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TWiV 319: Breaking breakbone

The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.


Hosts: Vincent Racaniello Read More

Toxoplasmosis: A T.Gondii Host-pathogen interactome

This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More

MdlM116: La importancia de los virus como patógenos emergentes en América Latina

Los virus son considerados por la mayoría como patógenos en todo tipo de entidades biológicas.  Sin embargo la gran mayoría de los virus son inocuos a sus células hospedero.  Nuestro invitado de hoy, el Dr. Paolo Zanotto es investigador y profesor en la Universidad de Sao Paolo, Bra... Read More

From a food blender to real-time fluorescent imaging

Although Avery, MacLeod, and McCarty showed in 1944 that nucleic acid was both necessary and sufficient for the transfer of bacterial genetic traits, protein was still suspected to be a critical component of viral heredity. Alfred Hershey and Martha Chase showed that this hypothesis was incorrec... Read More

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

Abstract - Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other ecological niches, influenced by autogenic and allogenic factors. However, our understanding of microbial colonization in younger versus older CF airways and the association with pulmonary function ... Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

TWiV 384: Agent 003, a view to a fish kill

Hosts: Vincent RacanielloDickson DespommierAlan Dove and  Read More

TWiV 244: Back in the CVVR

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Hosts: Vincent Racaniello and Read More

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Do We Need a Climate Solution for Indoors?

We typically spend close to 90 percent of our time inside - at school, work and home. While outdoor air quality is very important, so too is the quality of the air we breathe at home and the office. Yet most of us know very little about the condition of our indoor climate.  The chemicals ... Read More

BacterioFiles 253 - Probiotics Promote Protective Pathway

This episode: In mice and fruit flies, Lactobacillus species induce gut cells to protect themselves from reactive oxygen compounds!


(8.2 MB, 8.9 minutes)


Show notes: 
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TWiP 83 letters


Robin writes:


Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).


Thick blood smears is de rigueur.
So... Read More

TWiV 118: The virus always rings twice

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Hosts: Vincent Racaniello, Read More

TWiV 380: Viruses visible in le microscope photonique

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 282: Tamiflu and tenure too

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Hosts:  Read More

Clostridium difficile in the domicile

Patients undergoing FMT have often suffered for years prior to the therapy. If their homes have been contaminated with the eradicated microbe, could patients suffer a relapse by way of reinoculation? This was the question asked by a group of physician scientists, whose findings were recently pub... Read More

Use of a Class 1 Safety Cabinet (video)

This video shows you how a Class 1 microbiological safety cabinet works. Read More

SBTM12 - Sequence-Based Typing Methods for Microorganisms / Hands-on Bioinformatics Training Course - PORTUGAL

Applications are OPEN!
Deadline Sept 10th Course dates Sept 25th - 28th 2012

A highly intereactive course where participants will learn a lot about sequence-based typing methods. GTPB courses are designed to give maximum transfer of skills and user independence. Course fee = Euro 320. Lo... Read More

The Great Epidemic - American Chestnut Blight

Merry Youle of Small Things Considered has a new post about the history of American chestnut blight and the scientific efforts to restock North America with these stately giants through the introduction of biological control agents or with more traditional plant breeding techniques.

Click so... Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

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