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Murphy’s Law in Science

Murphy’s law states that anything that can go wrong, will go wrong. Nowhere is this law more abundantly evident than in the life of a scientist. Here are just a few of the examples that I’ve witnessed:

•if you drop one tube from the whole rack, it will be the one that contained your most im... Read More

Craig Venter announces synthetic life

This TED video captures Caig Venter's official announcement that his team created the first fully functioning, reproducing cell controlled by synthetic DNA. He explains how they did it and why the achievement marks the beginning of a new era for science. Read More

BacterioFiles Micro Edition 40 - Prompting Plant Protectors

This episode: Plants call to bacteria for help!


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TWiP 102: Nursing eosinophils

The TWiPyzoites solve the case of the Uncommon Parasite, and discuss the role of eosinophils in promoting the growth of Trichinella in skeletal muscle.


Hosts:  Read More

BacterioFiles 210 - Archaea Acquired Alternative Abilities

This episode: Genes taken from bacteria may have been important for the evolution of distinct groups of archaea!


(7.4 MB, 8 minutes)


Show notes: 
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BacterioFiles 252 - Small Cells Supervise Circadian Cycles

This episode: In mice, high-fat diets affect their gut microbes, which in turn disrupts their circadian cycles and metabolic health!


(8.6 MB, 9.35 minutes)


Show notes: 
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TWiM 69 Letters

Gian writes:


Beloved TWiMers,


Did you see this paper in PLoS Computational Biology? It's mind-blowing. U. Maryland researchers found evidence for Acinetobacter and Pseudomonas nucleic acid integrated into human chromosomes and mitochondria, po... Read More

TWiP 94 letters


Elise writes:


Dear TWIP Trifecta,


How are you? It is lovely here in lower Manhattan, 82 F / 27 C with blue skies and not much in the way of humidity to make things wilt.


Since you are all going on the road, I’ll be on the edge of my seat waiting t... Read More

Zinc inhibits rhinovirus replication - profvrr does an experiment

I was given a package of zinc lozenges when I contracted a cold a few weeks ago. That got me interested in the effect of zinc on rhinovirus replication. As a consequence I began a series of experiments to understand the mechanism of inhibition of viral replication by this metal. It's unusual tha... Read More

TWiV 373: The distinguished virology career of Julius S. Youngner

 


Host: Vincent Racaniello 


Guest: Julius S. Youngner


Vincent... Read More

TWiP 103: Scroll down, please

The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.


Hosts:  Read More

TWiM 122 Letters

Hunter writes:


Greetings TWiM crew!
 
I recently learned of a new game (currently getting ready for Alpha and crowd funding) where players will edit microbes at the genetic level and pit them against microbes created by other players. The game is called... Read More

Host-Pathogen Interaction and Human Disease (Part 1) by Stanley Falkow, Ph.D.

Stanley Falkow, Professor Microbiology and Immunology; Geographic Medicine; Infectious Diseases, Stanford University School of Medicine, presents a lecture on host-pathogen interaction.

"Ninety percent of the cells humans carry are microbes. Only a few of the bacteria we encounter are pathoge... Read More

TWiP 105: Survival of the fattest

The TWiPanosomes solve the case of the Young Man from Anchorage, and discuss how cestode parasites increase the resistance of brine shrimp to arsenic toxicity.


Hosts: Vincent Racaniello Read More

Other Virus Like Things

Viruses may be referred to often as the smallest infectious things. But there are some smaller contenders. Some of the agents of plant disease lack even a viral coat and are merely small strings of plain, or "naked," RNA. These particles are called viroids. They are believed ... Read More

Estimating influenza-related sick leave in Norway: Was work absenteeism higher during the H1N1 pandemic?

The impact of influenza on work absenteeism is poorly documented. Researchers used data from the national registry and Norway Post AS (>14,000 employees) to explore sickness absence patterns from 2005/06 through 2009/10 in Norway. Annually, an estimated 2.868% (mean 95% confidence interval (CI):... Read More

What Microbe Are You? An Activity Designed for Our Youngest Scientist

This online “personality quiz” helps young learners understand the unconventional concept that most micro-organisms are beneficial; only a fraction are harmful. This activity matches the quiz-taker with the microbe that most closely reflects his or her personality. At the end of the quiz, studen... Read More

Virology course on Coursera

For fours years I have taught a virology course at Columbia University and have posted videos of each lecture on my website, virology.ws, and at iTunes University. Nearly 100,000 individuals have subscribed to my virology course at iTunes University. Now Columbia has signed an agreement with Cou... Read More

TWiP 110: Malaria at the Bronx Zoo

The TWiP trio visit the Bronx Zoo where Paul solves the case of the Four Year Old with Pulmonary Edema, and talks about his career as the Chief Veterinarian and Director of the Zoological Health program for the Wildlife Conservation Society.


Hosts:  Read More

BacterioFiles Micro Edition 53 - Bacteria Beta-oxidate Butanol Biofuel

This episode: Reversing a metabolic pathway is very effective!


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Do... Read More

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