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Seth Berkley: HIV and flu - the vaccine strategy

Seth Berkley explains how smart advances in vaccine design, production and distribution are bringing us closer than ever to eliminating a host of global threats -- from AIDS to malaria to flu pandemics. Read More

Everyone Rowing in the Same Direction

Is there such a thing as an obligatorily multicellular prokaryote? Merry Youle of the Small Things Considered blog reviews a recent paper published in the May issue of Applied and Environmental Microbiology that announces the finding of a new subgroup within magnetotactic multicellular prokaryot... Read More

TWiV 238: Lost in translation

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Rich Condit, and Read More

April 2011 Microbe Feature article--BioCyc: Microbial Genomes and Cellular Networks

BioCyc: Microbial Genomes and Cellular Networks

by Peter D. Karp, Ingrid M. Keseler, Tomer Altman, Ron Caspi, Carol A. Fulcher, Pallavi Subhraveti, Anamika Kothari, Markus
Krummenacker, Mario Latendresse, Tom Lee, Suzanne M. Paley, Alexander G. Shearer, and Miles Trupp

The BioCyc system h... Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

Getting the Most Out of PCR

Learn about PCR and qPCR from world experts on the subject in this 6-part series brought to you over the web. Topics include the history of PCR from Carl Wittwer, an inventor of the LightCycler, discussions on the optimization and chemistry for PCR, and applications including methylation PCR and... Read More

TWiM 87 Letters

Varun writes:

Greetings TWiM Profz,

As a perso... Read More

Eurobarometer on antimicrobial resistance highlights areas for action

On 9 April 2010, the European Commission published the results of a Eurobarometer on antimicrobial resistance (AMR) which demonstrate the need for further progress on the issue in the European Union (EU) [1]. The report highlights public attitudes towards the use of antibiotics which are of conc... Read More

My first "Mu-Tube" video promoting microbial literacy: What does "microbiology" mean to students?

For my Microbiology course at the University of Puget Sound, I decided to ask my new crop of "micronauts" what the word "microbiology" meant to them on the first day of class. Here are their answers. My wife Jennifer Quinn and I put this together using art from former students. Hopefully, thi... Read More

TWiM #49 transcript

Here is a transcript of TWiM episode #49, "Grape-like clusters". Thanks to Frank Shinneman for transcription.

The transcript is also available as a pdf file - click... Read More

The Ghost Map - Author Steven Johnson on the 1854 Cholera Outbreak in London

Author Steven Johnson discusses The Ghost Map, his book about a cholera outbreak in 1854 London and the impact it had on science, cities and modern society. Read More

TWiV 326: Giving HIV a flat tyr

Hosts: Vincent RacanielloAlan Dove, and  Read More

El podcast del Microbio Nº 204. Mosquitos, virus y algo de sexo

El podcast del Microbio Nº204 is based in the Virology Blog post: "The press concludes that arboviruses can be sexually tra... Read More

TWiP 80 letters

Jessica writes:

Hello Dr Racaniello and Despommier,

I recently saw an article about the paper linked below on Science Daily and thought it might be worth a discussion on TWIP. It is about the possibility of bed bugs being a vector for T. cruzi. I would love to... Read More

Claire Fraser-Liggett on “Complex microbial communities: We’re not in Kansas anymore”

Claire Fraser-Liggett, Director of the Institute for Genome Sciences and professor at the University of Maryland School of Medicine, gives the June 2, 2010 keynote at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM. Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.

Hosts: Vincent Racaniello Read More

TWiV 310: From bacteriophage to retroviruses with Ann Skalka

Vincent and Glenn meet up with Ann and talk about her long and productive career in virology, from biochemistry to bacteriophage lambda to retroviruses.

Hosts: Vincent Racaniello and Read More

Emerging disease: Looking for trouble

How do you persuade philanthropists to pay $1 million for every pathogenic human virus you discover? Anjali Nayar talks to 'virus hunter' Nathan Wolfe in Cameroon to find out.

Every day, more than 100 patients line up for treatment outside the bare cement walls of a rural health clinic in the... Read More

How Small Can You Get

parvovirus_B19 Read More


Archaeans are single-celled creatures that join bacteria to make up a category of life called the Prokaryotes (pro-carry-oats). Prokaryotes' genetic material, or DNA, is not enclosed in a central cellular compartment called the nucleus. Bacteria and archaea are the only prokaryotes. ... Read More

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