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Getting Started with MicrobeWorld

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Is brushing your teeth harming your gut microbiome?

In the 1960’s, the microbicide triclosan, was introduced in the United States, and soon after, human weight started to increase dramatically. For some time, researchers have wondered whether triclosan could have played a role in disrupting endocrine dysfunction and contributing to the obesity ep... Read More

Burkholderia multivorans evolves in bursts in the lungs of cystic fibrosis patients

Leonilde M. Moreira, PhD, has been studying the Burkholderia complex for 15 years. The bacteria, known for causing pneumonia or septicemia in some individuals, can survive for prolonged periods in moist environments. During the last 10 years, it has become one of the more predominant bacteria se... Read More

Vibrio cholerae population structure changes in a matter of weeks

Although the Gram-negative bacterium Vibrio cholerae (right) is normally associated with human pathogenic disease, most V. cholerae cells spend their lives in an aquatic environment, and only a few of the many serotypes are able to cause disease. When strains acquire the right genetic makeup – s... Read More

TWiV 397: Trial by error

Vincent speaks with David Tuller about flaws in the U.K's $8 million PACE trial for chronic fatigue syndrome, and efforts to have the trial data released.


Host: Vincent Racaniello 


Gue... Read More

Whole-genome sequencing can help ID foodborne outbreaks

As we’ve seen in numerous cases in 2015, food contamination is a real issue for a number of different food types. Vegetable, meat, packaged, fresh – even pet food – we’ve seen too many examples of how bacteria can outsmart our best food safety practices. The Canadian government estimates 1 of ev... Read More

TWiV 407: Tar Heels go viral, part one

In the first of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on DNA viruses, and what they would be doing if they were not scientists.


Host:  Read More

TWiM #135: Unruly individuals and their unruly friends

How critical illness alters the microbiome, and the consequences of a sewage spill into an aquatic environment, from the TWiM team.


Hosts: Vincent Racaniello, Elio... Read More

TWiP 114: Plant potions perturb Plasmodium

The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.


Hosts: Vincent Racaniello Read More

MWV 105 - Understanding the Pathogenesis of the Emerging Zika Virus

Dr. Michael Diamond, 2016 Elizabeth O. King Lecturer, has worked for the past two decades investigating how viruses work, with a goal of defining basic principles of pathogenesis and host immune restriction. His talk in this podcast focuses on how his laboratory has studied three emerging mos... Read More

MMP #15: A Scientific Roadmap for Antibiotic Discovery

Host: Jeff Fox with special guests, Carolyn Shore and Ruben Tommasi.


Carolyn Shore of Pew Charitable Trusts in Washington, D.C., and Ruben Tommasi of Entasis Therapeutics in Waltham, Massachusetts, talk with Jeff Fox about what’s needed to identify and develop new antimicrobial agents... Read More

A biofilm model that accounts for cell aggregates

Whether you’ve Google-searched “biofilm” to learn more yourself, taken courses covering the subject, or are deeply embedded in biofilm-related research, you’ve probably encountered a model similar to the one below, which represents biofilm maturation. In the current model, a biofilm begins with ... Read More

TWiV 395: The cancer thief

From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy - using viruses to treat cancers. 


Hosts:  Read More

Using citizen science to engage students

Scientists and science educators now recognize the value in explaining what fields don’t understand, in addition to facts supported by years of experimental data. Citizen science projects, which emphasize accessibility of scientific technologies and methods for everyone, allow people without yea... Read More

Microbial communication over the airwaves

Jean-Paul Latgé originally wanted to know if he could test the breath of patients with Aspergillus infections for volatile compounds produced by the fungus. His group at the Pasteur Institute in Paris thought this might be a new way of diagnosing fungal culprits like Aspergillus fumigatus that o... Read More

TWiV 403: It's not easy being vaccine

The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine.


Hosts:  Read More

New American Academy of Microbiology Report provides recommendations for implementing NGS to clinical microbiology settings

This morning, the American Academy of Microbiology released a report, “Applications of Clinical Microbial Next-Generation Sequencing.” An event was held at the National Press Room to highlight its release. You can read more about the event here, or go here to read recommendations on NGS in a cli... Read More

BacterioFiles 265 - Predator Protein Protects Predator

This episode: Predatory bacteria have a particular protein that protects them from their own prey-damaging enzymes!


(7.3 MB, 7.9 minutes)


Show notes: 
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Foot and mouth disease virus: a global threat to agriculture

An important and sometimes overlooked issue of infrastructure is food security. American agriculture and related industries represent $1.5 trillion U.S. dollars and 17% of U.S. jobs. These workers provide the meat, eggs, dairy, and produce that many take for granted will end up on grocery shelve... Read More

Nonpathogenic viruses transferred during fecal transplants

Fecal transplants are increasingly being used for refractory Clostridium difficile and other gastrointestinal disorders. While fecal donors are screened for various infectious diseases, it is unclear whether viruses can in fact be transmitted during fecal transplants. Now a new study shows that ... Read More

TWiV 407: Tar Heels go viral, part two

In the second of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on RNA viruses, and what they would be doing if they were not scientists.


Host:  Read More

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