Spongiform encephalopathies are neurodegenerative diseases caused by misfolding of normal cellular prion proteins. A 2014 case of variant Creutzfeldt-Jacob prion disease in the United States was probably caused by eating beef from animals with bovine spongiform encephalopathy (BSE), or mad cow d... Read More
This episode: A conversation with Audiommunity hosts about a rabbit virus that may help treat cancer while preventing the treatment from killing the patient!
(39.2 MB, 42.9 minutes)
The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.
Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More
In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More
The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.
Hosts: Read More
Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More
This episode: Bacterial spores can survive atmospheric entry on an artificial meteorite!
(10.7 MB, 11.25 minutes)
This episode: Feeding mice high-fiber diets reduces their risk of allergic airway disease, even across generations!
(12.1 MB, 13.2 minutes)
Michael returns to help the TWiP trio solve the case of the Delusional African Expatriate, who then discuss the association of natural and induced antibodies in mice with differential susceptibility to secondary cystic echinococcosis.
Hosts: Read More
Host: Jeff Fox with special guest, Warren C. Ruder.
Warren C. Ruder of Virginia Polytechnic Institute and State University (Virginia Tech) in Blacksburg, Virginia talks with Jeff Fox about efforts to develop an electronic model system that incorporates a robot for a host and two sligh... Read More
Thank you for your lovely show. I started with Twiv after taking Dr Racaniello's online virology course, and have since moved to Twip and Twim, all very instructive and pleasant.
Yesterday my daily Twix dose... Read More
This episode: In mice, high-fat diets affect their gut microbes, which in turn disrupts their circadian cycles and metabolic health!
(8.6 MB, 9.35 minutes)
The TWiPanosomes solve the case of the Young Man from Anchorage, and discuss how cestode parasites increase the resistance of brine shrimp to arsenic toxicity.
Temperature in Oklahoma is 12 degrees C today and rainy.
My guess is Tunga penetrans which is native to South America. The black point at center of itchy toe lesion is the flea which are legs, spiracles and egg laying aparatus. Fema... Read More
An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More
The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More