In regard to your question as to cases of known alteration of host behavior by virus that increases the rate of contact among hosts (Twiv 70), the most dramatic example is given by rabies. This extraordinary virus can convert a neurologically and behaviorally... Read More
The TWiPanosomes solve the case about the Young Woman who Went to Belize, and relate how sandfly saliva skews the immune response and increases risk of cutaneous leishmaniasis.
Hosts: Read More
This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More
Both Nature and the New York Times have weighed in on the resumption of influenza H5N1 research. In an editorial from 23 January 2013, Nature opines that “Experiments that make deadly pathogens more dangerous demand the utmost scrutiny”. They call for a quantitative risk-benefit analysis of H5N1... Read More
The Global Water Challenge (GWC) is a coalition of leading organizations in the water and sanitation sector. In this video GWC finalist David Kuria of Ecotact Limited, a Kenyan company dedicated to bringing public toilets to an area where there were only two for 60,000 people, discusses the need... Read More
Thirty years ago this month I arrived in the Department of Microbiology at Columbia University’s College of Physicians and Surgeons (P&S) to start my own laboratory. Thirty is not only a multiple of ten (which we tend to celebrate), but also a long time to be at one place. It’s clearly time to r... Read More
Architecture student Magnus Larsson details his bold plan to transform the harsh Sahara desert using bacteria and a surprising construction material: the sand itself. Read More
Merry Youle of Small Things Considered has a new post about the history of American chestnut blight and the scientific efforts to restock North America with these stately giants through the introduction of biological control agents or with more traditional plant breeding techniques.
Click so... Read More
This episode: Bacterial ghosts could make good vaccines for different things!
(9.8 MB, 10.7 minutes)
Hi Vince and Dick!
Has anyone volunteered to do transcripts for TWIP? I love this show, and I'd love to be able to contribute in some way. Forgive me if transcripts already exist and I'm just not finding them on the website. If no one is already... Read More
Chimpanzees from African sanctuaries carry drug-resistant, human-associated strains of the bacteria Staphlyococcus aureus, a pathogen that the infected chimpanzees could spread to endangered wild ape populations if they were reintroduced to their natural habitat, a new study shows.
The study ... Read More
Viruses exist for one purpose only: to reproduce. To do that, they have to take over the reproductive machinery of suitable host cells.
Upon landing on an appropriate host cell, a virus gets its genetic material inside the cell either by tricking the host cell to pull it inside, like ... Read More
Here's an interesting essay published in PLoS Biology by Michael Emerman and Harmit S. Malik on paleovirology, a topic recently discussed by Welkin Johnson, on the Small Things Considered blog.
<... Read More
This episode: Flu vaccine made by bacteria!
A new paper in PLoS recommends two vaccination strategies to better prevent whooping cough.
"In the absence of adolescent or adult vaccination, pertussis incidence among adults is predicted to more than double in 20 years. Implementing an adult program in addition to childhood and adolescent... Read More
For thousands of years, epidemics of contagious diseases were believed to be caused by the wrath of the gods, configuration of stars, or miasma. The association of specific microorganisms with disease came about as a consequence of the work of the German physician Robert Koch. He formulated a se... Read More