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TWiV 336: Brought to you by the letters H, N, P, and Eye

 Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler


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The TWiVsters explore mutations in the interferon pathway associated with severe influenza in a child... Read More

Discovery of the Sixth DNA base?

Scientist has described the possible existence of sixth DNA base, the methyl-adenine (mA) this week.

Deoxyribonucleic acid (DNA) is a polymer of nucleotides, which encodes every genetic information of living existence. The entire genetic information are stored within DNA as the form of millio... Read More

Designer viruses for killing tumor cells

A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved.

Adenovirus CG0070, designed to treat bladder cancer, and adenovirus O... Read More

Freshman Biology Creative Projects

I am a big believer that different pedagogical approaches can "reach" different students. In most of my classes, I give students an optional assignment: come up with a creative project that explores some aspect of class. This takes several steps. First, I make the students come up with an ide... Read More

TWiM #103: The battle for iron

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 103 Letters

Bailey writes:


Hey Vincent, Elio, Michele and Michael!


I'm a first year microbiology graduate student at UC Berkeley and an avid listener of twim. Elio's snippet from the most recent podcast reminded me of a personal anecdote that might be useful to share with... Read More

Smartphone adapted for use as a video microscope to detect parasites in blood in under resourced communities

This is a good news story all around. UC Berkeley engineers, Michael D'Amrosio and Matthew Bakalar (UC Berkeley Bioengineering) with medical personal from NIAID, Dr. Thomas Nutaman and his collaborators from Cameroon and France collectively took the omni-present global resource, a standard smar... Read More

TWiV 335: Ebola lite

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiP 88: French foreign lesion

Vincent, Dickson, and Daniel discuss how a secreted protein from the protozoan parasite Theileria transforms its host cells via a cellular proto-oncogene.


Hosts:  Read More

TWiP 88 letters

 


Robin writes:


Cutaneous leishmaniasis.
CL has been endemic in Italy at a relatively constant level since the 1970s, in the same areas that are endemic for VL. CL is largely underreported to the MoH. Only cases that are diagnosed and treated in hosp... Read More

A new cell receptor for rhinovirus

Rhinovirus is the most frequent cause of the common cold, and the virus itself is quite common: there are over 160 types, classified into 3 species. The cell receptor has just been identified for the rhinovirus C species, which can cause more severe illness than members of the A or B species: it... Read More

BacterioFiles 212 - Ghosts Get Good Guarding

This episode: Bacterial ghosts could make good vaccines for different things!


(9.8 MB, 10.7 minutes)


Show notes: 
Journal Paper


Read More

Retroviral influence on human embryonic development

About eight percent of human DNA is viral: it consists of retroviral genomes produced by infections that occurred many years ago. These endogenous retroviruses are passed from parent to child in our DNA. Some of these viral genomes are activated for a brief time during human embryogenesis, sugge... Read More

TWiV 334: In vino virus

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiM #102: Happiness is the spore-formers in your gut

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 102 Letters

Dave writes:


TWIM Comrades--
I first want to compliment you on one of my most listened to podcasts, and one that I actually know what is being presented most of the time.


Now about the term Talmudic.
Do we need a name that is a legal commentary on th... Read More

Design, engineering and utility of biotic games

First of the three videos related to research article appearing in Lab on a Chip. I. H. Riedel-Kruse et al "Design, Engineering and Utility of Biotic Games". Read the article by clicking "source" above.

From the abstract:

Games are a significant and defining part of human culture, and thei... Read More

Streptococcus pyogenes

Throat swab of (5) years old child from emergency department for culture and sensitivity clinical summary scarlet fever.

Streptococcus pyogenes, or Group A Streptococcus, is a spherical, Gram-positive bacterium.[1] S. pyogenes displays streptococcal group A antigen on its cell wall and typic... Read More

Describing a viral quasispecies

Virus populations do not consist of a single member with a defined nucleic acid sequence, but are dynamic distributions of nonidentical but related members called a quasispecies (illustrated at left). While next-generation sequencing methods have the capability of describing a quasispecies, the ... Read More

TWiP 87: Stumped by pinworm

Vincent, Dickson, and Daniel review new insight into antigenic variation in trypanosomes, reveal the difficult solution to the last case study, and  present another mystery for your solving.


Hosts:  Read More

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