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Getting Started with MicrobeWorld

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TWiV 374: Discordance in B

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Viral bioinformatics: Dotplot

Dotplots are an extremely useful way of visualizing comparisons of small and large DNA sequences (as well as protein sequences), providing insight into the degree of similarity, deletions, insertions and direct and indirect repeats. In a dotplot, each nucleotide, or small window of nucleotides, ... Read More

TWiV 260: Badgers go viral

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Host: Vincent Racaniello


Guests: Read More

The Limitations of the Luria-Bertani Medium

Hiroshi Nakaido, PBD Faculty Scientist, Structural Biology Department, and Professor of Biochemistry and Molecular Biology, UC Berkeley, has authored a guest post on the Small Things Considered Blog regarding the limitations of LB medium.

"LB broth contains, per ml, 10 mg tryptone (... Read More

TWiV 393: Lovers and livers

The TWiVerati revisit possible sexual transmission of Zika virus, and reveal how a cell protein that allows hepatitis C virus replication in cell culture enhances vitamin E mediated protection against lipid peroxidation.


Hosts:  Read More

Wasps do a gain-of-function experiment in caterpillars

Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More

TWiM 100 Letters

Matt Daugherty writes:


I just listened to the latest TWiM. Thanks for covering our horizontal gene transfer paper! It was great to hear you all talk about it and give your thoughts.


With regards to the selective pressure for retention of the Dae’s in genomes o... Read More

TWiV 277: My podcast Vinny

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Hosts: Glenn Rall, Ann Skalka, and  Read More

BacterioFiles Micro Edition 29 - Mid-air Microbial Mix

This episode: A sample of bacteria in city air!


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TWiM 64 Letters

Tim writes:


Vincent and friends,


While driving around a field cutting hay lost in my science podcast playlist the episode of TWIM #61 came up and I had to listen intently as salmonella typhimurium came up as this is a common enteric issue in agriculture. When ... Read More

TWiV 245: Writing Principles of Virology

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Host: Vincent Racaniello


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Clostridium difficile in the domicile

Patients undergoing FMT have often suffered for years prior to the therapy. If their homes have been contaminated with the eradicated microbe, could patients suffer a relapse by way of reinoculation? This was the question asked by a group of physician scientists, whose findings were recently pub... Read More

BacterioFiles Micro Edition 32 - Virus Versus Malignancy Matrix

This episode: Virus + bacterial enzyme = cancer killer!


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Read More

MMP #15: A Scientific Roadmap for Antibiotic Discovery

Host: Jeff Fox with special guests, Carolyn Shore and Ruben Tommasi.


Carolyn Shore of Pew Charitable Trusts in Washington, D.C., and Ruben Tommasi of Entasis Therapeutics in Waltham, Massachusetts, talk with Jeff Fox about what’s needed to identify and develop new antimicrobial agents... Read More

TWiV 216: Processing VIRALGUUAACACCAGRNA

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Hosts: Vincent Racaniello, Alan Dove, Read More

Cyanobacteria: Growing a Green Future Around the Clock

Spencer Diamond and Britt Flaherty, PhD students at UCSD, Spencer in the Susan Golden Laboratory and Britt in the James Golden Laboratory, author a post on Small Things Considered about the green potential for cyanobacteria.

"With such famous bacteria as Escherichia coli and Bacillus subtili... Read More

TWiV 229: Partly cloudy with a high of H7N9

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Hosts: Vincent Racaniello, Rich Condit, Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

TWiV 401: Vector victorious

Zika virus spreads in the USA, a Zika virus DNA vaccine goes into phase I trials, and how mosquito bites enhance virus replication and disease, from the friendly TWiFolk Vincent, Dickson, Alan, and Kathy.


Hosts:  Read More

TWiV 330: A swinging gate

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

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