I really enjoyed your podcast about reverse transcription. I was wondering what makes retroviruses like HIV impossible for our bodies fight off. Are there any retroviruses that can be eliminated from the body?
I was browsing on the "Chronic ... Read More
Host: Vincent Racaniello
Guests: Ben Fensterheim, Megan Freeman, Bobak Parang, and Meredith Rogers
Vincent... Read More
This episode: Clostridium bacteria that infect potatoes can both kill competitors and tolerate oxygen, thanks to the pink compounds they produce!
(12.4 MB, 13.5 minutes)
Viruses are found on or in just about every material and environment on Earth from soil to water to air. They're basically found anywhere there are cells to infect. Viruses have evolved to infect every form of life, from animal to plant and from fungi to bacter... Read More
This episode: Discovery of a bacterium infected by two distinct organisms at the same time!
The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.
The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.
The TWiVome discusses an miRNA based strategy to mitigate risk of gain of function studies, and identification of a second receptor required for Lassa virus entry.
Have you heard about the Earth Microbiome Project? Led by the laboratories of Jack Gilbert from Argonne National Labs along with Folker Meyer (Argonne), Janet Jansson (LBNL), Rob Knight (University of Colorado), this is a pioneering effort to characterize the global microbial taxonomic and func... Read More
Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).
Thick blood smears is de rigueur.
Dotplots are an extremely useful way of visualizing comparisons of small and large DNA sequences (as well as protein sequences), providing insight into the degree of similarity, deletions, insertions and direct and indirect repeats. In a dotplot, each nucleotide, or small window of nucleotides, ... Read More
This episode: Bacteria in hydrothermal vents that feed their host tubeworms evacuate when their hosts perish!
(9 MB, 9.8 minutes)
When I am asked to name the most lethal human virus, I never hesitate to name rabies virus. Infection with this virus is almost invariably fatal; just three unvaccinated individuals have been known to survive. New evidence from humans in the Peruvian Amazon suggests that the virus might be less ... Read More
Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.
Host: Read More
This episode: A bacteria-virus system for developing useful enzymes!