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TWiP 85: Channeling tryps

Vincent, Dickson, and Daniel explain how trypanolytic factor forms membrane channels to lyse trypanosomes, and present a new case study.


Hosts: Vincent Racaniello Read More

TWiP 84: Bigfoot

Vincent, Dickson, and Daniel consider the delivery of anti-trypanosome nanobodies to the tsetse fly via a bacterial symbiont, and present a new case study.


Hosts: Vincent Racaniello Read More

TWiV 304: Given X, solve for EBOV

 The TWiV team consults an epidemiologist to forecast the future scope of the Ebola virus epidemic in West Africa.


Hosts: Vincent Racaniello Read More

Interview with Dr. Amy Apprill

Amy Apprill is a researcher of Marine Microbiology. Her work focuses on the relation of Bacteria and Archaea to the health and ecology of marine animals. Her interest is on how animal associated microbes reflect the alterations in the surrounding marine environment that may be related to climate... Read More

The incubation period of a viral infection

The time before the symptoms of a viral infection appear is called the incubation period. During this time, viral genomes are replicating and the host is responding, producing cytokines such as interferon that can have global effects, leading to the classical symptoms of an acute infection (e.g.... Read More

Interview of Dr. Sikandar K Sherwani, Chairman of MAP

Mr. Sikandar K Sherwani, chairman of Microbiology Association of Pakistan (MAP).
He is a Lecturer of Microbiology (Sp. Immunology & Infectious Diseases) at the Department of Microbiology in Federal Urdu University for Arts, Science & Technology (FUUAST). He is also a research scholar at Immunol... Read More

TWiV 323: A skid loader full of viromes

Hosts: Vincent RacanielloDickson DespommierAlan Dove, Read More

ASM GM 2014 - The Next Emerging Threat

Over the past few decades there appears to have been a never-ending stream of emerging diseases from AIDS to SARS and now MERS. Predictions are that global warming will bring... Read More

TWiV 317: Brazil goes viral

On his second trip to Brazil, Vincent joins Eurico to speak with four young virologists, Gustavo, Cintia, Tatiana, and Suellen, about their work and their prospects for careers in science.


Host:  Read More

BacterioFiles 207 - Microbe Messages Mire Malaria Movement

This episode: Gut microbes may induce an immune response that protects against malaria!


(10.2 MB, 11.2 minutes)


Show notes: 
News item/... Read More

TWiV 286: Boston TWiV party

Vincent and Alan meet up with Julie and Paul at the General Meeting of the American Society for Microbiology in Boston, to talk about their work on the pathogenesis of poliovirus and measles virus.


Hosts: V... Read More

Acute flaccid paralysis of unknown etiology in California

In February 2014 I wrote about children in California who developed a poliomyelitis-like paralysis, also called acute flaccid paralysis or AFP. However, the cause of this paralysis was not known. The CDC has released its study of these cases and concludes “The etiology of AFP with anterior myeli... Read More

TWiV 324: Viruses in the miR may appear more numerous

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 325: Wildcats go viral

Hosts: Vincent Racaniello


Guests: Rollie Clem and Lorena Passarelli


{audio... Read More

Treatment of Ebola virus infection with brincidofovir

The Liberian man who was diagnosed with Ebola virus infection after traveling to Dallas, Texas, was treated with an antiviral drug called brincidofovir. This drug had originally been developed to treat infections with DNA-containing viruses. Why was it used to treat an Ebola virus infection? Read More

Let's declare WAAAR to antimicrobial resistance

We must change how antibiotics are used and adopt proactive strategies, similar to those used to save endangered species. Preservation of the efficacy of antibiotics and to stabilization of antibiotic-susceptible bacterial ecosystems should be global goals.

We urge all of you to participate i... Read More

TWiP 82 letters


Allan writes:


Dear Vincent, Dickson and Daniel,


I like your idea of a TWIP coffee mug prize (or maybe a mug discount).


In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

An unexpected benefit of inactivated poliovirus vaccine

The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV)... Read More

What we are not afraid to say about Ebola virus

In a recent New York Times OpEd entitled What We’re Afraid to Say About Ebola, Michaeal Osterholm wonders whether Ebola virus could go airborne:

You can now get Ebola only through direct contact with bodily fluids. If certain mutations occurred, it would mean that just breathing would put one... Read More

MWV94 - TWiM #99: Careers in Biodefense

Hosts: Vincent Racaniello


Guests: Maria Julia Marinissen, Read More

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