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BacterioFiles Micro Edition 27 - Ingenious Influenza Immunizations

This episode: Flu vaccine made by bacteria!


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Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate

Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown to have ... Read More

Thirty years in my laboratory at Columbia University

Thirty years ago this month I arrived in the Department of Microbiology at Columbia University’s College of Physicians and Surgeons (P&S) to start my own laboratory. Thirty is not only a multiple of ten (which we tend to celebrate), but also a long time to be at one place. It’s clearly time to r... Read More

TWiM 57 Letters

Wink writes:


Great HAI work! I'm not through it yet. I want to question, though, whether fomites are really important in influenza transmission. I don't think so.
Wink Weinberg (ID)


[flu can transmit by fomites in guinea pigs: Read More

BacterioFiles 184 - Fungus Friends Fabricate Fragrance

This episode: Truffle's microbiome helps produce its attractive aromas!


(12.5 MB, 13.6 minutes)


Show notes: 
Journal Paper


<... Read More

Universal influenza vaccines

The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn... Read More

An Introduction to Viruses - Kahn Academy

An introduction to viruses created by Salman Khan of The Khan Academy, a one person, not-for-profit organization with the mission of providing a high quality education to anyone, anywhere.

While the Kahn Academy has over 25 videos devoted to topics in biology, there are hundreds more in a va... Read More

El podcast del Microbio Nº 210, 211 and 212: Microbioma y Metagenómica



























El podcast del Microbio Nº210, 211 and 212 is dedicated to the recent discovery that there are three kinds of intestinal m... Read More

BacterioFiles 175 - Bacteria Build Better Biofilms

This episode: Engineered bacteria can be made to produce many different useful kinds of biofilm!


(10.5 MB, 11.5 minutes)


Show notes: 
News item 1/ Read More

Toxoplasmosis: A T.Gondii Host-pathogen interactome

This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More

TWiM 73 Letters

Mark writes:


Hello Team TWiM,


I’ve followed with interest your coverage of Michael’s research into use of copper to fight hospital infection. Of all the interesting papers covered in 2013, I think the one most actionable is episode 55, The Copper Room. His res... Read More

TWiP 54 Letters

Tommy writes:


Hi Vincent and Dickson,


I was listening to the new episode of TWiP (episode 52) and one of your listeners wrote in asking about tree parasites. While plant parasite is not my main field of research, I have written about one such pa... Read More

TWiV 227: Lacks security and bad poultry

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Hosts: Vincent Racaniello, Rich Condit, Read More

Sanctuary chimps show high rates of drug-resistant staph

Chimpanzees from African sanctuaries carry drug-resistant, human-associated strains of the bacteria Staphlyococcus aureus, a pathogen that the infected chimpanzees could spread to endangered wild ape populations if they were reintroduced to their natural habitat, a new study shows.

The study ... Read More

Inhibition of XMRV by a weapon of mass deamination

All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retro... Read More

TWiV 305: Rhymes with shinola

Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States.


Hosts:  Read More

The Great Epidemic - American Chestnut Blight

Merry Youle of Small Things Considered has a new post about the history of American chestnut blight and the scientific efforts to restock North America with these stately giants through the introduction of biological control agents or with more traditional plant breeding techniques.

Click so... Read More

Do We Need a Climate Solution for Indoors?

We typically spend close to 90 percent of our time inside - at school, work and home. While outdoor air quality is very important, so too is the quality of the air we breathe at home and the office. Yet most of us know very little about the condition of our indoor climate.  The chemicals ... Read More

TWiP 49 Letters

Jim writes:


Professors, you've discussed this idea before, but I thought you'd enjoy this nice summary from Nature:

http://www.nature.com/nature/journal/v491/n7423/... Read More

60 of the World's most memorable research papers

The Royal Society, founded in London in 1660 and one of the world's oldest scientific institutions, is marking the start of its 350th year by putting 60 of its most memorable research papers online. Several of these documents include papers by Sir Isaac Newton, Benjamin Franklin, and even Antoni... Read More
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