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Candida's Unstable Chromosomes & Unorthodox Sex

Dean Dawson, Associate Member of the Cell Cycle and Cancer Biology Research Program at the Oklahoma Medical Research Foundation, has authored a post on Small Things Considered which explores Candida's chromosomal instability and unorthodox reproduction process.

"Who hasn't heard of Candida? I... Read More

El podcast del Microbio Nº234. Mejor que el sexo (Better than sex)



























El podcast del microbio Nº 234 is about the ecological importance of Horizontal Gene Transfer between bacteria as described by S... Read More

El Podcast del Microbio" Nº 152 and 153. El experimento de Tuskegee (The Tuskegee Syphilis Experiment)



























El Podcast del Microbio" Nº 152 and 153 deals with the history of the infamous Tuskegee Syphilis Experiment and its follow-... Read More

TWiP 50 Letters

Alaric writes:


Hello Vince and Dick,


I just found your podcast and I love it! You have some wonderfully witty banter.


I am only on my 4th episode (that's what you call a podcast segment right?), and have a question pertaining to my original reason for ... Read More

A Global Metabolic Shift Is Linked to Salmonella Multicellular Development

Bacteria can elaborate complex patterns of development that are dictated by temporally ordered patterns of gene expression, typically under the control of a master regulatory pathway. For some processes, such as biofilm development, regulators that initiate the process have been identified but s... Read More

NIH head defends new center for translational science

Head of the US National Institutes of Health Francis Collins was asked some tough questions by a House of Representatives subcommittee examining the new National Center for Advancing Translational Sciences, NCATS. The goal of the new center, opened in 2012, is to reduce the amount of time needed... Read More

El podcast del microbio Nº185. ¿Qué hacemos con la viruela? (What do we do with smallpox?)



























El podcast del Microbio Nº185 deals with the discussions inside WHO about the fate of the last vials with smallpox virus. E... Read More

El Podcast del Microbio Nº 361. Resistencia a los antibióticos, un problema de narices. (Antibiotic resistance, just under your nose)



























El podcast del microbio Nº 361 summarize the article writen by Marks LR, Reddinger RM and Hakansson AP and published in mBio about the high levels of genetic recombination in Streptococcus pneumoniae ... Read More

TWiV 105 Letters

Timothy writes


Dear Vince and Alan,


Being a seasoned virologist and a science writer, I was hoping you could discuss the interface between basic science, public health, the media and the general public...


While I was listening to you d... Read More

Important Considerations for Determining qPCR Efficiency

One of the very first things you need to do when getting set up for quantitative PCR (qPCR) is to determine the efficiency of the assay because knowing the assay efficiency is critical to accurate data interpretation. And you have to do this every time you design and purchase a new primer pair.
... Read More

Curious about the Human Microbiome?

The American Academy of Microbiology has released its newest report on the human microbiome. Based on the deliberations of some of the leading experts, the report answers common questions people have about this new field of science. While there is still much to be learned, this report presents t... Read More

BacterioFiles 172 - Sunlight-Snackers Seize Sparks

This episode: Some photosynthetic bacteria can use electricity for their metabolism to make useful stuff too!


(9.2 MB, 10 minutes)


Show notes: 
News item 1... Read More

Should variola virus, the agent of smallpox, be destroyed?

Later this month (May 2014) the World Health Assembly will decide whether to destroy the remaining stocks of variola virus – the agent of smallpox – or to allow continued research on the virus at WHO-approved laboratories. We are interested in your opinion on this issue. Please follow the link t... Read More

Drivers of bacterial à-diversity depend on spatial scale

PDF of recent "Open Access" PNAS paper on bacterial biogeography. The paper (of which I am an author) made use of rRNA PCR to survey bacteria in salt marshes. The bacteria were surveyed broadly (using broadly targeted PCR primers) and narrowly (using primers that focused on specific taxonomic... Read More

Precious Metals

Moselio Schaechter of the Small Things Considered blog reviews the results of a recent paper "Microbial metalloproteomes are largely uncharacterized" from the Department of Biochemistry and Molecular Biology at the University of Georgia, Athens, and ponders its implications.

Snippet:

"Now... Read More

A virology course for all

The spring semester has begun at Columbia University, which means that it is time to teach my virology course. The fourth annual installment of my virology course, Biology W3310, has begun. This course, which I taught for the first time in 2009, is intended for advanced undergraduates and conven... Read More

Archaea of Note


  • Lobus fulgidus is a sulfur-reducer that can sour oil wells.

  • Halobacteria are salt-loving microbes that give a pink tinge to salt water evaporation ponds, the Dead Sea and salted fish.

  • Pyrolobus fumarii led scientists to extend the upper te... Read More

El podcast del microbio Nº 255: Hongos contra el picudo rojo (Fungi against the red palm weevil )



























El podcast del Microbio Nº255 explains the use of the fungus Beauveria bassiana as bioinsecticide for the control of the red pa... Read More

India has been free of polio for three years

Three years ago today, on 13 January 2011, the last case of poliomyelitis was reported in India. This achievement represents a remarkable turnaround for a country where control of the disease had for years been extremely difficult. As recently as 2009 there were 741 confirmed cases of polio caus... Read More

TWiV 238: Lost in translation



Hosts: Vincent Racaniello, Rich Condit, and Read More

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