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Getting Started with MicrobeWorld

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TWiV 391: Whiter reefs, fresh breath

If you have always wanted to know what coral reefs and the human oral cavity have in common, listen as guests David Pride and Forest Rohwer talk about their work on the microbiomes and viromes of these two environments, and you'll also understand why mucus is cool.


Hosts:  Read More

BacterioFiles 263 - Germ Jettisoned Jellyfish Genes

This episode: Microscopic parasites of fish and worms actually came from jellyfish-like animals, after losing most of their genome!


(7.7 MB, 8.3 minutes)


Show notes: 
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TWiV 392: Zika virus!

Four virologists discuss our current understanding of Zika virus biology, pathogenesis, transmission, and prevention, in this special live episode recorded at the American Society for Microbiology in Washington, DC.


Host:  Read More

BacterioFiles 262 - Pathogen Polyketide Protects and Punishes

This episode: Clostridium bacteria that infect potatoes can both kill competitors and tolerate oxygen, thanks to the pink compounds they produce!


(12.4 MB, 13.5 minutes)


Show notes: 
Journal Paper:

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BacterioFiles 260 - Endoriftia Evacuate Expired Employers

This episode: Bacteria in hydrothermal vents that feed their host tubeworms evacuate when their hosts perish!


(9 MB, 9.8 minutes)


Show notes: 
Journal Paper:

Klose J, Polz MF, Wagner M, Schimak MP, Gollner S, Bright M. 2... Read More

TWiM #137: The battle for oxygen

Highlights of the Recent Advances in Microbial Control meeting in San Diego, and expansion of a gut pathogen by virulence factors that stimulate aerobic respiration.


Hosts: 


Vincent Racaniello, <... Read More

TWiM #135: Unruly individuals and their unruly friends

How critical illness alters the microbiome, and the consequences of a sewage spill into an aquatic environment, from the TWiM team.


Hosts: Vincent Racaniello, Elio... Read More

BacterioFiles 266 - Solar Cyborg Cells Capture Carbon

This episode: Adding exotic elements to convert spore-forming bacteria into light-capturing cyborgs that convert carbon dioxide into useful chemicals!


(9.7 MB, 10.5 minutes)


Show notes: 
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TWiV 396: Influenza viruses with Peter Palese

Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines.


Host: Vincent Racaniello 


Guest:&nbs... Read More

BacterioFiles 264 - Small Cells Stimulate Satiety

This episode: Proteins from gut bacteria seems to affect hunger and satiety in their (rodent) hosts!


(7.7 MB, 8.3 minutes)


Show notes: 
Ne... Read More

TWiV 393: Lovers and livers

The TWiVerati revisit possible sexual transmission of Zika virus, and reveal how a cell protein that allows hepatitis C virus replication in cell culture enhances vitamin E mediated protection against lipid peroxidation.


Hosts:  Read More

MMP #15: A Scientific Roadmap for Antibiotic Discovery

Host: Jeff Fox with special guests, Carolyn Shore and Ruben Tommasi.


Carolyn Shore of Pew Charitable Trusts in Washington, D.C., and Ruben Tommasi of Entasis Therapeutics in Waltham, Massachusetts, talk with Jeff Fox about what’s needed to identify and develop new antimicrobial agents... Read More

TWiV 401: Vector victorious

Zika virus spreads in the USA, a Zika virus DNA vaccine goes into phase I trials, and how mosquito bites enhance virus replication and disease, from the friendly TWiFolk Vincent, Dickson, Alan, and Kathy.


Hosts:  Read More

TWiV 398: Permission to be intuitive

Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation, cleavage and packaging of viral DNA genomes.


Host: Vincent Racaniello 


Guest: ... Read More

TWiM 133 Letters

Arthur writes:


Hello TWIMers!


I'm a graduate student working in mycoplasmology and I  must say I've been overjoyed to hear the past few episodes mention our tiny friends!


Elio's mention of their unique mechanism of moving ("Gliding Motility") made... Read More

TWiM #139: Frackibacter and sticky fingers

The TWiM team discusses microbial DNA found on ATM machines in New York City, and how hydraulic fracturing, or fracking, alters microbial ecosystems deep in the Earth.


Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson.


{audio}This Week in Mi... Read More

BacterioFiles 279 - Hijacker Heightened Hyphal Heterogeneity

This episode: Fungi control their cell's growth and division with a protein from a virus, unlike all other kinds of eukaryote!


(8.9 MB, 9.75 minutes)


Show notes: 


Read More

TWiP 122: If the thunder don't get you, the lightning will

The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community deworming on immunosuppression.


Hosts: Vincent Racaniello Read More

TWiM 129 Letters

Steven writes:


Dear Vincent et al,


Firstly, congratulations for keeping up such a wide range of thought provoking podcasts, and maintaining such a tremendous output. I find they all leave me with more questions than answers, which is, I think, a sign of good s... Read More

BacterioFiles 265 - Predator Protein Protects Predator

This episode: Predatory bacteria have a particular protein that protects them from their own prey-damaging enzymes!


(7.3 MB, 7.9 minutes)


Show notes: 
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