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Why do we still use Sabin poliovirus vaccine?

The Sabin infectious, attenuated poliovirus vaccines are known to cause vaccine-associated paralysis in a small number of recipients. In contrast, the Salk inactivated vaccine does not cause poliomyelitis. Why are the Sabin vaccines still used globally? The answer to this question requires a bri... Read More

Microbial Warfare in the Underworld: Searching for New Antibiotics

This month we talked with Dr. Christine Salomon, Assistant Professor at the Center for Drug Design in the University of Minnesota. Dr. Salomon’s work intersects chemistry and microbial ecology in the hunt for interesting new natural products with far reaching potential applications. While much... Read More

TWiM 64 Letters

Tim writes:

Vincent and friends,

While driving around a field cutting hay lost in my science podcast playlist the episode of TWIM #61 came up and I had to listen intently as salmonella typhimurium came up as this is a common enteric issue in agriculture. When ... Read More

El podcast del Microbio Nº 210, 211 and 212: Microbioma y Metagenómica

El podcast del Microbio Nº210, 211 and 212 is dedicated to the recent discovery that there are three kinds of intestinal m... Read More

An Introduction to Viruses - Kahn Academy

An introduction to viruses created by Salman Khan of The Khan Academy, a one person, not-for-profit organization with the mission of providing a high quality education to anyone, anywhere.

While the Kahn Academy has over 25 videos devoted to topics in biology, there are hundreds more in a va... Read More

XMRV not detected in seminal plasma

How XMRV, the new human retrovirus associated with prostate cancer and chronic fatigue syndrome, might be transmitted among humans is unknown. The finding that the virus can be detected in prostate cancer cells, and in prostatic secretions of men with prostate cancer suggests that it could be se... Read More

Cheap Exports: The Economics of Protein Production

Daniel Smith, a graduate student in the Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, has a post on the Small Things Considered blog related to his recent paper, Economical Evolution: Microbes Reduce the Synthetic Cost of Extracellular Proteins, ... Read More

HIV cure could be all in the 'mix'

Current HIV treatments do not eradicate HIV from host cells but rather inhibit virus replication and delay the onset of AIDS. However, a new research published in BioMed Central's open access journal, AIDS Research & Therapy describes an innovative approach to eliminate HIV in host by targeted ... Read More

UCLA Pioneering Microbiology Educator and Author Discusses Innovative Teaching Methods

In this monthly interview series, meet Erin Sanders-Lorenz, an Adjunct Assistant Professor in the Department of Microbiology, Immunology, & Molecular Genetics at UCLA , co-author of the new book, "I, Microbiologist: A Discovery-based Course in Microbial Ecology and Molecular Evolution" and a lea... Read More

TWiP 95 letters

Ruben writes:

Dear Day-Twippers,

I am a big fan of TWIP. You do so many things right, that a little problem in your TWiP94 broadcast is not a big deal. As you may already know all three drugs in the Nutman et al. study are small molecules, not monoclonals, the... Read More

Polio immunizers murdered by Taliban

Maryn McKenna summarizes what we know about the murder of six people working as polio vaccinators who were targeted in three separate coordinated attacks in Pakistan. This comes in the wake of the CIA ruse in 2011 who used an immunization campaign to find Osama Bin Laden. Read More

Honoring the Memory of Another

The late Edward Leadbetter had a huge impact on my life as an academic, and a microbiologist. In this post, I try to give some appreciation to what he meant to me. Read More

TWiV 125 Letters

Todd writes:

Hey Docs!

I'm a computer programmer who listens to podcasts on my long commute. The highest science education that I've had was college Chemistry. As an Electrical Engineer the science classes we took tended to not be biology oriented, so while so... Read More

Could a plant virus have found a way to infect humans?

It has always been assumed that plant viruses cannot infect animals, and vice versa, but plant viruses are known to be abundant in human faeces.

Now Didier Raoult at the University of the Mediterranean in Marseille, France, and his team think a pepper virus is making people sick, too.

They... Read More

TWiV 307: Ebola aetiology

Tara Smith joins the TWiEBOVsters to discuss the Ebola virus outbreak in west Africa, spread of the disease to and within the US, transmission of the virus, and much more.

Hosts: Vincent Racaniello Read More

TWiV 292: Medimmune goes viral

Vincent visits Medimmune and speaks with Wade, Matt, Nicole, and Ken about why they work in industry and their daily roles in a biotechnology company.

Hosts: Vincent Racaniello

Guests: Wa... Read More

Freshman Symbiosis Course and Jack Gilbert!

As my Fall semester approaches, I am reflecting on last Fall. I taught a freshman seminar course revolving around symbioses and parasitism, and was fortunate to have many well known scientists be willing to "virtually visit" my class! Here is my report from last year on the great Jack Gilbert.... Read More

TWiP 64 letters

Richard writes:

Good morning, day, evening (depending on your time of day). Esteemed professors!

Firstly my weather report, for Weston super Mare, uk.

It is currently 3 centigrade (feels like 2C), dew point 4C, humidity 78%, there has been 1m... Read More

TWiV 243: Live from ASV at Penn State

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Rich Condit, and Read More

TWiP 81 letters

Allan writes:

Dear Vincent & Dickson… and Daniel,

I always enjoy listening to TWIP here in Kona, Hawaii.

Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
(FREEZING, as few of us hav... Read More

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