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India polio-free for one year

A year has passed since the last reported case of poliomyelitis in India, which occurred on 13 January 2011 in a two year old girl in Howrah, West Bengal. Read More

Publication of XMRV papers should not be blocked

The findings by the NIH and FDA that XMRV is associated with chronic fatigue syndrome has been accepted for publication by the Proceedings of the National Academy of Sciences (PNAS). Release of the article has been blocked by PNAS due to work carried out by the US Centers for Disease Control and... Read More

TWiV 115 Letters

Vinayaka writes:


Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):


It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More

TWiV 101 Letters

Russ writes:


I think this image from www.3d4medical.com is great!


This is a cool app for the iPad. This would make a great pick of the week


Russ


Julian writes:<... Read More

The Rise of Community-Associated MRSA

This teleconference is sponsored by the American Society for Microbiology and will review the history and importance of methicillin-resistant Staphylococcus aureus (MRSA) with a primary focus on the emergence of community-associated MRSA (CA-MRSA). The phenotypic and molecular identification of ... Read More

TWiV 124 Letters

Norm writes:


First, I love your podcasts.


You guys are constantly grousing about the lack of research funding.


I was curious.


NIH, funding has risen every year since 2000, from $17B to the current $31B (supports 325,000 researchers)


NSF... Read More

Automating the survey of protein locations: the trials and tribulations

An article by Alan Derman, Project Scientist in Joe Pogliano’s lab at the University of California at San Diego, published on the Small Things Considered blog presents a point-by-point analysis of a paper "Quantitative genome-scale analysis of protein localization in an asymmetric bacterium" pub... Read More

XMRV, prostate cancer, and chronic fatigue syndrome

Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so ... Read More

Conserved amino acid markers from past influenza pandemic strains

A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More

Ferreting out influenza H5N1

A laboratory in the Netherlands has identified a lethal influenza H5N1 virus strain that is transmitted among ferrets. These findings are under review by the National Science Advisory Board for Biosecurity (NSABB) to ensure that they do not constitute a threat to human health. Meanwhile both the... Read More

TWiV 87 Letters

James writes:


Dear TWIV,


I've really enjoyed hearing about the paths you and your guests took to enter the fields of virology and parasitology.


I was wondering if Dr. Dove could talk for a few minutes about how and why he decided to transition into sci... Read More

TWiV 166 Letters

Eric writes:


Hello Professors,


Thanks again for all the effort and care you invest into your podcasts. I'm writing today to suggest a pick of the week: The Nature of Things with David Suzuki. Suzuki, one of Canada's scientist/rock-stars, hosts... Read More

Cryptic Life in the Antarctic Dry Valleys

Small Things Considered co-blogger Merry Youle has a post about the diversity of life in McKelvey Valley, a broad, glacially-carved pass just west of McMurdo Sound in Antarctica. Her writing is inspired in part by a recent paper from the University of Hong Kong (See Read More

Bacteria Galore by Sunday at Four

This is a great online children's book about the role of bacteria in our lives by Dr. Mel Rosenberg for ages 3+. Read More

Aaron J. Shatkin, 77

Aaron J. Shatkin was well known for his work on reoviruses beginning in the 1960s in his laboratory at the Roche Institute of Molecular Biology in Nutley, NJ and then at Rutgers University. He was among the first to appreciate that virus particles contained many different enzymes, such as RNA po... Read More

TWiV 152 Letters

Atila writes:


Dear TWiVers,


I have heard recently that some types of herpes virus may protect us from bacterial infections. This made me remember of myxomavirus, viral oncotherapy and how tumor cells have a compromised immune response. Do you think it is possi... Read More

A mad cow in America

A dairy cow in California is the fourth known American case of mad cow disease, which is caused by prions, infectious agents composed only of protein (the story hit the press the day after my lecture on this type of illness). Unlike viruses, prions have no nucleic acid and no protective coat. Bu... Read More

MicroRNAs and Retroviral Integrity

Jamie Henzy, a postdoctoral researcher at Boston College, has authored a post on Small Things Considered that explores the shady world of the deltaretrovirus genus.

"Among retroviruses, the deltaretrovirus genus is something of a shady bunch, its members lurking in the shadows, causing troubl... Read More

Are there viruses of arsenic-utilizing bacteria?

A salt-loving (halophilic) bacterium which can grow in medium containing arsenic instead of phosphorus has been selected from the microbial community of Mono Lake in California. Arsenic (As) is a chemical analog of phosphorus and is usually toxic because it can enter metabolic pathways in the pl... Read More

New Elsevier Slogan: “It’s All about The Benjamins”

Rich Condit found an article highly critical of the original Wakefield study (claiming a link between MMR vaccine and autism) which was published in the same issue of Lancet. He asked the publisher, Elsevier, to open up the article to non-subscribers so he could recommend it as a pick of the wee... Read More
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