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Pithovirus: Bigger than Pandoravirus with a smaller genome

A new virus called Pithovirus sibericum has been isolated from 30,000 year old Siberian permafrost. It is the oldest DNA virus of eukaryotes ever isolated, showing that viruses can retain infectivity in nature for very long periods of time. Read More

An outbreak of enterovirus 68

During the winter of 1962 in California, a new virus was isolated from the oropharynx of 4 children who had been hospitalized with respiratory disease that included pneumonia and bronchiolitis. On the basis of its physical, chemical, and biological properties, the virus was classified as an ente... Read More

ASM GM 2014 - Microbes and Cancer

Until recently cancers were seen as lifestyle and genetic diseases, brought on by exposure to carcinogens or a mutated gene. Recent studies are linking microbes to many diffe... Read More

Teaching Freshmen about Transformation, Drug Resistance, and Gene Regulation!

In this blog post, I describe how I use the commonly available pGLO plasmid to teach freshman students basic concepts about transformation, receptor recognition, drug resistance mechanisms, and gene regulation. Oh, and fluorescence via GFP! Read More

Implications of finding poliovirus in sewers of Brazil and Israel

Wild poliovirus has been detected in the sewers of Brazil and Israel. Fortunately, no cases of poliomyelitis have been reported in either country. Why is poliovirus present in these countries and what are the implications for the eradication effort?

Wild type poliovirus (e.g. not vaccine-deri... Read More

VIBRIO CHOLERAE O1 ISOLATEDFROM HUMAN STOOL

THIS IS VIBRIO CHOLERAE O1 OGAWA ISOLATED FROM HUMAN STOOL SWAB PLATED ON BILE SALT AGAR Read More

Attenuated influenza vaccine enhances bacterial colonization of mice

Infection with influenza virus is known to increase susceptibility to bacterial infections of the respiratory tract. In a mouse model of influenza, increased bacterial colonization was also observed after administration of an infectious, attenuated influenza virus vaccine. Primary influenza viru... Read More

BacterioFiles 195 - CRISPR/Cas Cuts Cancer Causers

This episode: Bacterial antivirus system could treat chronic herpes virus infections!


(10.9 MB, 11.9 minutes)


Show notes: 
Journal Paper


Read More

ASM GM 2014 - Windshield Wiper Fluid: A Source of Legionnaires?

A form of bacteria responsible for respiratory illness, including the deadly pneumonia known as Legionnaire's disease, may be able to grow in windshield washer fluid and was isolated from nearly 75% of school buses tested in one district in Arizona. The participant will discuss findings from ... Read More

Foldscope: Origami-Based Paper Microscope

PLOS ONE authors Cybulski, Clements and Prakash describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence microscopes. Merging principles of optical design with origami enables high-volume f... Read More

asm2014: Five Things Not to Miss at ASM’s 114th General Session

You don’t want to miss asm2014. We’ve compiled a list of five things not to miss at the 114th American Society for Microbiology General Session.

Click the "source" link or copy/paste this URL into your browser: http://blog.puritanmedproducts.com/bid/383376/asm2014-Five-Things-Not-to-Miss-at-... Read More

BacterioFiles 193 - Milk Modifies Monkey Microbes

This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!


(7.7 MB, 8.4 minutes)


Show notes: 
Read More

Report on Viruses Looks Beyond Disease

Recently, the American Academy of Microbiology released a new report, Viruses Throughout Life & Time: Friends, Foes, Change Agents that delves into the origin of viruses, the overlooked biological and microbial ecological role of viruses, and how these live forms have contributed to evolution. T... Read More

Remembering Carl Woese: A Memorial Issue of RNA Biology

The journal "RNA Biology" just published a memorial issue dedicated to the late, great Carl Woese. The entire issue is open access. I have a small contribution, but the entire issue is filled with great science, wonderful memories, and a fine celebration of a scientist who changed the way we l... Read More

Magical Monsoon:rAiNs and Geosmin

A Geosmin Story:
A Musty / Muddy smell - the earthy odour after a heavy spatter of rain is aesthetic to senses.
A poet sitting in such ambiance lets his thoughts to wander randomly and comes out with a sweet piece of write up.
An Artist can do wonders on his canvas flowing with the mood.
Man... Read More

BacterioFiles 190 - Bacteriophages Bust Biofilm Beacons

This episode: Engineered phages can both kill bacteria and disrupt their communications!


(14.8 MB, 16.2 minutes)


Show notes: 
Journal Paper


Read More

Nobel Laureates and Ebola virus quarantine

After the governors of New York and New Jersey decided that health workers who have returned from the Ebola virus outbreak in West Africa should be subject to a 21-day quarantine, two Nobel laureates entered the fray. Bruce Beutler feels that the quarantine is the right thing to do, while Peter ... Read More

Mineralization of sand particles boosts microbial water filtration

Mineral coatings on sand particles actually encourage microbial activity in the rapid sand filters that are used to treat groundwater for drinking, according to a paper published ahead of print in Applied and Environmental Microbiology. These findings resoundingly refute, for the first time, the... Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.


Hosts: Vincent Racaniello Read More

Probiotics vs Antibiotics? You're asking the wrong question.

'The question of whether someone should be taking a probiotic or an antibiotic is one I hear fairly frequently. The answer, in short, is that this isn't a question of either / or! At this stage in time, with this level of research on probiotics, it is not right to suggest one stops taking their... Read More
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