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Viruses of protozoan parasites may exacerbate human disease

Many protozoan parasites (Trichomonas, Leishmania, Giardia, Plasmodium, Entamoeba, Nagleria, Eimeria, Cryptosporidium) are infected with viruses. These viruses do not infect vertebrates, but their double-stranded RNA genomes are sensed by the innate immune system, leading to inflammatory complic... Read More

Cyanobacteria: Growing a Green Future Around the Clock

Spencer Diamond and Britt Flaherty, PhD students at UCSD, Spencer in the Susan Golden Laboratory and Britt in the James Golden Laboratory, author a post on Small Things Considered about the green potential for cyanobacteria.

"With such famous bacteria as Escherichia coli and Bacillus subtili... Read More

Global warming may spur new fungal diseases (MWV37)

Watch Dr. Jeff Fox, Features Editor for Microbe Magazine talk with Arturo Casadevall, MD, Ph.D., the editor-in-chief of mB... Read More

BacterioFiles Micro Edition 131 - Stacking Sucker Symbionts

This episode: Some insects have bacterial symbionts with super-small genomes inside their cells, and some of these symbionts have their own internal bacterial symbionts!


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BacterioFiles 168 - Plentiful Plant Pathogen Partners

This episode: Multiple different fungi kill insects and give their nutrients to plant partners!


(8.3 MB, 9 minutes)


Show notes: 
Journal Paper


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Emerging Gastrointestinal Pathogen Linked With Human Fecal Contamination

A gastrointestinal pathogen associated with fecal contamination was present in 97 of 129 water samples taken from four beaches on the Lake Erie coast of Ohio according to research published in the August issue of Applied and Environmental Microbiology (click source to download a .pdf of the jour... Read More

Everyday Roles

Some people think it would be great if scientists could wipe out all the microbial bugs! Should we do it, and why or why not?


We get a lot of requests to track down the nasty bugs that are making people sick. It's true that some microbes cause health problems such as strep throat, chi... Read More

Behind the scenes: TWiV 202 at the University of Nebraska

We recorded This Week in Virology #202 at the University of Nebraska in Lincoln, Nebraska on 5 October 2012, as part of the 12th Annual Symposium in Virology. Terence Dermody, Shou-Wei Ding, Grant McFadden and I spoke about our research, and then we recorded TWiV with University of Nebraska viro... Read More

TWiV 253: I don't know anything about sorghum

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Hosts: Vincent Racaniello, Dickson Despommier, Read More

TWiV 230: Gene goes to Washington, flu chickens out

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Hosts: Vincent Racaniello, Rich Condit, Read More

A new coronavirus isolated from humans

A new coronavirus has been isolated from two individuals with severe respiratory illness. It is different from the SARS coronavirus, but health officials are nonetheless preparing for a rapid response should the virus be detected elsewhere. Read More

Development of an HIV-1 Specific Microbicide Using Caulobacter crescentus

A recent paper published in PLoS One looks at the strategy of manipulating surface proteins on the aquatic bacterium, Caulobacter crescentus, to prevent HIV infection.

Abstract:

The development of alternative strategies to prevent HIV infection is a global public health priority. Initial e... Read More

Paleovirology—Modern Consequences of Ancient Viruses

Here's an interesting essay published in PLoS Biology by Michael Emerman and Harmit S. Malik on paleovirology, a topic recently discussed by Welkin Johnson, on the Small Things Considered blog.


<... Read More

TWiM 65 Letters

Alexandra writes:


Dear TWIM-ers,


When I began listening to TWIV almost a year ago, I had just switched majors from philosophy to biology. I am now writing to you good people at TWIM at the end of my first undergraduate summer research gig, where I have had qui... Read More

BacterioFiles 158 - Partners Provide Protein

This episode: Different bacteria working together can thrive better than when working alone!


(9.9 MB, 10.75 minutes)


Show notes: 
News item/ Read More

TWiV 216: Processing VIRALGUUAACACCAGRNA

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Hosts: Vincent Racaniello, Alan Dove, Read More

BacterioFiles 181 - Spore-formers Smash Salmonella's Solanum Strongholds

This episode: Soil bacteria could help prevent food poisoning from bacteria in raw tomatoes!


(9.6 MB, 10.5 minutes)


Show notes: 
News item<... Read More

Time's Up

Merry Youle of the Small Things Considered blog has a new post up that looks at the phage-encoded holin timer and its function in a lytic infection.

"Holins are the smallest known biological timers. Timers, not clocks. Timers tick along, then go off after the specified interval. These small, ... Read More

Herpes simplex: Host Viral interactions database

This is a database of Herpes simplex (HSV-1) host/viral interactions hosted at WikiGenes. It provides a global snapshot of what the virus does in different compartments at all stages of the viral life-cycle from entry to exit. The database is interactive, and any researcher can edit the page or ... Read More

TWiV 95 Letters

Jim writes:

Some listeners might benefit from reading "The Treatment; why is it so difficult to develop drugs for cancer" in the May 17, 2010 issue of The New Yorker, a nine page article (pp 68-77).


This link goes to the digital edition ( http://archives.newyorker.co... Read More

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