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TWiV 48

Rodney writes:


Hello, I have been an avid listener of TWiV over the last 9 months or so and have very much enjoyed the podcast. It is always great to hear a broad, informed discussion on virology, and your recent podcast on viral classification was of particular interest to m... Read More

TWiP 60 letters

Maureen writes:


Our vaccine unit here at NIH did a study of malaria vaccine with some promising results. I know Dickson has been a champion of conquering malaria.


http://www.scie... Read More

El podcast del Microbio Nº 286. Mutaciones tempranas en el VIH (Early mutations in HIV)



























El podcast del Microbio Nº 286 summarize the article by Henn et al published in PLoS: Pathogens about the impact of early minor ... Read More

Robert A. Weisberg, 1937-2011

Robert A. Weisberg was a Scientist Emeritus at NCI until the time of his death on 1 September 2011. Previously he was Chief of Microbial Genetics at NICHHD, a position he retired from in 2008. He was a pioneer in the study of the bacteriophage lambda. His research lead to seminal contributions a... Read More

Lab Tests Online - a resource site for patients, caregivers and medical professionals

Lab Tests Online has been designed to help you, as a patient or family caregiver, to better understand the many clinical lab tests that are part of routine care as well as diagnosis and treatment of a broad range of conditions and diseases. If you are a medical professional, this site can serve ... Read More

XMRV, Chronic Fatigue and prostate cancer

The XMRV retrovirus has been implicated in chronic fatigue syndrome and prostate cancer. A homology search comparing retroviral with human proteins revealed short contiguous amino acid strings (typically 5-8 aa) matching human proteins whose dysfunction might be expected to cause fatigue, includ... Read More

TWiP 3 letters

Björn writes: (first letter to TWiP)


Hi Dick and Vincent,



My name is Björn. I am a biochemist and PhD student working on trypanosomes here in Germany. I am a long time listener of your twiv podcast and just listened to the first  Read More

Biotech Revolution (BBC Four)

Theoretical physicist and futurist Michio Kaku looks at the revolution in genetics and biotechnology, which promises unprecedented health and longevity but also raises fears of a future where we can genetically engineer people. The documwentary asks will we, as transhumanists expect, evolve into... Read More

A single amino acid change switches avian influenza H5N1 and H7N9 viruses to human receptors

Two back-to-back papers were published last week that provide a detailed analysis of what it would take for avian influenza H5N1 and H7N9 viruses to switch to human receptors. A single amino acid change in the viral hemagglutinin protein is sufficient to quantitatively change binding of the viru... Read More

TWiM #46 transcript

Here is a transcript of TWiM episode #46, "Spore!". Thanks to Frank Shinneman for transcription.


The transcript is also available as a pdf file - click here to download.


Read More

Pandemics in Retrospective

Now that we have experienced several months of the H1N1 pandemic, what have we learned about how it was handled? Watch Dr. Nicole Lurie (U.S. Department of Health and Human Services) and Dr. Kathryn Edwards (Vanderbilt University), discuss the public health responses to H1N1. Participants compar... Read More

Report to the President on U.S. Preparations for 2009-H1N1 Influenza

Click "source" to view the full "Report to the President on U.S. Preparations for 2009-H1N1 Influenza" from the President’s Council of Advisors on Science and Technology.

Here is the Council's "planning scenario":

Indeed, the 2009-H1N1 influenza is already responsible for significant morbi... Read More

ASM 2010 Posters: The results of fruitful collaborations with scientists all over the world

Most of you are probably back to work after the ASM conference in San Diego. It was a great conference with a lot of exciting talks and posters and we hope you enjoyed our beautiful city.

MO BIO Labs presented four posters at ASM and the PDFs are now available online for viewing. These were t... Read More

Avian influenza H7N9 viruses isolated from humans: What do the gene sequences mean?

There have been over 60 human infections with avian influenza virus H7N9 in China, and cases have been detected outside of Shanghai, including Beijing, Zhejiang, Henan, and Anhui Provinces. Information on the first three cases has now been published, allowing a more detailed consideration of the... Read More

Collection of Microbial Discovery Activities for K-12

The American Society for Microbiology has posted a collection of Microbial Discovery Activities designed for K-12 teachers to facilitate the incorporation of microbiology within science courses. Activities come from the community at large. All submissions are reviewed by the ASM Committee on K-1... Read More

Human virus transfers oncogenic molecules horizontally

This is a paper that speaks of horizontal gene transfer in cancer, something that is against the widely recognized model of cancer development of a vertically evolved system that gives rise to tumors. Albeit, this system involves an in vitro model of a EBV induced cancer, viruses have historica... Read More

Bacteria Living Without Phages?

Are there environments where there are abundant bacteria and no phages? Sounds like one of our Talmudic Questions, but this one has a specific answer, and that answer is Yes. That environment was found within a cystic fibrosis (CF) lung.

This story comes from a pair of papers recently publish... Read More

Audio interview with Tina Valbh of Pharmaka Consulting on new hepatitis C drugs

Jeff Fox of Microbe Magazine discusses new hepatitis C drugs with Tina Valbh of Pharmaka Consulting Read More

BacterioFiles 172 - Sunlight-Snackers Seize Sparks

This episode: Some photosynthetic bacteria can use electricity for their metabolism to make useful stuff too!


(9.2 MB, 10 minutes)


Show notes: 
News item 1... Read More

Candida's Unstable Chromosomes & Unorthodox Sex

Dean Dawson, Associate Member of the Cell Cycle and Cancer Biology Research Program at the Oklahoma Medical Research Foundation, has authored a post on Small Things Considered which explores Candida's chromosomal instability and unorthodox reproduction process.

"Who hasn't heard of Candida? I... Read More

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