The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.
German researchers suspect that a recent increase in human Cowpox infections in Germany may be spread through the handling of food rats (rodents used for feeding pets or zoo animals) and a decrease in small pox vaccinations among the general public in a PLoS One paper entitled "Cowpox Virus Outb... Read More
Vinny and the capsids answer listener questions about the definition of life, state vaccination laws, the basic science funding problem, viral ecology, inactivation of viruses by pressure, and much more.
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El podcast del Microbio Nº182 resumes the paper by Chenoll et al. published in Applied and Enviroenmental Microbiology that... Read More
Our survey: PowerPoint Show Format
If you have Microsoft’s PowerPoint, you can download our 17-image slide show.
Note: controls will appear in the lower left corner of your monitor. You may also use your arrow keys to move forward and back... Read More
This poster, presented at the 109th ASM general meeting demonstrates the relationship between clinical measures of cystic fibrosis, a common and serious genetic disease, with the microbial ecology of bacteria that colonise the airways of these patients. The technique used to characterise the mi... Read More
Merry Youle of Small Things Considered looks at several bacteria that have borrowed "tail-like particles" from phages and fashioned from it a targeted bacterial killer for their own use.
"These efficient killers are indeed related to phage. One gene cluster in the P. aeruginosa PA... Read More
The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.
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Although many archaea have tough outer cell walls, these walls contain different kinds of amino acids and sugars than those found in bacteria. Archaeal cell membranes also are chemically distinct from bacterial membranes with differing lipid structures and chemical links. This means that drug... Read More
Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.
If you teach students about viruses and bacteria, recent episodes of The Walking Dead have been using the term "antibiotic" to stand for antivirals. Since students are probably watching the show, it might be a good time to highlight the mistake. I summarized the issues at the associated URL (ht... Read More
Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.
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December 2-5 is National Influenza Vaccination Week in the US. This year the push to immunize against flu comes as the disease has begun to increase substantially throughout the United States. A substantial rise in the number of influenza cases typically does not occur until the end of December... Read More
I came across this paper and thought it sounded interesting for a discussion on TWiP:
Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Matt Daugherty writes:
I just listened to the latest TWiM. Thanks for covering our horizontal gene transfer paper! It was great to hear you all talk about it and give your thoughts.
With regards to the selective pressure for retention of the Dae’s in genomes o... Read More
There have been over 60 human infections with avian influenza virus H7N9 in China, and cases have been detected outside of Shanghai, including Beijing, Zhejiang, Henan, and Anhui Provinces. Information on the first three cases has now been published, allowing a more detailed consideration of the... Read More
Dear Vincent, Dickson and Daniel,
I like your idea of a TWIP coffee mug prize (or maybe a mug discount).
In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More
PLoS One has published an interesting paper that considers using smart phones for scientific field data collection and suggests mobile apps could also be beneficial for recruiting ‘citizen scientists’ to contribute data easily to central databases through their mobile phone.
Here's the abstr... Read More
Jeff Fox of Microbe magazine talks with Nancy Connell of the University of Medicine and Dentistry of New Jersey (UMDNJ) on the recent National Research Council report on the FBI’s scientific investigation of the 2001 anthrax attacks Read More
Since vaccines have been so successful at controlling diseases like smallpox and polio in the United States, we often take our relatively epidemic-free world for granted. But less than a lifetime ago, these diseases and others were still real threats to health. Despite vaccines’ successes, many ... Read More