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Evidence-based antibiotic usage

New recommendation encourages physicians to prescribe _antibacterials_ instead of antibiotics for bacterial infections. This recommendation is based on compelling evidence that the word "antibiotic" confuses almost everyone, including some doctors. The confusion leads to strong patient demands... Read More

Archaea of Note


  • Lobus fulgidus is a sulfur-reducer that can sour oil wells.

  • Halobacteria are salt-loving microbes that give a pink tinge to salt water evaporation ponds, the Dead Sea and salted fish.

  • Pyrolobus fumarii led scientists to extend the upper te... Read More

A system‐level model for the microbial regulatory genome

Microbes can tailor transcriptional responses to diverse environmental challenges despite having streamlined genomes and a limited number of regulators. We present data‐driven models that capture the dynamic interplay of the environment and genome‐encoded regulatory programs of two types of prok... Read More

Taq Polymerase and the PCR

Morehouse College Biology students Rob Williams and Tony Gibson present on the process of Taq production and the polymerase chain reaction. Read More

TWiM #49 transcript

Here is a transcript of TWiM episode #49, "Grape-like clusters". Thanks to Frank Shinneman for transcription.


The transcript is also available as a pdf file - click... Read More

The U.S. Army’s updated biomedical regulations for select agents

A new post on the Bulletin for Atomic Scientists website reviews the U.S. Army's revised regulations for its biomedical labs. The updated requirements intends to clarify vague language in civilian biological agents guidelines. In addition, "the new regulations establish stricter controls on t... Read More

TWiV 295: A nonslip grippe and Lassa's LAMP

The TWiVome discusses an miRNA based strategy to mitigate risk of gain of function studies, and identification of a second receptor required for Lassa virus entry.


Hosts: Vincent Racaniello,&n... Read More

A single amino acid change switches avian influenza H5N1 and H7N9 viruses to human receptors

Two back-to-back papers were published last week that provide a detailed analysis of what it would take for avian influenza H5N1 and H7N9 viruses to switch to human receptors. A single amino acid change in the viral hemagglutinin protein is sufficient to quantitatively change binding of the viru... Read More

Mad Dogs and Microbiologists

Guest blogger William C. Summers, Yale University School of Medicine, authors a post at Small Things Considered about the potential for a new rabies vaccine as evidenced in a recent PLoS paper titled "Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombina... Read More

El podcast del Microbio Nº 286. Mutaciones tempranas en el VIH (Early mutations in HIV)



























El podcast del Microbio Nº 286 summarize the article by Henn et al published in PLoS: Pathogens about the impact of early minor ... Read More

Physical Virology

A post by Manuel Sánchez, host of the Spanish blog, Curiosidades de al Microbiologia, on an article entitled "Physical Virology " that appeared in Nature Phyisics, discuses the ideas and potential of a new discipline that studies viruses from a physical perspective.

"Viruses are able to spont... Read More

Event - Ethical Issues in Synthetic Biology

June 24, 2009 12:30 – 1:30 PM

The emerging field of synthetic biology will allow researchers to create biological systems that do not occur naturally as well as to re-engineer existing biological systems to perform novel and beneficial tasks. As the science and its applications develop, a com... Read More

An Inactive Mine Provides Active Opportunities

Elio Schaechter of Small Things Considered describes the work by members of Jill Banfield’s lab at Berkeley on a unique set of mine-dwelling microorganisms dubbed ARMAN (for Archaeal Richmond Mine Acidophilic Nanoorganisms). These microbes illustrate many surprising characteristics such as "thei... Read More

Biology of Bacteria

Here's a nice edu resource-related video about the biology of bacteria that the team over at SciVee.tv posted. It looks like it originally came from Maryland Public Television. This is probably good for many intro to microbiology type courses and high school level life science classes. Read More

TWiP 65 letters

 


Perry writes:


Greetings Vincent and Dick,


Hooray for finally mentioning G. pulchrum in episode 62, my most favorite parasite and one worthy of further discussion. As a diagnostic veterinary pathologist, I encounter this spirurid in approximately... Read More

TWiM #6 transcript

Here is a transcript of TWiM episode #6, "Antibacterial therapy with bacteriophage: Fact or fiction?". Thanks to Steve Stokowski for transcription.


The transcript is also available as a pdf file - click here to download Read More

Curbing Domestic Violence Key to Reducing HIV Infection Among South African Women

Women in South Africa who are victims of domestic violence are more likely to become infected with HIV compared to women who do not experience such behavior, according to a study published June 16, 2010 in The Lancet'‘s Online First.

Nearly one in seven new HIV infections could be prevented i... Read More

Promiscuous Bacteria and Viral Playboys

Bacteria have been sexually promiscuous, swapping genes with gusto, for a very long time. More than 15% of E. coli's genome has arrived via horizontal gene transfer (HGT), with some 200 installments having turned up since it diverged from Salmonella 100 million years ago. And, as you are probabl... Read More

CDC's 2009 H1N1 Vaccination Recommendations (Podcast)

Dr. Tony Fiore discusses who should be vaccinated against 2009 H1N1 flu during the 2009-2010 season. He explains the target groups for vaccination, and how these groups differ from those recommended for seasonal flu vaccination. Read More

BacterioFiles 187 - Bacteria Bolster Bedbug Biotin

This episode: Some Wolbachia bacteria produce vitamin B7 for their insect hosts!


(7.1 MB, 7.75 minutes)


Show notes: 
Journal Paper


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