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TWiV 159 Letters

Jenny writes:


Hi Vince and the rest of the TWIV-cast!


You might have come across this news already, but it would be interesting to hear the TWIV gang's take on this study done by Fouchier's group from the Netherlands.


Read More

A spike for piercing the cell membrane

Some viruses that infect bacteria (bacteriophages) deliver their DNA into the host cell with an amazing injection machine. The tailed bacteriophages (such as T4, illustrated) store their DNA in a capsid attached to a long tail tube that is surrounded by a sheath. At the bottom of the tube is a b... Read More

TWiV 115 Letters

Vinayaka writes:


Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):


It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More

Publication of XMRV papers should not be blocked

The findings by the NIH and FDA that XMRV is associated with chronic fatigue syndrome has been accepted for publication by the Proceedings of the National Academy of Sciences (PNAS). Release of the article has been blocked by PNAS due to work carried out by the US Centers for Disease Control and... Read More

Automating the survey of protein locations: the trials and tribulations

An article by Alan Derman, Project Scientist in Joe Pogliano’s lab at the University of California at San Diego, published on the Small Things Considered blog presents a point-by-point analysis of a paper "Quantitative genome-scale analysis of protein localization in an asymmetric bacterium" pub... Read More

XMRV, prostate cancer, and chronic fatigue syndrome

Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so ... Read More

TWiV 122 Letters

Luke writes:


Hello TWiV hosts,


I'm currently working as a technician in the biochemistry and molecular biophysics department at Columbia, having just received my BA from here in the Spring. First of all, I'd like to join the chorus of praises ... Read More

Finding the key to strengthening the immune response to chronic infections

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as s... Read More

A bad day for science

The virologists who carried out the contentious experiments on influenza H5N1 transmission in ferrets have agreed to remove certain details from their manuscript, according to ScienceInsider. This is a bad day for virology, and for science in general. The decision by the NSABB sets a precedent f... Read More

Frank Fenner, MD, 1914-2010

Australian virologist Frank Fenner, MD was born in Ballarat, Victoria in 1914. He earned a Doctor of Medicine in 1942 at the University of Adelaide, and from 1940 – 1946 he worked on the malaria parasite in Egypt and Papua New Guinea as an officer in the Australian Army Medical Corps. He subsequ... Read More

The Rise of Genomic Superspreaders

One hundred million years ago the earth’s climate was much warmer than today and vast inland seas stretched across entire continents. The land was dominated by charismatic megafauna that would one day serve as inspiration for Sir Arthur Conan Doyle’s novel The Lost World. This period is commonly... Read More

XMRV and CFS – It’s not the end

Yesterday the Chicago Tribune published my reaction to the four papers on the retrovirus XMRV published this week in the journal Retrovirology. I was quoted as saying ”These four papers are probably the beginning of the end of XMRV and CFS”. I wish to retract this statement and explain my reason... Read More

The National Foundation for Infectious Diseases (NFID) announces the availability of two new resources designed to support pneumococcal disease prevention efforts

The National Foundation for Infectious Diseases (NFID)has announced the availability of two new resources designed to support pneumococcal disease prevention efforts on NFID’s website, Adultvaccination.org:

• a professional practice toolkit for healthcare professionals (HCPs)

Th... Read More

Alzheimer''s disease plaques and tangles: Repositories of a herpes simplex/immune system battle leading to neuronal destruction

The protein components of the plaques and tangles seen in the Alzheimer's disease brain offer a clue to the origins of the disease: It turns out that they are heavily enriched in human proteins used by herpes simplex during its life cycle: Many immune system related proteins are also found in th... Read More

The Attendee's Guide to Scientific Meetings

Julian Davies, Professor emeritus at the University of British Columbia and a Fellow of the Royal Society, has authored a humorous post on the Small Things Considered blog on the various methods an attendee of a scientific meeting can employ to enhance "maximum satisfaction and poise" one gets o... Read More

Trust science, not scientists

Whether or not the retrovirus XMRV is a human pathogen has been debated since the virus was first described in 2006. The answer is now clear: the results of Blood XMRV Scientific Research Group, along with a partial retraction of the 2009 Science paper describing identification of the retrovirus... Read More

CDC: Key Facts About Swine Influenza

Good basic info on Swine Flu in humans and pigs. Read More

El podcast del Microbio Nº 200. Baruch Blumberg



























El podcast del Microbio Nº200 is dedicated to the memory of Baruch Blumberg (1925-2011). El podcast del Microbio Nº200 está... Read More

Fun with Fomites - Experiment

coin Read More

TWiP 20 - The whipworm Trichuris trichiura

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.


Vincent and Dickson continue their discussion of nematodes with the whipworm Trichuris trichiura.


Download  Read More

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