Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown to have ... Read More
A new data resource for measuring the accuracy of metagenomic binning methods, created by in vitro-simulation of a metagenomic community, can be used to complement previous in silico benchmark studies. In constructing a synthetic community and sequencing its metagenome, researchers from the Univ... Read More
Hi guys really like the show even though some of it (not much) goes over my head. I also listen to twip and hope there will be a matching number of episodes to rival twiv. My name is Michael and I was talking to my dad the other day and he mentioned that he t... Read More
On episode #78 of the podcast This Week in Virology, Vincent, Alan, Dickson, and Rich talk about treating arthritis with a tanapox virus protein, Darwinian evolution of prions in cell culture, and the connect... Read More
Elio Schaechter of Small Things Considered defines the term "ontology" and why its destined to become part of every biologist’s vocabulary. Read More
A video from the DOE JGI '09 User Meeting on March 27, 2009 featuring Craig Venter's keynote talk "Reading and Writing the Genetic Code."
GEMINA is a web-based system to identify infectious pathogens and their representative genomic sequences through selection of associated epidemiology metadata. Gemina supports the development of DNA signature-based assays for the detection of pathogens or sets of pathogen through the Insignia Si... Read More
A new paper publish in PLoS One concludes that programs that optimize adherence to highly-active antiretroviral therapy (HAART) through direct observation in pregnancy have the potential to diminish mother-to-child HIV transmission in a highly cost-effective manner. Read More
It has always been assumed that plant viruses cannot infect animals, and vice versa, but plant viruses are known to be abundant in human faeces.
Now Didier Raoult at the University of the Mediterranean in Marseille, France, and his team think a pepper virus is making people sick, too.
They... Read More
Here's an interesting essay published in PLoS Biology by Michael Emerman and Harmit S. Malik on paleovirology, a topic recently discussed by Welkin Johnson, on the Small Things Considered blog.
<... Read More
Fluorescence-tagged Escherichia coli cells can be made to "blink" in unison by means of a constructed network of genes and proteins that coordinates oscillations within the growing cell population, according to Jeff Hasty and colleagues from the University of California, San Diego (UCSD) in La J... Read More
Deep sequencing – which identified a viral contaminant of the rotavirus vaccine Rotarix - could have revealed the presence of simian virus 40 (SV40) in the poliovirus vaccine, had the technique been available in the 1950s. Exposure of over 100 million Americans to SV40, and many more worldwide, ... Read More
Tracing the origin of an outbreak is a critical clue in curing a disease. But how can scientists track the beginnings of malaria, a disease that has been around for millions of years? Watch researcher Read More
Welkin Johnson, Assistant Professor of Microbiology and Molecular Genetics at Harvard Medical School and an Associate Blogger for Small Things Considered, ponders the "fossil record" of viruses:
"As a scientist fascinated with the evolutionary interplay between viruses and their hosts, I admi... Read More
In regard to your question as to cases of known alteration of host behavior by virus that increases the rate of contact among hosts (Twiv 70), the most dramatic example is given by rabies. This extraordinary virus can convert a neurologically and behaviorally... Read More
On episode #77 of the podcast This Week in Virology, Vincent, Alan, and Rich revisit circovirus contamination of Rotarix, then discuss poxvirus-like replication of mimivirus in the cell cytoplasm, and whether... Read More
The contamination of the rotavirus vaccine Rotarix with porcine circovirus 1 DNA was revealed by deep sequencing. The same technique was also used to demonstrate that oral poliovirus vaccine does not contain viruses that can cause poliomyelitis. Read More
Nanne Nanninga, Emeritus Professor of Molecular Cytology, Swammerdam Institute for Life Sciences, University of Amsterdam, The Netherlands, authors a guest post on Small Things Considered that questions whether van Leeuwenhoek actually observed yeast cells in 1680.
"It is common knowledge tha... Read More
Vincent and Dickson continue their discourse on tapeworms, covering the fish and dog varieties.
The third video of a three part lecture by Joseph DeRisi focuses on drug development for Malaria. Read More