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Chemistry: A festive ferment

Rare is the holiday meal that does not owe many of its pleasures to invisible cooks with tongue-twisting names. Do you enjoy charcuterie and pickles? Bread with cultured butter? A drizzle of vinaigrette on this or that? A bit of cheese? Some chocolates? Wine, beer or cider? Then raise a glass to... Read More

TWiV 265: This year in virology



Hosts: Vincent Racaniello, Alan Dove Read More

BacterioFiles Micro Edition 148 - Engineered Escherichia Enzyme Enhances Environmentalism

This episode: Engineered bacteria could help capture CO2 and convert it into a solid form for storage!


(7.3 MB, 8 minutes)


E. coli engineered to produce the enzyme carbonic anhydrase, which converts carbon dioxide to bicarbonate and then to calcium carbonate,... Read More

TWiV 264: We should do an all email show some day



Hosts: Vincent Racaniello, Alan Dove Read More

TWiP 64 letters

Richard writes:


Good morning, day, evening (depending on your time of day). Esteemed professors!


Firstly my weather report, for Weston super Mare, uk.


It is currently 3 centigrade (feels like 2C), dew point 4C, humidity 78%, there has been 1m... Read More

TWiP 64: Three new ways to prevent malaria



Hosts: Vincent Racaniello and Dickson Despommier


Vincent and Dickson review... Read More

MERS-CoV genome found in dromedary camels

Middle Eastern respiratory syndrome coronavirus (MERS-CoV), first identified in the fall of 2012 in a Saudi Arabian patient, has since infected over 160 individuals, causing 71 deaths. Identifying the source of infection is important for efforts to prevent further infections. Recently two studie... Read More

Viral gifts

If you are looking for the perfect present for that infectious person in your life, there are many microbe-themed possibilities. Here are some suggestions, from t-shirts, to watercolors, glass sculptures, and paper to wrap it in. Read More

TWiM #70: A paroxysmal cough

Hosts: Vincent RacanielloElio SchaechterMichael Schmidt and Read More

Mundo de los Microbios - Episodio 106 - Ricardo Santos

Aunque el género Mycobacterium es asociado a infecciones tales como la lepra y la tuberculosis, hay un gran número de especies que son por lo general no patogénicos o patógenos oportunistas. En el episodio de hoy tenemos al Dr. Ricardo Santos del Instituto Superior Técnico de Lisboa, Portugal... Read More

BacterioFiles Micro Edition 147 - Clostridium Conquers Colleagues

This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!


(7 MB, 7.5 minutes)


When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More

TWiV 263: Game of clones



Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove Read More

Molecular mechanisms of resistance

The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.

Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

Handling the cholera outbreak of 1854

This article discusses the famous pump handle that John Snow may or may not have had removed ... read the article to get the true story. From medical historian Peter Vinten-Johansen. Read More

BacterioFiles Micro Edition 146 - Engineered Escherichia Eliminates Enemies

This episode: Scientists engineered E. coli to seek and destroy pathogens!


(10 MB, 11 minutes)


A bacterium can sense pathogens in the body, swim toward them, and release a deadly biofilm-busting payload. This process is called pseudotaxis, and could be modified for many... Read More

TWiV 262: Wrong form, right professor



Host: Vincent Racaniello


Guest: Read More

Remembering a Microbial Hero™: The Late, Great Abigail Salyers.

Here I remember a person who a great deal of influence on my views about microbiology in the classroom, and the laboratory: the late Abigail Salyers. RIP, Abigail. Read More

Some "Rules" for Academia and Research

In this blog post, I describe some "rules for academics" as well as my own "rules for research." I hope that readers find them useful and perhaps a bit humorous. Read More

BacterioFiles Micro Edition 145 - Clostridium Converts Cortisol

This episode: Gut bacteria may convert cortisol into important human hormones!


(6 MB, 6.5 minutes)


Note: Episode 144 is now available too. Sorry about that. Not sure what went wrong there, but it is regrettable.


A minor player in the gut, Clostridium scindens,... Read More

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