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Twitter in Bioinformatics

This is a good demo on how to use the Twitter client TweetDeck to monitor real time information about bioinformatics (or any field for that matter). Read More

Antigen Switching in Malaria - A Classroom Activity

High school students and their teachers participate in a simple activity to demonstrate the interaction between the var antigens malaria parasites display and the patient's immune system. Read More

Some Like it Hot

A guest post on Small Things Considered by S. Marvin Friedman, Professor Emeritus, Department of Biological Sciences, Hunter College of CUNY, New York City, reviews the various mechanisms thermophiles and hyperthermophiles may use to proliferate at extreme temperatures. Friedman wonders whether ... Read More

El Podcast del Microbio" Nº 152 and 153. El experimento de Tuskegee (The Tuskegee Syphilis Experiment)



























El Podcast del Microbio" Nº 152 and 153 deals with the history of the infamous Tuskegee Syphilis Experiment and its follow-... Read More

BacterioFiles Micro Edition 27 - Ingenious Influenza Immunizations

This episode: Flu vaccine made by bacteria!


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TWiV 117 Letters

Martin writes:


Listen to this...it's incredible.


The pharma establishment is stomping on Dr. Andrew Wakefield in the same way they stomped on Peter Duesberg of UC Berkeley. In both cases Dues and Wakefield got it right, and the pharma establishment is shieldin... Read More

El podcast del Microbio Nº151. La vaca voladora (The flying cow)



























El Podcast del Microbio" Nº 151 is a resume of the article with the same name published in Moselio Schaechter's blog "Small... Read More

Are all virus particles infectious?

Chris Upton, a contributor to the virology toolbox, has raised an important point about multiplicity of infection:

Perhaps this is a place to bring up particle to pfu ratio? The above is great for when talking about phage, for example, when the ratio approaches 1. But with something like poli... Read More

El podcast del Microbio Nº150. El dúo asesino de las abejas (The Bee Dual Killer)



























El Podcast del Microbio" Nº 150 is dedicated to the microsporidia and the virus that causes Colony Collapse Disorder. El p... Read More

El podcast del Microbio Nº149. Physical Virology (Virología Física)



























El Podcast del Microbio" Nº 149 is based in the Nature Physics article by W Roos y G.J.L Wuite. El Podcast del Microbio Nº ... Read More

TWiP 21 Letters

Carolyn writes:

Dear Dick and Vincent,



Thank you very much for discussing my question on Crypto and the Miox disinfecting system on the last podcast. I appreciated the additional information.


My daughter sent me this link to a CDC report on killing cryp... Read More

TWiP 21 - The giant intestinal worm, Ascaris lumbricoides

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Vincent and Dickson review the biology and pathogenesis of Ascaris lumbricoides, one of the largest nematodes to infect humans.


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Multiple Displacement Technology Goes Digital: a method for enumeration of bacterial nucleic acid contamination in enzymes

Is bacterial DNA contamination in your whole genome amplification kit a problem? For microbiologists it sure is. WGA is a technique where the complete genomic content of a sample is amplified non-specifically and at a single temperature (isothermically). The presence of any contaminating DNA in ... Read More

The Fungus Detective - Robert Blanchette goes to extremes to solve microscopic mysteries

A profile of Robert Blanchette, professor of plant pathology at the University of Minnesota, and his interesting work on fungi and the degradation archaeological wood. Read More

TWiV 116: Cocaine, colonies, and chickens

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Hosts: Vincent Racaniello Read More

Multiplicity of infection

Multiplicity of infection (MOI) is a frequently used term in virology which refers to the number of virions that are added per cell during infection. If one million virions are added to one million cells, the MOI is one. If ten million virions are added, the MOI is ten. Add 100,000 virions, and ... Read More

Whole genome sequence of Borrelia burgdorferi...

Human Lyme disease is caused by a number of related Borrelia burgdorferi sensu lato species. We report here the complete genome sequence of Borrelia sp. isolate SV1 from Finland. Read More

TWiV 115: Color me infected

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Hosts: Vincent Racaniello Read More

TWiV 115 Letters

Vinayaka writes:


Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):


It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More

Derek Smith on antigenic cartography

Derek Smith, Professor of Infectious Disease Informatics, University of Cambridge, U.K., has developed a method for visualizing antigenic evolution by creating two-dimensional maps in a process called antigenic cartography. These maps are made with data that provide information on the antigen... Read More

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