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TWiP 56 letters

Suzanne writes:


Your discussion about technology and fixing things here before we go out into space made me wonder if space exploration might turn out to be like investigative science. In the process of exploring space we might run across the means of fixing our probl... Read More

TWiV 362: Gotta catch 'em all

Hosts: Vincent RacanielloDickson DespommierAlan Dove, Read More

TWiP 100: Driving past a milestone

The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modification of malaria mosquitoes using a Cas9-mediated driver gene.


Hosts:  Read More

TWiV 75: Rabies rampant

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On episode #75 of the podcast This Week in Virology, Vincent, Alan, and Matt review contamination of Rotarix with circovirus DNA, antigenic similarity between 1918 and 2009 H1N1 influenza, a ... Read More

BacterioFiles Micro Edition 32 - Virus Versus Malignancy Matrix

This episode: Virus + bacterial enzyme = cancer killer!


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10 Ways to Be Your OWN Boss In The Lab

In an ideal world, every PI would be a nurturing and challenging mentor who carefully guides your project and is invested in developing your skills as a scientist. In the real world, however, that kind of leadership can be hard to find.

In any case, one of the most important and useful mental... Read More

Bornavirus DNA in the mammalian genome

The chromosomal DNA of several mammals has been found to contain sequences related to the nucleoprotein (N) gene of bornaviruses, enveloped viruses with a negative-strand RNA genome. I am amazed by this finding. How did bornaviral DNA get in our chromosomes, and what is it doing there? Read More

TWiV 236: Flu gets the VIP treatment

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Hosts: Vincent Racaniello, Alan Dove, and Read More

TWiM 57 Letters

Wink writes:


Great HAI work! I'm not through it yet. I want to question, though, whether fomites are really important in influenza transmission. I don't think so.
Wink Weinberg (ID)


[flu can transmit by fomites in guinea pigs: Read More

TWiV 269: Herpesvirus stops a nuclear attack

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Hosts: Vincent Racaniello, Dickson Despommier Read More

El Podcast del Microbio: Amor de Madre





























In this audio in spanish language from "El podcast del microbio" I made a resume of the post "Mother's Love" published in Moselio Schaecht... Read More

Multiple Displacement Technology Goes Digital: a method for enumeration of bacterial nucleic acid contamination in enzymes

Is bacterial DNA contamination in your whole genome amplification kit a problem? For microbiologists it sure is. WGA is a technique where the complete genomic content of a sample is amplified non-specifically and at a single temperature (isothermically). The presence of any contaminating DNA in ... Read More

TWiP 52 Letters

Jason writes:


Hi Drs. Despommier and Racaniello,


This week you wondered why the immune-activating receptor for Toxoplasma gondii, TLR11, is present in mice but not in humans. You noted that it looks like there's no selective pressure keeping it around in us an... Read More

TWiV 276: Ramblers go viral

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 Host: Vincent Racaniello


Guests: Read More

Can You Protect Your Tummy From Traveler's Diarrhea?

It goes by many names: Delhi belly. Montezuma's revenge. The Aztec two-step. But doctors use one not-so-glamorous term: traveler's diarrhea. Read More

Everyday Roles

Some people think it would be great if scientists could wipe out all the microbial bugs! Should we do it, and why or why not?


We get a lot of requests to track down the nasty bugs that are making people sick. It's true that some microbes cause health problems such as strep throat, chi... Read More

TWiP 81 letters


Allan writes:


Dear Vincent & Dickson… and Daniel,


I always enjoy listening to TWIP here in Kona, Hawaii.


Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
(FREEZING, as few of us hav... Read More

TWiV 79 letters

Ben writes:


I really enjoyed your podcast about reverse transcription.  I was wondering what makes retroviruses like HIV impossible for our bodies fight off.  Are there any retroviruses that can be eliminated from the body?


Paula writes:


I was browsing on the "Chronic ... Read More

The Limitations of the Luria-Bertani Medium

Hiroshi Nakaido, PBD Faculty Scientist, Structural Biology Department, and Professor of Biochemistry and Molecular Biology, UC Berkeley, has authored a guest post on the Small Things Considered Blog regarding the limitations of LB medium.

"LB broth contains, per ml, 10 mg tryptone (... Read More

TWiP 53 Letters

John writes:


Dear Vincent and Dickson,


I just heard your most recent TWIP. Please keep these podcasts going! I love listening to your podcasts and hearing your enthusiasm for my favorite biological topic, parasites. Remember that for every fan... Read More

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