No matter what advanced method is used to develop and produce vaccines, their efficacy is limited by old technology – the refrigerator. All viral vaccines must either be stored frozen, or kept at low temperatures. If they are not properly stored, they lose potency and do not confer protection ag... Read More
Moselio Schaechter at Small Things Considered highlights 4 student blogs that "gladden an old man's heart."
In Catalogue of Organisms, Christopher Taylor, a student of arachnids... Read More
The most comprehensive way to evaluate DNA concentration and purity is to use both UV spectrophotometeric measurements and agarose gel eletrophoresis. This quick reference guide gives an overview of the information that can be derived from both.
This article is a clear and concise guide to th... Read More
You are going to spend at least 4 years or more in graduate school, and around 3-5 years in a postdoc position. That’s a big chunk of your life, so apart from doing experiments, writing papers or your thesis and maybe doing some teaching, what else are you doing?
To paraphrase one of my favor... Read More
Vincent and Dick discuss the nurse cell, a unique structure formed in the host muscle by Trichinella species.
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Welcome to Ms. Baker and her biology students extreme biology blog! This is perhaps one of the best high school student blogs I have ever seen.
In Extreme Biology, students post about "anything biology-related." Check out the post by Amy Ciardiello, a 9th grade violinist, who writes about "v... Read More
In an ideal world, we would have time to read every great paper coming out in all the microbiology journals each month. Instead we have to focus our reading on the topics that directly impact our research. But reading papers from other fields can often help us to find new methods or generate id... Read More
On episode #71 of the podcast This Week in Virology, Vincent, Dickson, Alan and Rich answer listener questions about maternal infection and fetal injury, viral gene therapy, eyeglasses and influenza... Read More
This article is the first in a series that discusses the issue surrounding the molecular studies of soil microbiology. In this first article we cover the basics of soil and why it is one of the most challenging samples to study and how to overcome those challenges. There are major differences im... Read More
Its seems as though every day there is another outbreak of bacterial contamination in food products, if you follow the twitter feed of the FDA and the posts on Microbeworld.org daily, as I do. Most recently, red pepper and Italian sausages were the source of salmonella contamination and had to b... Read More
This video shows the process of injecting a a construct with gene manipulated DNA into a C. elegans worm. The outcome in this case was the rolling worm with the green fluorescent protein in it that localized to the body wall muscle, giving the worm the four green stripes along his body. Read More
The suggestion that the retrovirus XMRV is the etiologic agent of chronic fatigue syndrome (CFS) arose from a study in which the virus was found in 68 of 101 US patients. The virus was not detected in two independent studies of 186 and 170 CFS patients in the United Kingdom. A new Dutch study ha... Read More
A Comprehensive guide for microbiology, packed with lots of informative data readily usable by microbiologists around the world. Read More
Elio Schaechter of Small Things Considered asks if there is an evolutionary advantage for budding, where cell division is asymmetrical (yeast is an example), over binary fission, asexual reproduction by cell division?
"Binary fission is a most impressive invention. In one fell swo... Read More
Since electron micrographs first revealed the bullet-shaped morphology of vesicular stomatitis virus (a virus related to rabies virus), understanding the architecture has been elusive. It was known that the RNA genome is wrapped in a helical structure by the viral nucleocapsid (N) protein, but h... Read More
Broad spectrum antibiotics are available that act against a wide range of bacteria, including both gram-positive and gram-negative species. In contrast, our antiviral arsenal is exceedingly specific. Nearly all the known antivirals block infection with one or two different viruses. The discovery... Read More
On episode #70 of the podcast This Week in Virology, Vincent, Dickson, and Alan consider a broad spectrum antiviral against enveloped viruses, how a plant virus induces chemical signals in the host ... Read More
Chances are, in the course of your scientific career, you will encounter a common problem in research: losing time due to someone else’s mistake. Whether the problem is an incorrect strain or plasmid given to you by another lab, incorrectly made buffers or media from within your own lab, or, in ... Read More