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Drivers of bacterial à-diversity depend on spatial scale

PDF of recent "Open Access" PNAS paper on bacterial biogeography. The paper (of which I am an author) made use of rRNA PCR to survey bacteria in salt marshes. The bacteria were surveyed broadly (using broadly targeted PCR primers) and narrowly (using primers that focused on specific taxonomic... Read More

TWiM #87: Avogadro, archaeal fossils, and ICAAC

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

Deans write to Obama about CIA vaccine scheme in Pakistan

Deans of public health schools in the United States have sent a letter to President Obama, in which they criticize the use of a vaccination campaign by the Central Intelligence Agency in Pakistan to hunt for Osama bin Laden. I wonder if he will reply. Read More

TWiV 60

Eric asked for “advice on how to bridge the gap between clinical medicine, public health, and virology research.” I asked Scott Hammer MD for his thoughts on this question. Here is Dr. Hammer’s response:


Hi Vincent:


Thanks for forwarding this comment. In response, I’d inform y... Read More

BacterioFiles 180 - Phage Functions Fight Fortifications

This episode: Some phages can fight back against bacterial defenses with recently discovered genes!


(8.3 MB, 9 minutes)


Show notes: 
Journal Paper Read More

El podcast del microbio Nº250. Cómo hacer un virus letal en cinco pasos (How to make a lethal virus in five steps)



























"El podcast del microbio" Nº 250 summarize the article published in November by New Scientist about the controversial work on mu... Read More

Precious Metals

Moselio Schaechter of the Small Things Considered blog reviews the results of a recent paper "Microbial metalloproteomes are largely uncharacterized" from the Department of Biochemistry and Molecular Biology at the University of Georgia, Athens, and ponders its implications.

Snippet:

"Now... Read More

Poliovirus on Time

Poliovirus has made the cover of Time magazine. The Time cover image for the 14 January 2013 issue is a model of poliovirus bound to a soluble form of its cellular receptor, CD155. I was part of the team that solved the structure of this complex in 2000, together with the laboratories of Jim Hog... Read More

WHO will switch to type 2 inactivated poliovirus vaccine

The World Health Organization’s campaign to eradicate poliomyelitis made impressive inroads in 2012: only 212 cases were reported, compared with 620 the previous year; moreover, India remained polio-free. The dark side of this story is that as wild polio is eliminated, vaccine-associated poliomy... Read More

Important Considerations for Determining qPCR Efficiency

One of the very first things you need to do when getting set up for quantitative PCR (qPCR) is to determine the efficiency of the assay because knowing the assay efficiency is critical to accurate data interpretation. And you have to do this every time you design and purchase a new primer pair.
... Read More

Viruses on Time

Poliovirus recently made the cover of Time magazine. Prompted by a reader question, I searched the Time archive to find out if there have been other virology-themed covers. I found fifteen in all, depicting poliovirus (3), herpesvirus (1), HIV/AIDS (4), influenza (5), and SARS coronavirus (2) (I... Read More

Green Algae

The most clearly plant-like algae, this species gets its namesake hue from high levels of chlorophyll.


Their cell walls are made up of cellulose, the same material that makes up the cell walls in larger, multicellular plants. Like plants, they store the food they make through photosyn... Read More

Antibiotics work against viruses

Got your attention, eh? This page discusses why so many people believe that antibiotics kill viruses, and what you can do about that myth. Actually, it's not even a myth ... antibiotics DO work against viruses. The problem is that the word "antibiotics" is redefined by some to be a synonym of... Read More

How to give a great lecture

There are many elements that go into making a great lecture, but the most important one is to lose the notes. If you are giving lectures in a course at any level, the worst practice you can engage in is to rely on notes. This behavior is problematic for several reasons. You will not properly kno... Read More

Influenza Information (H1N1)

A one-page primer on the H1N1 flu and what you can do to protect yourself and your family. Read More

Men More Likely to Commit Research Misconduct than Female Counterparts #mBio #science

It’s not hard to see that men are more likely to engage in risky behaviors than women, or that crime rates are many times higher among men, but this tendency to break the rules also extends to male scientists, according to a study to be published on January 22 in mBio®, the online open-access jo... Read More

El podcast del Microbio Nº149. Physical Virology (Virología Física)



























El Podcast del Microbio" Nº 149 is based in the Nature Physics article by W Roos y G.J.L Wuite. El Podcast del Microbio Nº ... Read More

Evidence-based antibiotic usage

New recommendation encourages physicians to prescribe _antibacterials_ instead of antibiotics for bacterial infections. This recommendation is based on compelling evidence that the word "antibiotic" confuses almost everyone, including some doctors. The confusion leads to strong patient demands... Read More

A WORD on the constraints of influenza virus evolution

Evolution proceeds by selection of mutants that arise by error-prone duplication of nucleic acid genomes. It is believed that mutations that are selected in a gene are dependent on those that have preceded them, an effect known as epistasis. Analysis of a sequence of changes in the influenza vir... Read More

All You Want to Know About Fungal Pathogens & Protozoan Parasites - at Keystone Symposia in Santa Fe, January 2012

Save the date for Keystone Symposia's meeting on "Fungal Pathogens: From Basic Biology to Drug Discovery" to be held January 15-20, 2012 at the Santa Fe Community Convention Center in Santa Fe, New Mexico. Organized by Joseph Heitman of Duke University, John Taylor of UC Berkeley and Leah E. Cow... Read More

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