When I was a graduate student at the Medical College of Virginia, many of the microbiologists in my department were very active in the local ASM. Our local ASM provided opportunities to graduate students and postdocs to present their work to an outside audience of scientists from the surroundin... Read More
The World Health Organization’s campaign to eradicate poliomyelitis made impressive inroads in 2012: only 212 cases were reported, compared with 620 the previous year; moreover, India remained polio-free. The dark side of this story is that as wild polio is eliminated, vaccine-associated poliomy... Read More
This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!
(7 MB, 7.5 minutes)
When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More
Got your attention, eh? This page discusses why so many people believe that antibiotics kill viruses, and what you can do about that myth. Actually, it's not even a myth ... antibiotics DO work against viruses. The problem is that the word "antibiotics" is redefined by some to be a synonym of... Read More
"El podcast del microbio" Nº 250 summarize the article published in November by New Scientist about the controversial work on mu... Read More
Poliovirus has made the cover of Time magazine. The Time cover image for the 14 January 2013 issue is a model of poliovirus bound to a soluble form of its cellular receptor, CD155. I was part of the team that solved the structure of this complex in 2000, together with the laboratories of Jim Hog... Read More
There are many elements that go into making a great lecture, but the most important one is to lose the notes. If you are giving lectures in a course at any level, the worst practice you can engage in is to rely on notes. This behavior is problematic for several reasons. You will not properly kno... Read More
Poliovirus recently made the cover of Time magazine. Prompted by a reader question, I searched the Time archive to find out if there have been other virology-themed covers. I found fifteen in all, depicting poliovirus (3), herpesvirus (1), HIV/AIDS (4), influenza (5), and SARS coronavirus (2) (I... Read More
Moselio Schaechter of the Small Things Considered blog reviews the results of a recent paper "Microbial metalloproteomes are largely uncharacterized" from the Department of Biochemistry and Molecular Biology at the University of Georgia, Athens, and ponders its implications.
"Now... Read More
Archaea comes from the Greek word meaning “ancient.” An appropriate name, because many archaea thrive in conditions mimicking those found more than 3.5 billion years ago. Back then, the earth was still covered by oceans that regularly reached the boiling point ... Read More
A one-page primer on the H1N1 flu and what you can do to protect yourself and your family. Read More
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Modern archeologists, excavating ancient Egyptian tombs, have often found something unexpected amongst the tombs’ artifacts: pots of honey, thousands of years old, and yet still preserved. Through millennia, the archeologists discover, the food remains unspoiled, an unmistakable testament to the... Read More
One of the very first things you need to do when getting set up for quantitative PCR (qPCR) is to determine the efficiency of the assay because knowing the assay efficiency is critical to accurate data interpretation. And you have to do this every time you design and purchase a new primer pair.
... Read More
Save the date for Keystone Symposia's meeting on "Fungal Pathogens: From Basic Biology to Drug Discovery" to be held January 15-20, 2012 at the Santa Fe Community Convention Center in Santa Fe, New Mexico. Organized by Joseph Heitman of Duke University, John Taylor of UC Berkeley and Leah E. Cow... Read More
Harvard University is home to some of the world’s finest virologists. But apparently they do not communicate with the writers at Harvard Magazine, where a botched story on the avian H5N1 influenza virus has just been published. Read More
Evolution proceeds by selection of mutants that arise by error-prone duplication of nucleic acid genomes. It is believed that mutations that are selected in a gene are dependent on those that have preceded them, an effect known as epistasis. Analysis of a sequence of changes in the influenza vir... Read More
There are many reasons why bacteria evolve resistance to antibacterials, but one of the preventable reasons is the over-prescription of antibacterials to patients who don't have bacterial infections. But how to get people to stop asking for antibacterials? My suggestion is to stop using the wor... Read More
El Podcast del Microbio" Nº 149 is based in the Nature Physics article by W Roos y G.J.L Wuite. El Podcast del Microbio Nº ... Read More
About 2% of the world’s population is chronically infected with hepatitis C virus (HCV). This enveloped, positive-strand RNA virus was discovered in 1989, but serological and phylogenetic evidence indicates that it has been infecting humans for hundreds of years, perhaps as long ago as the 14th ... Read More