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Interview of Dr. Tim Sandle

Q) Dr. Tim Sandle, the well known researcher, professor, author and science communicator. It is much interesting for me to take an interview of an eminent person who is well known for the communicating science. Starting from your early childhood life, how you used to take science as that time?
... Read More

Do We Need a Climate Solution for Indoors?

We typically spend close to 90 percent of our time inside - at school, work and home. While outdoor air quality is very important, so too is the quality of the air we breathe at home and the office. Yet most of us know very little about the condition of our indoor climate.  The chemicals ... Read More

Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate

Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown to have ... Read More

Single-minded Mission

Viruses exist for one purpose only: to reproduce. To do that, they have to take over the reproductive machinery of suitable host cells.


Upon landing on an appropriate host cell, a virus gets its genetic material inside the cell either by tricking the host cell to pull it inside, like ... Read More

BacterioFiles 193 - Milk Modifies Monkey Microbes

This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!


(7.7 MB, 8.4 minutes)


Show notes: 
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TWiP 90: A carbuncle is a large furuncle

Vincent, Dickson, and Daniel discuss identification of an erythrocyte protein essential for invasion of Plasmodium falciparum, and introduce a new case study.


Hosts:  Read More

BacterioFiles 204 - Animalcules Assist Agave Amino Accumulation

This episode: Bacteria living in plants seem to be contributing to plants' nutrition, possibly reducing the need for fertilizer!


(17.5 MB, 19.15 minutes)


Show notes: 
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HIV cure could be all in the 'mix'

Current HIV treatments do not eradicate HIV from host cells but rather inhibit virus replication and delay the onset of AIDS. However, a new research published in BioMed Central's open access journal, AIDS Research & Therapy describes an innovative approach to eliminate HIV in host by targeted ... Read More

Polio immunizers murdered by Taliban

Maryn McKenna summarizes what we know about the murder of six people working as polio vaccinators who were targeted in three separate coordinated attacks in Pakistan. This comes in the wake of the CIA ruse in 2011 who used an immunization campaign to find Osama Bin Laden. Read More

New Diagnostic Fast and Effective at Finding TB in Elephants: Benefits for Pachyderms and Public Health

A serological test is highly accurate at finding tuberculosis infection in elephants, and can determine such infection years before culture, according to a study in the August Clinical and Vaccine Immunology (click source to download the .pdf of the journal article). The issue is critical not on... Read More

TWiP 71 letters


Heather writes:


Hi Dr.s R&D,


I thought you might be interested in this news article about aquaculture in Hong Kong. Perhaps it's time for another fish parasite episode? I love the podcast, keep up the great work.


Heather


Bill writes: Read More

TWiV 235: Live in Edmonton, eh?

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Hosts: Vincent Racaniello and Rich Condit Read More

TWiM #105: Real bugs with legs

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiV 301: Marine viruses and insect defense

At the International Congress of Virology in Montreal, Vincent speaks with Carla and Curtis about their work on RNA interference and antiviral defense in fruit flies, and viruses in the sea, the greatest biodiversity on Earth.


Host:  Read More

TWiV 233: We're surrounded

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Hosts: Vincent Racaniello, Rich Condit, Read More

Universal influenza vaccines

The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn... Read More

BacterioFiles Micro Edition 31 - Bacterial Biofertilizer

This episode: Bacteria as fertilizer!


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Inhibition of XMRV by a weapon of mass deamination

All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retro... Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More
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