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Archaea of Note


  • Lobus fulgidus is a sulfur-reducer that can sour oil wells.

  • Halobacteria are salt-loving microbes that give a pink tinge to salt water evaporation ponds, the Dead Sea and salted fish.

  • Pyrolobus fumarii led scientists to extend the upper te... Read More

An Inactive Mine Provides Active Opportunities

Elio Schaechter of Small Things Considered describes the work by members of Jill Banfield’s lab at Berkeley on a unique set of mine-dwelling microorganisms dubbed ARMAN (for Archaeal Richmond Mine Acidophilic Nanoorganisms). These microbes illustrate many surprising characteristics such as "thei... Read More

El podcast del Microbio Nº 286. Mutaciones tempranas en el VIH (Early mutations in HIV)



























El podcast del Microbio Nº 286 summarize the article by Henn et al published in PLoS: Pathogens about the impact of early minor ... Read More

Promiscuous Bacteria and Viral Playboys

Bacteria have been sexually promiscuous, swapping genes with gusto, for a very long time. More than 15% of E. coli's genome has arrived via horizontal gene transfer (HGT), with some 200 installments having turned up since it diverged from Salmonella 100 million years ago. And, as you are probabl... Read More

A system‐level model for the microbial regulatory genome

Microbes can tailor transcriptional responses to diverse environmental challenges despite having streamlined genomes and a limited number of regulators. We present data‐driven models that capture the dynamic interplay of the environment and genome‐encoded regulatory programs of two types of prok... Read More

CDC's 2009 H1N1 Vaccination Recommendations (Podcast)

Dr. Tony Fiore discusses who should be vaccinated against 2009 H1N1 flu during the 2009-2010 season. He explains the target groups for vaccination, and how these groups differ from those recommended for seasonal flu vaccination. Read More

Curbing Domestic Violence Key to Reducing HIV Infection Among South African Women

Women in South Africa who are victims of domestic violence are more likely to become infected with HIV compared to women who do not experience such behavior, according to a study published June 16, 2010 in The Lancet'‘s Online First.

Nearly one in seven new HIV infections could be prevented i... Read More

TWiP 76 letters


Daniel writes:


Dear Vincent and Dickson,


I just returned from the annual meeting of the International Society of Travel Medicine (ISTM) where I enjoyed many fantastic lectures and caught more Cutthroat Trout fly fishing the upper Snake River during one ev... Read More

TWiM #49 transcript

Here is a transcript of TWiM episode #49, "Grape-like clusters". Thanks to Frank Shinneman for transcription.


The transcript is also available as a pdf file - click... Read More

TWiV 295: A nonslip grippe and Lassa's LAMP

The TWiVome discusses an miRNA based strategy to mitigate risk of gain of function studies, and identification of a second receptor required for Lassa virus entry.


Hosts: Vincent Racaniello,&n... Read More

Design and Testing of Protein Combinatorial Libraries

In this video Stephen L. Mayo, Bren Professor of Biology and Chemistry, California Institute of Technology, discusses the challenges of designing new proteins that fold into a particular structure or perform a particular function. One method is to computationally design a protein based solely up... Read More

TWiM #6 transcript

Here is a transcript of TWiM episode #6, "Antibacterial therapy with bacteriophage: Fact or fiction?". Thanks to Steve Stokowski for transcription.


The transcript is also available as a pdf file - click here to download Read More

Evidence-based antibiotic usage

New recommendation encourages physicians to prescribe _antibacterials_ instead of antibiotics for bacterial infections. This recommendation is based on compelling evidence that the word "antibiotic" confuses almost everyone, including some doctors. The confusion leads to strong patient demands... Read More

NIH head defends new center for translational science

Head of the US National Institutes of Health Francis Collins was asked some tough questions by a House of Representatives subcommittee examining the new National Center for Advancing Translational Sciences, NCATS. The goal of the new center, opened in 2012, is to reduce the amount of time needed... Read More

El podcast del Microbio Nº234. Mejor que el sexo (Better than sex)



























El podcast del microbio Nº 234 is about the ecological importance of Horizontal Gene Transfer between bacteria as described by S... Read More

Audio interview with Dylan Pillai of the University of Toronto

Jeff Fox of Microbe magazine interviews Dylan Pillai of the University of Toronto on how genomic analysis is used by epidemiologists and clinical microbiologists to reconstruct bacterial disease outbreaks or analyze difficult individual cases Read More

HIV gets the zinc finger

Because all animal viruses initiate infection by binding to a receptor on the cell surface, this step has long been considered a prime target for antiviral therapy. Unfortunately, drugs that block virus attachment to cells have never shown much promise. Another approach, which is to ablate the r... Read More

Collection of Microbial Discovery Activities for K-12

The American Society for Microbiology has posted a collection of Microbial Discovery Activities designed for K-12 teachers to facilitate the incorporation of microbiology within science courses. Activities come from the community at large. All submissions are reviewed by the ASM Committee on K-1... Read More

TWiP 65 letters

 


Perry writes:


Greetings Vincent and Dick,


Hooray for finally mentioning G. pulchrum in episode 62, my most favorite parasite and one worthy of further discussion. As a diagnostic veterinary pathologist, I encounter this spirurid in approximately... Read More

The most important paper ever in microbiology

Jonathan Eisen (@phylogenomics on Twitter) has a new post on his The Tree of Life blog that looks at why the paper "Phylogenetic structure of the prokaryotic domain: The primary kingdoms" by Carl Woese and George Fox may be the most important paper (see http://www.pnas.org/content/74/11/5088.ful... Read More

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