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Getting Started with MicrobeWorld

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Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More

TWiP 58 letters

Trudy writes:


Dear Vincent and Dickson,


Listening to TWiP on cyclosporiasis. Because I am all too aware of the possible contamination of many crops as a former public health nurse who worked in epidemiology for my state (Florida), I always wash my fruits and v... Read More

TWiM #142: A membrane-thickness caliper

Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.


Hosts:  Read More

Toxoplasmosis: A T.Gondii Host-pathogen interactome

This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

TWiV 415: Ebola pipettors and the philosopher's clone

Jeremy, Aaron, and Ted join the TWiV team to discuss their work on identifying a single amino acid change in the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells.


Hosts:  Read More

BacterioFiles 269 - Magnetic Microbes Maim MRSA

This episode: Killing pathogens by attaching magnetotactic bacteria to them and then raising the heat with magnetic fields!


(10.6 MB, 11.6 minutes)


Show notes: 


Journal Paper:
Chen C, Chen L, Yi Y, Chen C, Wu L-F, Song ... Read More

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

Abstract - Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other ecological niches, influenced by autogenic and allogenic factors. However, our understanding of microbial colonization in younger versus older CF airways and the association with pulmonary function ... Read More

TWiV 95 Letters

Jim writes:

Some listeners might benefit from reading "The Treatment; why is it so difficult to develop drugs for cancer" in the May 17, 2010 issue of The New Yorker, a nine page article (pp 68-77).


This link goes to the digital edition ( http://archives.newyorker.co... Read More

TWiV 414: Zika in the guys with Diamond

Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication.


Hosts:  Read More

TWiP 78 letters


Meliani writes:


Dear Sir,


My research is focused on the biofilms formation, Motility (swarming and swiming ) and QS in fluorescent Pseudomonas (P. aeruginosa and P. fluorescens).


In laboratory a interaction had been with insect and bacteria metabo... Read More

TWiV 405: All the world's a phage

The TWiXers discuss a study on vertical transmission of Zika virus by Aedes mosquitoes, and uncovering Earth's virome by mining existing metagenomic sequence data.


Hosts: Vincent Rac... Read More

A retrovirus makes chicken eggshells blue

When you purchase chicken eggs at the market, they usually have white or brown shells. But some breeds of chicken produce blue or green eggs. The blue color is caused by insertion of a retrovirus into the chicken genome, which activates a gene involved in the production of blue eggs. Read More

TWiV 270: Homeland virology

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Hosts: Vincent Racaniello and Rich Condit Read More

TWiV 195 Letters

[we began be re-reading part of Deena's email from TWiV 193]


Ben writes:


Hello TWIV Crew,


I must first ap... Read More

MMP #16: Insights into Toxoplasma gondii parasites

Host: Jeff Fox with special guest, Emma Wilson.


Emma H. Wilson of the University of California, Riverside, talks with Jeff Fox about efforts, with her collaborators to determine more precisely how Toxoplasma gondii parasites disrupt the mammalian brain—in this case, the brains of mice... Read More

A Guide to Malaria

In observation of World Malaria Day this April 25, 2009 Scientific American has published a great online resource for people interested in malaria. "The international community has just two years to meet the United Nations's 2010 goal of providing protection and treatment to every person threate... Read More

Common Sense Advice for People Concerned About H1N1 (Swine Flu)

The New York Times has published a nice FAQ ,if you will, about H1N1 and what the general public should keep in mind in terms of worry, protection and symptoms. The article also talks about what public health response is feasible and should be expected. Read More

From a food blender to real-time fluorescent imaging

Although Avery, MacLeod, and McCarty showed in 1944 that nucleic acid was both necessary and sufficient for the transfer of bacterial genetic traits, protein was still suspected to be a critical component of viral heredity. Alfred Hershey and Martha Chase showed that this hypothesis was incorrec... Read More

The Great Epidemic - American Chestnut Blight

Merry Youle of Small Things Considered has a new post about the history of American chestnut blight and the scientific efforts to restock North America with these stately giants through the introduction of biological control agents or with more traditional plant breeding techniques.

Click so... Read More
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