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The Invention of PCR

Few technical breakthroughs have changed the face of their field like the Polymerase Chain Reaction (PCR). Gene cloning, sequencing of complex genomes, DNA fingerprinting and DNA-based diagnostics are just some of the techniques that were either inefficient, crude or plain impossible before PCR.... Read More

Water you waiting for? Find out more about choosing water filter membranes for DNA and RNA Isolation

We speak with many scientists each week who are working with filtered water for the isolation of microbial DNA and RNA. Because there are many choices for filter membranes, each with their own benefits, choosing the best one for your sample type and microbial load can be confusing. This article ... Read More

Lab Hacks: Lab equipment from the hardware store

While almost every lab has a small toolbox with some screwdrivers, pliers, and such, here are some tools that may not have obvious utility at the bench, but could make your life easier. Jode Plank, a Postdoctoral Fellow studying DNA repair at the University of California at Davis shares some of ... Read More

UCLA Pioneering Microbiology Educator and Author Discusses Innovative Teaching Methods

In this monthly interview series, meet Erin Sanders-Lorenz, an Adjunct Assistant Professor in the Department of Microbiology, Immunology, & Molecular Genetics at UCLA , co-author of the new book, "I, Microbiologist: A Discovery-based Course in Microbial Ecology and Molecular Evolution" and a lea... Read More

TWiV 72: Bucket of bolts

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On episode #72 of the podcast This Week in Virology, Vincent, Dickson, Alan and Rich explain CRISPR/Cas, the immune system of bacteria and archaea, how novel viruses are discovered by deep sequencin... Read More

How to Create an Effective PowerPoint Presentation

Presenting your work is a fantastic opportunity to get feedback on your project, demonstrate the significance of your results, and make the connections that will enhance your future career. And yet, how many incomprehensible lab meetings have we all sat through? How many seminars have you attend... Read More

Cutting the cold chain

No matter what advanced method is used to develop and produce vaccines, their efficacy is limited by old technology – the refrigerator. All viral vaccines must either be stored frozen, or kept at low temperatures. If they are not properly stored, they lose potency and do not confer protection ag... Read More

MTS45 - James Collins - Engineering Life: The Past and Future of Synthetic Biology

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4 student blogs that gladden an old man's heart

Moselio Schaechter at Small Things Considered highlights 4 student blogs that "gladden an old man's heart."

In Catalogue of Organisms, Christopher Taylor, a student of arachnids... Read More

Quick reference: Determining DNA Concentration and Purity

The most comprehensive way to evaluate DNA concentration and purity is to use both UV spectrophotometeric measurements and agarose gel eletrophoresis. This quick reference guide gives an overview of the information that can be derived from both.

This article is a clear and concise guide to th... Read More

Grad School is for Life, Not Just for Science

You are going to spend at least 4 years or more in graduate school, and around 3-5 years in a postdoc position. That’s a big chunk of your life, so apart from doing experiments, writing papers or your thesis and maybe doing some teaching, what else are you doing?

To paraphrase one of my favor... Read More

TWiP 5 - The nurse cell

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Vincent and Dick discuss the nurse cell, a unique structure formed in the host muscle by Trichinella species.


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Welcome to Extreme Biology! Violin-making and fungi

Welcome to Ms. Baker and her biology students extreme biology blog! This is perhaps one of the best high school student blogs I have ever seen.

In Extreme Biology, students post about "anything biology-related." Check out the post by Amy Ciardiello, a 9th grade violinist, who writes about "v... Read More

Anti-Bacterial Defences (Animation)

















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Hot Off the Press: Current Research Papers in Microbiology

In an ideal world, we would have time to read every great paper coming out in all the microbiology journals each month. Instead we have to focus our reading on the topics that directly impact our research. But reading papers from other fields can often help us to find new methods or generate id... Read More

TWiV 71: Please Mr. Postman

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On episode #71 of the podcast This Week in Virology, Vincent, Dickson, Alan and Rich answer listener questions about maternal infection and fetal injury, viral gene therapy, eyeglasses and influenza... Read More

Molecular Biology of Soil: an introduction

This article is the first in a series that discusses the issue surrounding the molecular studies of soil microbiology. In this first article we cover the basics of soil and why it is one of the most challenging samples to study and how to overcome those challenges. There are major differences im... Read More

The Microbiology of Food

Its seems as though every day there is another outbreak of bacterial contamination in food products, if you follow the twitter feed of the FDA and the posts on Microbeworld.org daily, as I do. Most recently, red pepper and Italian sausages were the source of salmonella contamination and had to b... Read More

C. elegans micro-injection

This video shows the process of injecting a a construct with gene manipulated DNA into a C. elegans worm. The outcome in this case was the rolling worm with the green fluorescent protein in it that localized to the body wall muscle, giving the worm the four green stripes along his body. Read More

XMRV not detected in Dutch chronic fatigue patients

The suggestion that the retrovirus XMRV is the etiologic agent of chronic fatigue syndrome (CFS) arose from a study in which the virus was found in 68 of 101 US patients. The virus was not detected in two independent studies of 186 and 170 CFS patients in the United Kingdom. A new Dutch study ha... Read More

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