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In search of a better diagnostic assay for emerging fungal pathogen Candida auris

Misdiagnosis can lead to severe consequences for patients, and is a serious clinical issue. The newly emerging Candida auris requires higher doses of antifungal medications to treat an infection than does C. albicans, highlighting the importance of proper diagnosis. Thus far, the most accurate d... Read More

TWiEVO 8: Everyone’s a little bit Neanderthal

Many years ago, Homo sapiens mated with Neanderthals. Today a small percentage of our genome remains Neanderthal, and in a study discussed on this episode of the science show This Week in Evolution, we show that some important genes of our innate immune response - the early response against path... Read More

TWiV 424: FLERVergnügen

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.


Hosts:  Read More

Association of maternal HSV-2 antibodies and autism spectrum disorder risk

Autism Spectrum Disorder (ASD) has no known single cause, and its growing incidence has led many researchers to study its influencing factors. While claims of vaccine relatedness are outright false, there are other variables that may contribute to a propensity toward ASD development, including e... Read More

TWiM #145: Anything but Academic

Vincent meets up with Catharine Bosio, Michael Merchlinsky, and Shilpa Gadwal at the ASM Biothreats meeting to talk about careers for scientists outside of the ivory tower.


Host: Vincent Racaniello


... Read More

Small RNAs regulate Bacteroides nutrient use

Just like you and me, bacteria have ‘favorite’ foods – though in the case of bacteria, 'favorite' translates to those which are energetically favorable or most accessible. Different bacteria have different preferences, based on their environments and the neighboring microbes that compete for or ... Read More

Disarming a pathogen's ability to cause disease

The anaerobic, Gram-positive Clostridium difficile is a big problem. It causes rampant diarrhea and tissue necrosis, with more than 150,000 annual cases in the United States alone. Many of the disease manifestations of C. difficile are mediated by two exotoxins that C. difficile produces: TcdA a... Read More

TWiV 428: Lyse globally, protect locally

The TWiVsters explain how superspreader bacteriophages release intact DNA from infected cells, and the role of astrocytes in protecting the cerebellum from virus infection.


Hosts: Vincent Racaniel... Read More

Toward better understanding of fecal microbiota transplants

In recent years, researchers have learned that gut microbiota play a role in a number of human diseases, including Clostridium difficile infection, irritable bowel syndrome, Parkinson’s disease, and autism spectrum disorder. The revelations have scientists hopeful that fecal microbiota transplan... Read More

TWiM #147: The Public Goods Dilemma

The TWiM hosts reveal why phosphorus is essential for fungal brain disease, and how bacteria kill local competitors to favor the evolution of public goods cooperation.


Hosts Vincent Racaniello Read More

BacterioFiles Special - Novozymes' Nathan Cude

This episode: An interview with Dr. Nathan Cude, team leader at Novozymes BioAg Alliance, working on finding and bringing to market soil microbes that can help crops grow!


(14.1 MB, 15.4 minutes)


Show notes: 
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TWiV 432: Conjunction junction, what's your function?

The TWiVites discuss Zika virus seroprevalence in wild monkeys, Zika virus mRNA vaccines, and a gamete fusion protein inherited from viruses.


Hosts: Vincent Racaniello Read More

10 Things You Need to Know about mSphereDirect

mSphereDirect is an exciting new pathway to publish your research! This groundbreaking new submission path puts you in control of getting your original research reviewed and published as soon as possible. We’ve prepared the most important things to keep in mind while preparing your manuscript s... Read More

Microbial Awards Season in Biology 350!

I like to encourage my students to explore the intersection between art and microbiology. Science + art = awesome! In any event, in this blog post, I describe two microbial art competitions in my microbiology course at the University of Puget Sound. I think my micronauts did some remarkable w... Read More

Dispatches from ASM Microbe - Saturday

Welcome back to Dispatches from ASM Microbe! Today we’ll continue Microbe 2016 highlights of the microbiome, focusing on the non-human microbiome research being presented during the conference.

As mentioned yesterday, commencement of the National Microbiome Initiative was met with great exci... Read More

Outbreak of H7N2 Flu in Cats

Many mBiosphere readers will know that the influenza A virus infects multiple species, and this ability to infect birds, humans, and other mammals such as pigs is one of the ways virions can exchange genetic information, leading to new viruses able to cause major outbreaks. However, few mBiosphe... Read More

Global Transcriptional Response of Acinetobacter baumannii to Light Exposure

While detection and reaction to light sources is a well-known process in environmental organisms exposed to diurnal light cycling, light detection also affects the biological processes of human pathogens. The human pathogen Acinetobacter baumannii, a microbe associated with hospital-acquired inf... Read More

Student-Made #SciArt In My Microbiology Lab

In this blogpost, take a tour of some of the artwork that students in my classes have made. I believe that creative approaches can complement learning! Read More

How to be a successful food borne pathogen: step 1, grow on food

Food microbiology is an important issue we cover on this blog, because food safety is vital to prevent foodborne illness. The use of technologies like whole-genome sequencing help identify and pinpoint the source of microbial contaminants, but how do microbes become contaminants in the first pla... Read More

ASMCUE Happenings 2016

No matter the niche field a scientist pursues, there is one aspect of almost all career paths that scientists have in common: teaching. Whether lecturing a quorum of undergraduates about bacterial genetics, mentoring a research fellow as they learn the lab protocols, or presenting an invited lec... Read More
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