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Green Algae

The most clearly plant-like algae, this species gets its namesake hue from high levels of chlorophyll.


Their cell walls are made up of cellulose, the same material that makes up the cell walls in larger, multicellular plants. Like plants, they store the food they make through photosyn... Read More

Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?

This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More

Spread of koala retrovirus in Australia

The Koala retrovirus (KoRV) continues to spread within Australia, according to results of a new analysis of a larger sample size from a wider geographical range than was previously studied. Read More

TWiV 222: Jumpin' Jack Flash, it's a GAS GAS GAS

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Hosts: Vincent Racaniello, Rich Condit Read More

TWiP 110: Malaria at the Bronx Zoo

The TWiP trio visit the Bronx Zoo where Paul solves the case of the Four Year Old with Pulmonary Edema, and talks about his career as the Chief Veterinarian and Director of the Zoological Health program for the Wildlife Conservation Society.


Hosts:  Read More

Evolution of a DNA Sequence Over Time

One of the basic requirements of evolution is variation in a population upon which selection can act. One of the sources of variation is mutation in DNA. These changes may or may not be reflected in the ensuing amino acid sequence of a protein. This exercise explores the additive effects of m... Read More

BacterioFiles 258 - Transformed Toxin Translocates Treatments

This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons!


(11.1 MB, 12.1 minutes)


Show notes: 
Journal Paper:

Chen C, Przedpelski A, Tepp WH, Pellett S, Johnson EA, Barbieri JT. 2015.... Read More

PolygenicBlog: Bugs and genes

This is a blog that tries to address the relationships between genes and environmental risk factors , particularly viruses, bacteria and parasites, in some common diseases, including Alzheimer's disease, Bipolar disorder, multiple sclerosis, Schizophrenia and Parkinson's disease and also provide... Read More

TWiV 311: Bulldogs go viral

Vincent visits the University of Georgia where he speaks with Zhen Fu and Biao He about their work on rabies virus and paramyxoviruses.


 


Host: Vincent Racaniello. Guests:  Read More

MMP #10: Examining the gut microbiota of American Indians of Cheyenne and Arapaho ancestry.

Host: Jeff Fox with special guests, Cecil M. Lewis, Jr. and Krithivasan Sankaranarayanan.


Lewis and Krithivasan Sankaranarayanan—“Krithi”-- both fro... Read More

Renew your Knowledge of Microbiology

Enjoy this scientific spring scavenger hunt and find the answers to these 10 questions on the history of microbiology. The birth of microbiology revolved around many key discoveries beginning around the mid to late 1600’s. These discoveries were at the cutting edge of science at the time and th... Read More

Bacterial Cells Engineered to Blink in Synch

Fluorescence-tagged Escherichia coli cells can be made to "blink" in unison by means of a constructed network of genes and proteins that coordinates oscillations within the growing cell population, according to Jeff Hasty and colleagues from the University of California, San Diego (UCSD) in La J... Read More

TWiV 321: aTRIP and a pause

Paul Duprex joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.


Hosts: Vincent Racaniel... Read More

Sanctuary chimps show high rates of drug-resistant staph

Chimpanzees from African sanctuaries carry drug-resistant, human-associated strains of the bacteria Staphlyococcus aureus, a pathogen that the infected chimpanzees could spread to endangered wild ape populations if they were reintroduced to their natural habitat, a new study shows.

The study ... Read More

TWiM 100 Letters

Matt Daugherty writes:


I just listened to the latest TWiM. Thanks for covering our horizontal gene transfer paper! It was great to hear you all talk about it and give your thoughts.


With regards to the selective pressure for retention of the Dae’s in genomes o... Read More

When Your Partner is NOT a Scientist

A recent article published by The Scientist called Power Couples gave advice and examples for scientist couples who have successfully balanced their life at home and in the lab. It was interesting from the perspective of how two very busy and career motivated people work together to have it al... Read More

Compiling a list of reporters who cover #microbiology stories well; suggestions wanted

I am attempting to compile a list of reporters who do a good job covering microbiology related topics. I have compiled a partial list and am soliciting additional suggestions. Read More

Prion contamination in the emergency room

Here is a follow-up to last week’s article that described a case of variant Creutzfeldt-Jacob disease in a Texas resident caused by ingestion of BSE-contaminated beef 14 years ago.

A 59 year old male patient was admitted to the trauma unit in Lancaster, PA with a self-inflicted gunshot wound ... Read More

TWiV 312: She sells B cells

The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.


Hosts:  Read More

Thirty years in my laboratory at Columbia University

Thirty years ago this month I arrived in the Department of Microbiology at Columbia University’s College of Physicians and Surgeons (P&S) to start my own laboratory. Thirty is not only a multiple of ten (which we tend to celebrate), but also a long time to be at one place. It’s clearly time to r... Read More
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