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Staph's Virulence and Resistance Genes Can Transfer in Pairs

Scientists studying Staphylococcus bacteria, including methicillin-resistant S. aureus (MRSA), have discovered a potent staph toxin responsible for disease severity. They also found the gene for the toxin traveling with a genetic component of Staphylococcus that controls resistance to antibiotic... Read More

TWiV 106: Making viral DNA II

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On episode #106 of the podcast This Week in Virology, Vincent, Dickson, and Rich continue Virology 101 with a second installment of their discussion of how viruses with DNA genomes replicate their g... Read More

Understanding cell organization

Franklin M. Harold, Department of Microbiology, University of Washington has authored an interesting guest post on www.SmallThingsConsidered.us that examines the process of cell structural organization and assembly:

"Structural organization is one of the most conspicuous features of cells, a... Read More

TWiV 163: What Rous wrought

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Hosts: Vincent Racaniello, Dickson Despommier Read More

TWiM 2 Letters

Barbara Hyde writes:

In the discussion of copper, it should be noted that copper has long been added to marine bottom paints as an anti-fouling agent. Now however there is concern about deleterious environmental effects from its leaching out into the waters.

Barb... Read More

TWiV 183 Letters

Joe writes:


How cool is that to be listening to you all reading my emails with Peter Sandman while I am stuck in traffic.


I loved the discussion and want to send a big thank you to Michael for joining in and giving us the missing perspective of what the NSABB ... Read More

Virus Adaptation and Treatment - A paradigm linking herpes- virus immediate-early gene expression apoptosis and myalgic encephalomyelitis chronic fatigue syndrome

Multiple viruses have been linked to ME/CFS suggesting that multiple pathogens cause the same disease or several diseases with core signs and symptoms. Or if you are on Team XMRV /MuLV - a retrovirus could be the mastermind. No matter how you slice it in science, questions beget theories which... Read More

TWiV 169: Epidemiology causes conclusions

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Hosts: Vincent Racaniello, Dickson Despommier Read More

TWiV 190 Letters

Cara writes:


Hello Vincent and Team TWIV,


I love Virology, and it is with much chagrin that I admit I have only recently started listening to TWIV. However I have tried to mend the error of my ways by: 1) proselytizing the benefits (keeping up-to-date with and... Read More

TWiV 115: Color me infected

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Hosts: Vincent Racaniello Read More

Conserved amino acid markers from past influenza pandemic strains

A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More

Automating the survey of protein locations: the trials and tribulations

An article by Alan Derman, Project Scientist in Joe Pogliano’s lab at the University of California at San Diego, published on the Small Things Considered blog presents a point-by-point analysis of a paper "Quantitative genome-scale analysis of protein localization in an asymmetric bacterium" pub... Read More

TWiV 112 Letters

Jennie writes:


I love your show very much and this is not my first comment. I load firewood and paint as I listen to you guys, thanks so much for the inspiration over what is becoming years. I'm not an audio learner, though my mind is quite stimulated by what I hear. ... Read More

Small fragments of viral nucleic acid cross borders in monkey meat

The finding of viral nucleic acid sequences in illegally imported wildlife products has attracted the attention of the New York Times, which published an article entitled From the jungle to J.F.K., viruses cross borders in monkey meat. Read More

Finding the key to strengthening the immune response to chronic infections

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as s... Read More

The Attendee's Guide to Scientific Meetings

Julian Davies, Professor emeritus at the University of British Columbia and a Fellow of the Royal Society, has authored a humorous post on the Small Things Considered blog on the various methods an attendee of a scientific meeting can employ to enhance "maximum satisfaction and poise" one gets o... Read More

Building the perfect bug

This past February I was interviewed by the Australian Broadcasting Company on the topic of the Fouchier and Kawaoka experiments on avian influenza virus H5N1. The video, Building the Perfect Bug, has been released by Journeyman Pictures and includes interviews with S.T. Lai, Laurie Garrett, Mic... Read More

Norton Zinder, 1928-2012

Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More

The Three Faces of Thiomargarita

Merry Youle of Small Things Considered has authored a post that looks at Thiomargarita spp.

"Non-motile Thiomargarita was first discovered in 1999 off the Namibian coast, thus was named T. namibiensis. Its cells are large spheres, arranged in chains, each chain enclosed in a mucous sheath. Av... Read More

Audio interview by Microbe magazine Current Topics and Features editor Jeff Fox with Douglas Theobald of Brandeis University.

Microbe magazine Current Topics and Features Editor Jeff Fox talks with Douglas Theobald of Brandeis University about Theobald's work testing the he notion of a universal common ancestry (UCA) for all species.
Read More

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