Despite increasing awareness of Klebsiella pneumoniae as a public health risk, there has been relatively little understood about its mechanisms of pathogenesis.
The bacterium, estimated to be the third most common cause of hospital-acquired infections in the United States in a recent study, c... Read More
This episode: Cyanobacteria in biocrusts produce pigments that heat their surroundings up to 10 degrees hotter!
(7 MB, 7.6 minutes)
The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.
Hosts: Read More
The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.
While walking through your house, you drop a granola bar you were eating. Quick – do you pick it up and eat it? Is the ground too dirty to eat from? Does the amount of time the food sits on the ground matter? Will more microbes gather onto the snack as you decide whether or not to continue noshi... Read More
Change does not come easily to most organizations, let alone to one with more than a century of history. Indeed, twice before ASM tried—and failed—to change its governance structure. This time, ASM members embraced change, realizing that ASM must become more modern and more nimble in its decisio... Read More
Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.
Function is often thought of as the tradeoff for high fashion, but who says you can’t have both? Fawn Jordan, 2016-2017 DC Fashion Incubator Designer in Residence, is seeking to unite the two to help protect women against potentially Zika-transmitting mosquitoes. Her recent collection combines t... Read More
Gruesome, ghastly, grisly. These are the words that popped into my head when I googled images of diabetic foot ulcers—one of the most common chronic wounds creating a silent and costly epidemic in healthcare.
Perhaps even more shocking is the mortality rate connected to these open wounds, wh... Read More
This episode: Adding exotic elements to convert spore-forming bacteria into light-capturing cyborgs that convert carbon dioxide into useful chemicals!
(9.7 MB, 10.5 minutes)
The TWiXers discuss a study on vertical transmission of Zika virus by Aedes mosquitoes, and uncovering Earth's virome by mining existing metagenomic sequence data.
"Hivi and his team of viruses (Ebola, Pox,..etc) believe they can win the battle, but the Virologists (who are real famous professors) beat them. However, new viruses pop-up, it will be a long battle. This makes the story very interesting and ever so engaging."
ACKNOWLEDGMEN... Read More
Of all the scientific results that my laboratory has produced over the years, I am most satisfied by those that maximally benefit the field. In this category falls the assay for determining the titer of Zika virus in plaque forming units per milliliter.
In ‘Counting Zika Virus’ I described o... Read More
There’s no question that foodborne disease is a serious problem. Illnesses from contaminated foods cause over 128,000 hospitalizations and 3,000 deaths each year in the United States. The Centers for Disease Control and Prevention estimates that one in six Americans suffers a food-related illne... Read More
Food-related microbiology can be one of the most fun - or least fun - ways to interact with microbes. In the ‘most fun’ category, scientists and non-scientists alike can use microbes to create delicious foods from fermentative processes; in the ‘least fun’ category, scientists and non-scientists... Read More
How is it that we are we able to devote so little of our personal time and energy to producing or acquiring the healthy, safe food that we consume multiple times every day? A large part of the reason we seldom worry about agricultural output is that most of us benefit enormously from modernized,... Read More
The human microbiome is the diverse population of microorganisms that live on and in the body. Many thrive on the skin and in the mouth, but the majority live in the intestines. Over the last decade or so, microbiologists have become increasingly aware of how a person's microbial mix likely play... Read More
I teach Microbiology at the University of Puget Sound every fall semester. The swiftly changing field of microbiology has depth and breath...and I was interested to learn what my students thought of the topic at the beginning of the first day of class. We will revisit this subject at the end o... Read More
Antimicrobial resistance has been a growing concern in the health care community. But a publication by Chinese researchers in The Lancet Infectious Diseases last fall kicked things up a notch. The work found the mcr-1 gene, which confers resistance to the antibiotic colistin, in Escherichia coli... Read More