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CDC's 2009 H1N1 Vaccination Recommendations (Podcast)

Dr. Tony Fiore discusses who should be vaccinated against 2009 H1N1 flu during the 2009-2010 season. He explains the target groups for vaccination, and how these groups differ from those recommended for seasonal flu vaccination. Read More

BacterioFiles 179 - Functionless Phages Feel Fatiguing

 This episode: Defective phages in bacterial genomes can still have burdensome effects! Why do the bacteria keep them around?


(10.4 MB, 11.3 minutes)


Show notes: 
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An Inactive Mine Provides Active Opportunities

Elio Schaechter of Small Things Considered describes the work by members of Jill Banfield’s lab at Berkeley on a unique set of mine-dwelling microorganisms dubbed ARMAN (for Archaeal Richmond Mine Acidophilic Nanoorganisms). These microbes illustrate many surprising characteristics such as "thei... Read More

TWiM #46 transcript

Here is a transcript of TWiM episode #46, "Spore!". Thanks to Frank Shinneman for transcription.


The transcript is also available as a pdf file - click here to download.


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Dr. Francis Su's View on "Grace" in Teaching---A MUST Read!

Dr, Francis Su is a mathematician at Harvey Mudd College in Southern California. Last week, he was honored with the prestigious Haimo Teaching Award of the Mathematics Association of America at the Join Math Meetings in San Diego. His acceptance speech is inspiring to any educator and any stud... Read More

Avian influenza H7N9 viruses isolated from humans: What do the gene sequences mean?

There have been over 60 human infections with avian influenza virus H7N9 in China, and cases have been detected outside of Shanghai, including Beijing, Zhejiang, Henan, and Anhui Provinces. Information on the first three cases has now been published, allowing a more detailed consideration of the... Read More

TWiP 3 letters

Björn writes: (first letter to TWiP)


Hi Dick and Vincent,



My name is Björn. I am a biochemist and PhD student working on trypanosomes here in Germany. I am a long time listener of your twiv podcast and just listened to the first  Read More

A single amino acid change switches avian influenza H5N1 and H7N9 viruses to human receptors

Two back-to-back papers were published last week that provide a detailed analysis of what it would take for avian influenza H5N1 and H7N9 viruses to switch to human receptors. A single amino acid change in the viral hemagglutinin protein is sufficient to quantitatively change binding of the viru... Read More

TWiV 269: Herpesvirus stops a nuclear attack

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Hosts: Vincent Racaniello, Dickson Despommier Read More

Design and Testing of Protein Combinatorial Libraries

In this video Stephen L. Mayo, Bren Professor of Biology and Chemistry, California Institute of Technology, discusses the challenges of designing new proteins that fold into a particular structure or perform a particular function. One method is to computationally design a protein based solely up... Read More

Scientists for Science

Scientists for Science are confident that biomedical research on potentially dangerous pathogens can be performed safely and is essential for a comprehensive understanding of microbial disease pathogenesis, prevention and treatment. The results of such research are often unanticipated and accrue... Read More

El podcast del Microbio Nº 286. Mutaciones tempranas en el VIH (Early mutations in HIV)



























El podcast del Microbio Nº 286 summarize the article by Henn et al published in PLoS: Pathogens about the impact of early minor ... Read More

Curbing Domestic Violence Key to Reducing HIV Infection Among South African Women

Women in South Africa who are victims of domestic violence are more likely to become infected with HIV compared to women who do not experience such behavior, according to a study published June 16, 2010 in The Lancet'‘s Online First.

Nearly one in seven new HIV infections could be prevented i... Read More

TWiV 48

Rodney writes:


Hello, I have been an avid listener of TWiV over the last 9 months or so and have very much enjoyed the podcast. It is always great to hear a broad, informed discussion on virology, and your recent podcast on viral classification was of particular interest to m... Read More

The most important paper ever in microbiology

Jonathan Eisen (@phylogenomics on Twitter) has a new post on his The Tree of Life blog that looks at why the paper "Phylogenetic structure of the prokaryotic domain: The primary kingdoms" by Carl Woese and George Fox may be the most important paper (see http://www.pnas.org/content/74/11/5088.ful... Read More

El podcast del Microbio 110 y 111: La estirpe de Caín

The Nº 110 and 111 of "El podcast del microbio" describes the fratricide behaviour of Streptococcus pneumoniae and the role of Lyt C autolysisn. En "El podcast del microbio" Nº 110 y 111 se habla del comportamiento fratricida de Streptococcus pneumoniae y el papel de la autolisina Lyt C.

{mp... Read More

Do Hand Sanitizer and Liquid Hand Soap Remove Viruses?

While reading my back issues of Applied and Environmental Microbiology (AEM), I came across an interesting paper that detailed an in-depth study on the effectiveness of hand cleaners to remove Norwalk virus (NV) from intentionally contaminated hands.

Yes that’s right – intentionally contamina... Read More

Audio interview with Dylan Pillai of the University of Toronto

Jeff Fox of Microbe magazine interviews Dylan Pillai of the University of Toronto on how genomic analysis is used by epidemiologists and clinical microbiologists to reconstruct bacterial disease outbreaks or analyze difficult individual cases Read More

Should variola virus, the agent of smallpox, be destroyed?

Later this month (May 2014) the World Health Assembly will decide whether to destroy the remaining stocks of variola virus – the agent of smallpox – or to allow continued research on the virus at WHO-approved laboratories. We are interested in your opinion on this issue. Please follow the link t... Read More

TWiV 297: Ebola! Don't panic

The TWiVites present an all-ebolavirus episode, tackling virology, epidemiology, and approaches to prevention and cure that are in the pipeline.


Hosts: Vincent Racaniello Read More

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