of its most memorable research papers online. Several of these documents include papers by Sir Isaac Newton, Benjamin Franklin, and even Antoni... Read More
The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.
Tomorrow is the start of my new virology course at Columbia University. The course, Biology W3310, is aimed at advanced undergraduates and will be taught at the Morningside Campus of Columbia University. Read More
The Twivsters discuss how reverse transcriptase encoded in the human genome might produce DNA copies of RNA viruses in infected cells.
All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retro... Read More
Seth Berkley explains how smart advances in vaccine design, production and distribution are bringing us closer than ever to eliminating a host of global threats -- from AIDS to malaria to flu pandemics. Read More
The National Science Foundation has just launched Science360 Radio, a website and app for smart phones and iDevices, that streams science-focused audio content. (Disclaimer: All of MicrobeWorld's podcasts are included.) There are over 100 shows featured and the app is free.
While this much co... Read More
Last week I was at Cold Spring Harbor Laboratory to attend a ceremony designating the well-known laboratory on Long Island as a Milestone in Microbiology site. The purpose of this program, which is administered by the American Society for Microbiology, is to recognize institutions that have subs... Read More
The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn... Read More
Dear Vincent, Dickson and Daniel,
I like your idea of a TWIP coffee mug prize (or maybe a mug discount).
In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More
For my Microbiology course at the University of Puget Sound, I decided to ask my new crop of "micronauts" what the word "microbiology" meant to them on the first day of class. Here are their answers. My wife Jennifer Quinn and I put this together using art from former students. Hopefully, thi... Read More
As noted entomologist E.O. Wilson accepts his 2007 TED Prize, he makes a plea on behalf of his constituents, the insects and small creatures, to learn more about our biosphere. Wilson states that as we're still discovering tiny organisms indispensable to life we're steadily, methodically, and vi... Read More
Here is a transcript of TWiM episode #6, "Antibacterial therapy with bacteriophage: Fact or fiction?". Thanks to Steve Stokowski for transcription.
The transcript is also available as a pdf file - click here to download Read More
Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.
Host: Read More
A new paper publish in PLoS One concludes that programs that optimize adherence to highly-active antiretroviral therapy (HAART) through direct observation in pregnancy have the potential to diminish mother-to-child HIV transmission in a highly cost-effective manner. Read More