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Conserved amino acid markers from past influenza pandemic strains

A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More

TWiV 165: The email zone



Hosts: Vincent Racaniello, Dickson Despommier Read More

Is it Ebolavirus or Ebola virus?

When I drafted my article for TakePart (Don’t Panic – Ebola Isn’t Heading For You), I used the term ‘ebolavirus’ throughout, but the editors changed every instance to ‘Ebola virus’. Understanding which term is correct is far more complicated than you might imagine. Read More

Propose a Topic for asm2012 - 112th General Meeting of ASM

Are you interested in proposing an interdisciplinary topic with maximum appeal? Do you have an idea for a core colloquium or symposium of scientific significance? ASM's General Meeting Program Committee is soliciting suggestions to help build the program for asm2012 in San Francisco, June 16-1... Read More

Bacteria Galore by Sunday at Four

This is a great online children's book about the role of bacteria in our lives by Dr. Mel Rosenberg for ages 3+. Read More

Kawaoka paper published on aerosol transmission of H5 influenza virus in ferrets

One of two papers on avian influenza H5N1 virus that caused such a furor in the past six months was published today in the journal Nature. I have read it, and I can assure you that the results do not enable the construction of a deadly biological weapon. Instead, they illuminate important requir... Read More

Is Vilyuisk encephalitis a viral disease?

A type of human encephalitis – an infection of the brain – has been known to affect the indigenous people living in the Sakha Republic of Russia since the mid-1800s. The available clinical and epidemiological evidence suggests that the disease is caused by a pathogen, but proving this has been d... Read More

Are there viruses of arsenic-utilizing bacteria?

A salt-loving (halophilic) bacterium which can grow in medium containing arsenic instead of phosphorus has been selected from the microbial community of Mono Lake in California. Arsenic (As) is a chemical analog of phosphorus and is usually toxic because it can enter metabolic pathways in the pl... Read More

TWiV 167: It starts with a cough



Hosts: Vincent Racaniello, Dickson Despommier Read More

Happy as a clam? Maybe not.

The expression “Happy as a Clam” comes with new meaning as hepatitis A virus has been detected in clams, mussels, and oysters in markets for human consumption. As bivalve shellfish are excellent bio-accumulators of contaminants and chemicals, it is no surprise that they also harbor waterborne vi... Read More

TWiV 179 Letters

Ebrahim writes:


Dear Dr. Racaniello


I was watching the conference in Dublin and I wanted to thank you for sharing my e-mail with the people in the panel, since I saw how nice it was for me to reach the specialists with that ease through TWIV.<... Read More

TWiV 188 Letters

Judi writes:


To our TWIV leaders!


If you have a mac with Apps, please go to the app store and download cell images.... I think you'll have a great time going through them.


One other thing - I listened to your show on science reform with interest but I ... Read More

Alzheimer''s disease plaques and tangles: Repositories of a herpes simplex/immune system battle leading to neuronal destruction

The protein components of the plaques and tangles seen in the Alzheimer's disease brain offer a clue to the origins of the disease: It turns out that they are heavily enriched in human proteins used by herpes simplex during its life cycle: Many immune system related proteins are also found in th... Read More

TWiP 33 Letters

Howie writes:



Twivers,


Great podcast!!!


A while ago, Dick made a comment along the lines that Sir... Read More

TWiP 29 Letters

Dylan writes:

Dear Professors Racaniello and Depommier,


I hope this email finds you both in good health. I am a second year medical student from Ireland studying at the University of Cambridge, UK and I have been following the TWiP series with considerable interest... Read More

David and Goliath: How one cytokine may take down influenza

Recent research has suggested a new method of flu prevention and treatment: the administration of granulocyte macrophage-colony stimulating factor (GM-CSF) to the lungs of mice significantly reduced flu symptoms and prevented mortality after a lethal dose of influenza virus. GM-CSF helps the bod... Read More

TWiV 151: Dear TWiVers



Hosts: Vincent Racaniello, Alan Dove Read More

Whole genome sequence of Borrelia burgdorferi...

Human Lyme disease is caused by a number of related Borrelia burgdorferi sensu lato species. We report here the complete genome sequence of Borrelia sp. isolate SV1 from Finland. Read More

Interesting Rhinovirus Study + Bonus Chicken Soup Recipe

This 2000 paper, published in Chest, shows that chicken soup is capable of inhibiting neutrophil chemotaxis in vitro, thus providing some evidence for the soup's traditional role as a home cure for respiratory infections.

Helpfully, the soup recipe used in the study is also included. And it ... Read More

Fighting Disease: Researching the History and Biology of Vaccines (resource for teachers)

What is a vaccine, and why do we need them? How do vaccines work, and how were they developed? In this lesson, students gauge their previous knowledge about vaccines. They then explore the history and biology of vaccines and create educational posters on the nature of vaccines and public opinion... Read More

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