Bacteria can elaborate complex patterns of development that are dictated by temporally ordered patterns of gene expression, typically under the control of a master regulatory pathway. For some processes, such as biofilm development, regulators that initiate the process have been identified but s... Read More
When antibiotics first started being used in the 1940's they were considered a "miracle drug". It seemed that bacterial infections would no longer be a problem for the world. However, recently, one gene is making it seem as though the end of antibiotics is at hand. This gene is New Delhi metallo... Read More
Are there environments where there are abundant bacteria and no phages? Sounds like one of our Talmudic Questions, but this one has a specific answer, and that answer is Yes. That environment was found within a cystic fibrosis (CF) lung.
This story comes from a pair of papers recently publish... Read More
Now that we have experienced several months of the H1N1 pandemic, what have we learned about how it was handled? Watch Dr. Nicole Lurie (U.S. Department of Health and Human Services) and Dr. Kathryn Edwards (Vanderbilt University), discuss the public health responses to H1N1. Participants compar... Read More
Most of you are probably back to work after the ASM conference in San Diego. It was a great conference with a lot of exciting talks and posters and we hope you enjoyed our beautiful city.
MO BIO Labs presented four posters at ASM and the PDFs are now available online for viewing. These were t... Read More
Dean Dawson, Associate Member of the Cell Cycle and Cancer Biology Research Program at the Oklahoma Medical Research Foundation, has authored a post on Small Things Considered which explores Candida's chromosomal instability and unorthodox reproduction process.
"Who hasn't heard of Candida? I... Read More
El podcast del microbio Nº 361 summarize the article writen by Marks LR, Reddinger RM and Hakansson AP and published in mBio about the high levels of genetic recombination in Streptococcus pneumoniae ... Read More
Dear Vince and Alan,
Being a seasoned virologist and a science writer, I was hoping you could discuss the interface between basic science, public health, the media and the general public...
While I was listening to you d... Read More
In this blog post, I describe a simple "colony transformation" experiment I have done with my freshman students, illustrating transformation, antibiotic resistance, and GFP. The visual aspects help drive home the points effectivel. Read More
Eric asked for “advice on how to bridge the gap between clinical medicine, public health, and virology research.” I asked Scott Hammer MD for his thoughts on this question. Here is Dr. Hammer’s response:
Thanks for forwarding this comment. In response, I’d inform y... Read More
Hello TWiM team,
El podcast del Microbio Nº258 deals with the sequencing of the Yersinia pestis strain that causes the Black Death. El podcast de... Read More
El podcast del Microbio Nº255 explains the use of the fungus Beauveria bassiana as bioinsecticide for the control of the red pa... Read More
Theoretical physicist and futurist Michio Kaku looks at the revolution in genetics and biotechnology, which promises unprecedented health and longevity but also raises fears of a future where we can genetically engineer people. The documwentary asks will we, as transhumanists expect, evolve into... Read More
It’s not hard to see that men are more likely to engage in risky behaviors than women, or that crime rates are many times higher among men, but this tendency to break the rules also extends to male scientists, according to a study to be published on January 22 in mBio®, the online open-access jo... Read More
Earlier this month the European Molecular Biology Laboratory (EMBL) published the DNA sequence of the genome of HeLa cells, the cell line that is widely used for research in virology, cell biology, and many other areas. This cell line was produced from a tumor taken from Henrietta Lacks in 1951.... Read More
The XMRV retrovirus has been implicated in chronic fatigue syndrome and prostate cancer. A homology search comparing retroviral with human proteins revealed short contiguous amino acid strings (typically 5-8 aa) matching human proteins whose dysfunction might be expected to cause fatigue, includ... Read More
El Podcast del Microbio" Nº 152 and 153 deals with the history of the infamous Tuskegee Syphilis Experiment and its follow-... Read More
Deans of public health schools in the United States have sent a letter to President Obama, in which they criticize the use of a vaccination campaign by the Central Intelligence Agency in Pakistan to hunt for Osama bin Laden. I wonder if he will reply. Read More
This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!
(7 MB, 7.5 minutes)
When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More