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Viruses of protozoan parasites may exacerbate human disease

Many protozoan parasites (Trichomonas, Leishmania, Giardia, Plasmodium, Entamoeba, Nagleria, Eimeria, Cryptosporidium) are infected with viruses. These viruses do not infect vertebrates, but their double-stranded RNA genomes are sensed by the innate immune system, leading to inflammatory complic... Read More

Peptidoglycan remodeling and conversion of an inner membrane into an outer membrane during sporulation

I just finished listening to the TWiM 35 on LPS in Vibrio (among other topics). Dr. Elio Schaechter mentioned a field in Microbiology that I think is of great interest to the scientific community and should definitely be covered in a podcast. The topic is: Outer Membrane Biogenesis in Gram-negat... Read More

HAART has potential to diminish mother-to-child HIV transmission in cost-effective manner

A new paper publish in PLoS One concludes that programs that optimize adherence to highly-active antiretroviral therapy (HAART) through direct observation in pregnancy have the potential to diminish mother-to-child HIV transmission in a highly cost-effective manner. Read More

What They Look Like

hiv_illus Read More

TWiV 216: Processing VIRALGUUAACACCAGRNA



Hosts: Vincent Racaniello, Alan Dove, ... Read More

Everyday Roles

Some people think it would be great if scientists could wipe out all the microbial bugs! Should we do it, and why or why not?


We get a lot of requests to track down the nasty bugs that are making people sick. It's true that some microbes cause health problems such as strep throat, chi... Read More

BacterioFiles 160 - Residents Regulate RNA Response

This episode: Gut microbe communities can help regulate the immune response to pathogens!


(9.5 MB, 10.3 minutes)


Show notes: 
News item/ Read More

TWiM #78: A bacterium grows in Brooklyn

Hosts: Vincent RacanielloElio Schaechter, and Michael Schmidt.


Vincent, ... Read More

BacterioFiles Micro Edition 27 - Ingenious Influenza Immunizations

This episode: Flu vaccine made by bacteria!




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Microbe magazine--Audio interview with Anna Skalka

Anna Skalka of Fox Chase Cancer Center in Philadelphia, Pa., discusses research into the ages of various virus families with Jeffrey Fox of Microbe magazine Read More

The Effect of Universal Influenza Immunization on Mortality and Health Care Use

This is a postercast by Jeffrey C. Kwong, scientist at ICES.





























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From a food blender to real-time fluorescent imaging

Although Avery, MacLeod, and McCarty showed in 1944 that nucleic acid was both necessary and sufficient for the transfer of bacterial genetic traits, protein was still suspected to be a critical component of viral heredity. Alfred Hershey and Martha Chase showed that this hypothesis was incorrec... Read More

GEMINA - a web-based system of Genomic Metadata for Infectious Agents

GEMINA is a web-based system to identify infectious pathogens and their representative genomic sequences through selection of associated epidemiology metadata. Gemina supports the development of DNA signature-based assays for the detection of pathogens or sets of pathogen through the Insignia Si... Read More

Emerging disease: Looking for trouble

How do you persuade philanthropists to pay $1 million for every pathogenic human virus you discover? Anjali Nayar talks to 'virus hunter' Nathan Wolfe in Cameroon to find out.

Every day, more than 100 patients line up for treatment outside the bare cement walls of a rural health clinic in the... Read More

BacterioFiles 156 - Killing Chemicals Cancel Chemotherapy Quality

This episode: Gut bacteria seem to be important for different kinds of anti-cancer chemotherapy treatments!


(9.4 MB, 10.25 minutes)


Show notes: 
News item<... Read More

TWiV 264: We should do an all email show some day



Hosts: Vincent Racaniello, Alan Dove Read More

New Evidence for Polyomavirus BK Role in Prostate Cancer

Prostate cancer is the leading cause of cancer morbidity and the third greatest cause of cancer death among men in developed countries. A major question in cancer research has been whether virus infection plays a role in cancers of the genitourinary tract. Now a team of Swiss investigators has n... Read More

BacterioFiles Micro Edition 29 - Mid-air Microbial Mix

This episode: A sample of bacteria in city air!




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BacterioFiles 170 - Good Copper, Bad Copper

This episode: With guest host Susan Gardner! We discuss nitrogen-fixing plant-friendly bacteria that help plants grow in copper-contaminated soil, helping to clean it up!


(19.1 MB, 20.9 minutes)


Show notes: 
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The Invention of PCR

Few technical breakthroughs have changed the face of their field like the Polymerase Chain Reaction (PCR). Gene cloning, sequencing of complex genomes, DNA fingerprinting and DNA-based diagnostics are just some of the techniques that were either inefficient, crude or plain impossible before PCR.... Read More

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