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TWiP 83 letters


Robin writes:


Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).


Thick blood smears is de rigueur.
So... Read More

TWiV 288: ebircsnart esreveR

The Twivsters discuss how reverse transcriptase encoded in the human genome might produce DNA copies of RNA viruses in infected cells.


Hosts: Vincent Racaniello Read More

TWiV 319: Breaking breakbone

The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.


Hosts: Vincent Racaniello Read More

World Polio Day

Today, 24 October 2012, is World Polio Day:

World Polio Day (October 24) was established by Rotary International over a decade ago to commemorate the birth of Jonas Salk, who led the first team to develop a vaccine against poliomyelitis. Use of this inactivated poliovirus vaccine and subseque... Read More

Everyone Rowing in the Same Direction

Is there such a thing as an obligatorily multicellular prokaryote? Merry Youle of the Small Things Considered blog reviews a recent paper published in the May issue of Applied and Environmental Microbiology that announces the finding of a new subgroup within magnetotactic multicellular prokaryot... Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

A new virology course at Columbia University

Tomorrow is the start of my new virology course at Columbia University. The course, Biology W3310, is aimed at advanced undergraduates and will be taught at the Morningside Campus of Columbia University. Read More

60 of the World's most memorable research papers

The Royal Society, founded in London in 1660 and one of the world's oldest scientific institutions, is marking the start of its 350th year by putting 60 of its most memorable research papers online. Several of these documents include papers by Sir Isaac Newton, Benjamin Franklin, and even Antoni... Read More

NSF Launches Science360 Radio for Web, iPhone and Android

The National Science Foundation has just launched Science360 Radio, a website and app for smart phones and iDevices, that streams science-focused audio content. (Disclaimer: All of MicrobeWorld's podcasts are included.) There are over 100 shows featured and the app is free.

While this much co... Read More

Seth Berkley: HIV and flu - the vaccine strategy

Seth Berkley explains how smart advances in vaccine design, production and distribution are bringing us closer than ever to eliminating a host of global threats -- from AIDS to malaria to flu pandemics. Read More

Milestones in Microbiology at Cold Spring Harbor Laboratory

Last week I was at Cold Spring Harbor Laboratory to attend a ceremony designating the well-known laboratory on Long Island as a Milestone in Microbiology site. The purpose of this program, which is administered by the American Society for Microbiology, is to recognize institutions that have subs... Read More

TWiP 82 letters


Allan writes:


Dear Vincent, Dickson and Daniel,


I like your idea of a TWIP coffee mug prize (or maybe a mug discount).


In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

Inhibition of XMRV by a weapon of mass deamination

All mammalian genomes contain genes encoding Apobec proteins. Several members of this protein family (the name stands for apolipoprotein B mRNA editing complex) are induced by interferon and are intrinsic antiretroviral proteins. Apobec proteins inhibit the replication of XMRV, a new human retro... Read More

TWiM #6 transcript

Here is a transcript of TWiM episode #6, "Antibacterial therapy with bacteriophage: Fact or fiction?". Thanks to Steve Stokowski for transcription.


The transcript is also available as a pdf file - click here to download Read More

TWiV 311: Bulldogs go viral

Vincent visits the University of Georgia where he speaks with Zhen Fu and Biao He about their work on rabies virus and paramyxoviruses.


 


Host: Vincent Racaniello. Guests:  Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.


Host:  Read More

My first "Mu-Tube" video promoting microbial literacy: What does "microbiology" mean to students?

For my Microbiology course at the University of Puget Sound, I decided to ask my new crop of "micronauts" what the word "microbiology" meant to them on the first day of class. Here are their answers. My wife Jennifer Quinn and I put this together using art from former students. Hopefully, thi... Read More

E.O. Wilson: Help build the Encyclopedia of Life

As noted entomologist E.O. Wilson accepts his 2007 TED Prize, he makes a plea on behalf of his constituents, the insects and small creatures, to learn more about our biosphere. Wilson states that as we're still discovering tiny organisms indispensable to life we're steadily, methodically, and vi... Read More

Universal influenza vaccines

The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn... Read More

Cell Organization and Cell Motility (Part 1) by Julie Theriot

This lecture covers the biochemical basis of actin-based motility (focusing on the pathogen Listeria as a model system for this process), the biophysical mechanism of polymerization-based force generation, and an evolutionary perspective of cell shape in prokaryotes and eukaryotes. The first par... Read More
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